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Original Articles
Factors Associated With Long-term Retention in Antiretroviral Therapy Among People Living With HIV: Evidence From a Tertiary Hospital in Jakarta, Indonesia
Ifael Yerosias Mauleti, Krishna Adi Wibisana, Djati Prasetio Syamsuridzal, Sri Mulyati, Vivi Lisdawati, Ika Saptarini, Nurhayati , Armedy Ronny Hasugian, Harimat Hendarwan
J Prev Med Public Health. 2024;57(3):252-259.   Published online April 30, 2024
DOI: https://doi.org/10.3961/jpmph.23.512
  • 1,007 View
  • 144 Download
AbstractAbstract AbstractSummary PDFSupplementary Material
Objectives
This study investigated factors associated with the retention of people living with human immunodeficiency virus (HIV) on antiretroviral therapy (ART) during the first 3 years of treatment.
Methods
A retrospective study using electronic health records was conducted at a tertiary hospital in Jakarta, Indonesia. Adult HIV-positive patients who started ART from 2010 until 2020 were included. A binary logistic regression model was used to identify factors associated with ART retention in the first 3 years.
Results
In total, 535 respondents were included in the analysis. The ART retention rates for the first, second, and third years were 83.7%, 79.1%, and 77.2%, respectively. The multivariate analysis revealed a negative association between CD4 count when starting ART and retention. Patients with CD4 counts >200 cells/mL were 0.65 times less likely to have good retention than those with CD4 counts ≤200 cells/mL. The year of starting ART was also significantly associated with retention. Patients who started ART in 2010-2013 or 2014-2016 were less likely to have good retention than those who started ART in 2017-2020, with adjusted odds ratios of 0.52 and 0.40, respectively. Patients who received efavirenz-based therapy were 1.69 times more likely to have good retention than those who received nevirapine (95% confidence interval, 1.05 to 2.72).
Conclusions
Our study revealed a decline in ART retention in the third year. The CD4 count, year of enrollment, and an efavirenz-based regimen were significantly associated with retention. Patient engagement has long been a priority in HIV programs, with interventions being implemented to address this issue.
Summary
Key Message
The administration of antiretroviral therapy to HIV patients has resulted in increased rates of survival, enhanced quality of life, and less transmission of the virus. Nevertheless, a negative correlation exists between the length of antiretroviral therapy and patient retention in care. Our study used data from a tertiary hospital and indicated a decrease in the retention rate of antiretroviral therapy over the third year. Retention was associated with the CD4 count, year of enrollment, and the use of an efavirenz-based treatment. Emphasizing patient engagement has been a longstanding focus in HIV programs, with initiatives being implemented to tackle this matter.
A Peer-support Mini-counseling Model to Improve Treatment in HIV-positive Pregnant Women in Kupang City, East Nusa Tenggara, Indonesia
Artha Camellia, Plamularsih Swandari, Gusni Rahma, Tuti Parwati Merati, I Made Bakta, Dyah Pradnyaparamita Duarsa
J Prev Med Public Health. 2023;56(3):238-247.   Published online April 11, 2023
DOI: https://doi.org/10.3961/jpmph.22.516
  • 2,069 View
  • 129 Download
  • 2 Web of Science
  • 2 Crossref
AbstractAbstract PDF
Objectives
Low adherence to antiretroviral (ARV) therapy in pregnant women with human immunodeficiency virus (HIV) increases the risk of virus transmission from mother to newborn. Increasing mothers’ knowledge and motivation to access treatment has been identified as a critical factor in prevention. Therefore, this research aimed to explore barriers and enablers in accessing HIV care and treatment services.
Methods
This research was the first phase of a mixed-method analysis conducted in Kupang, a remote city in East Nusa Tenggara Province, Indonesia. Samples were taken by purposive sampling of 17 people interviewed, consisting of 6 mothers with HIV, 5 peer facilitators, and 6 health workers. Data were collected through semi-structured interviews, focus group discussions, observations, and document review. Inductive thematic analysis was also performed. The existing data were grouped into several themes, then relationships and linkages were drawn from each group of informants.
Results
Barriers to accessing care and treatment were lack of knowledge about the benefits of ARV; stigma from within and the surrounding environment; difficulty in accessing services due to distance, time, and cost; completeness of administration; drugs’ side effects; and the quality of health workers and HIV services.
Conclusions
There was a need for a structured and integrated model of peer support to improve ARV uptake and treatment in pregnant women with HIV. This research identified needs including mini-counseling sessions designed to address psychosocial barriers as an integrated approach to support antenatal care that can effectively assist HIV-positive pregnant women in improving treatment adherence.
Summary

Citations

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  • Letter to the Editor: Supporting the Sick and the Vulnerable
    Fides A. del Castillo
    Journal of Preventive Medicine and Public Health.2023; 56(4): 392.     CrossRef
  • Author Response: Supporting the Sick and the Vulnerable
    Artha Camellia, Gusni Rahma
    Journal of Preventive Medicine and Public Health.2023; 56(4): 394.     CrossRef
Special Article
Introduction to Mediation Analysis and Examples of Its Application to Real-world Data
Sun Jae Jung
J Prev Med Public Health. 2021;54(3):166-172.   Published online May 7, 2021
DOI: https://doi.org/10.3961/jpmph.21.069
  • 9,013 View
  • 427 Download
  • 15 Web of Science
  • 19 Crossref
AbstractAbstract AbstractSummary PDF
Traditional epidemiological assessments, which mainly focused on evaluating the statistical association between two major components-the exposure and outcome-have recently evolved to ascertain the in-between process, which can explain the underlying causal pathway. Mediation analysis has emerged as a compelling method to disentangle the complex nature of these pathways. The statistical method of mediation analysis has evolved from simple regression analysis to causal mediation analysis, and each amendment refined the underlying mathematical theory and required assumptions. This short guide will introduce the basic statistical framework and assumptions of both traditional and modern mediation analyses, providing examples conducted with real-world data.
Summary
Korean summary
본 리뷰에서는 전통적으로 쓰여왔던 회귀분석 기반 매개요인분석방법과 인과적 매개요인분석방법에 대하여 간략히 소개하며, 또한 예시를 들어 설명하고 있다. 매개요인 분석 전에는 필요한 가정들이 맞는 지를 확인하는 것이 중요하다. 또한 분석결과를 올바르게 해석하는 것 또한 요구된다. 이러한 방법은 그동안의 노출-결과만을 다루는 단순 역학연구을 뛰어넘어, 인구집단연구에서 매커니즘을 밝히는 도구로서 유용하게 쓰일 것이다.

Citations

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    Journal of Cachexia, Sarcopenia and Muscle.2024; 15(1): 138.     CrossRef
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Perspective
iDENTIfyme Informative Campaign: Raising Forensic Dental Identification Awareness in the Community
Emilio Nuzzolese
J Prev Med Public Health. 2021;54(3):218-219.   Published online April 20, 2021
DOI: https://doi.org/10.3961/jpmph.21.081
  • 3,315 View
  • 115 Download
  • 1 Crossref
AbstractAbstract PDF
The identification of human remains can be performed visually through families and next-of-kin, but it is not advisable to rely only on visual recognition; instead, it is preferable to conduct a forensic comparison of antemortem and postmortem data for primary identifiers (fingerprints, DNA, and dental data). A dental autopsy is particularly valuable in the identification process of skeletonized, carbonized, saponified, and fragmented human remains. The principal challenge in the identification process is the search and collection of antemortem data. To this end, all dental information held on a missing person can represent a precious source of individualizing information that families should share with the police or investigating agencies after reporting a disappearance.
Summary

Citations

Citations to this article as recorded by  
  • Creating Awareness Regarding Forensic Odontology Among Non-Forensic Persons for Successful Dental Identifications
    H. Pandey, E. Nuzzolese
    Journal of Forensic Dental Sciences.2022; : 136.     CrossRef
Original Articles
The Relationship Between Obesity, Overweight, and the Human Development Index in World Health Organization Eastern Mediterranean Region Countries
Amin Ataey, Elnaz Jafarvand, Davoud Adham, Eslam Moradi-Asl
J Prev Med Public Health. 2020;53(2):98-105.   Published online March 31, 2020
DOI: https://doi.org/10.3961/jpmph.19.100
  • 12,670 View
  • 278 Download
  • 72 Crossref
AbstractAbstract PDF
Objectives
Obesity is regarded as one of the most prominent health threats worldwide and a serious risk factor for non-communicable diseases, such as diabetes mellitus type 2, high blood pressure, cardiovascular diseases, and some types of cancer. Given the role that societal development—as reflected by the Human Development Index (HDI)—may play in the prevalence of obesity and overweight, this study aimed to investigate the degree to which the prevalence of obesity and overweight is affected by HDI and its components.
Methods
In this ecological study, the required data on HDI and its components were gathered from the latest report of the United Nations Development Program, and data on obesity and overweight were acquired from the latest reports published on the World Health Organization website. Statistical analyses were conducted using SPSS version 24.0.
Results
The prevalence of obesity was determined to be significantly higher among females than males, and the gross national index per capita was found to be significantly higher for males than females (p<0.05). Significant positive correlations were found between HDI and its components and sex, as well as indices of obesity and overweight.
Conclusions
A significant positive correlation exists between HDI and obesity. As policy-makers attempt to improve the general welfare of the people, they should be aware of potential unwanted effects of development on the risk of obesity and overweight among the population.
Summary

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Epidemiological Features of Human Cases After Bites/Scratches From Rabies-suspected Animals in Zenica-Doboj Canton, Bosnia and Herzegovina
Selma Uzunović, Muhamed Skomorac, Fatima Bašić, Ivona Mijač-Musić
J Prev Med Public Health. 2019;52(3):170-178.   Published online April 16, 2019
DOI: https://doi.org/10.3961/jpmph.18.252
  • 5,822 View
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AbstractAbstract PDF
Objectives
To determine the epidemiological features of patients and animals after bites/scratches from rabies-suspected animals in Zenica-Doboj Canton, Bosnia and Herzegovina.
Methods
Data from all patients (and the causative animals) admitted to the Antirabies Service of the Institute for Health and Food Safety Zenica in the 2009-2017 period were analyzed, including age, sex, anatomical site of the bite/scratch, animal type (stray/owned/wildlife), veterinary observations of the animal, and whether antirabies post-exposure prophylaxis (PEP) was indicated and/or administered.
Results
In total, 1716 patients were admitted. Bites/scratches were most frequently recorded during April and May (n=181, 10.5% and n=163, 9.5%, respectively). The persons admitted were mostly from the Zenica municipality (n=1278, 74.5%; incidence: 11.55/ 1000), which is 66.6% urbanized. Males were more frequently represented (n=1089, 63.6%). The patients were mostly 50-64 and 25-49 years of age (n=425, 24.7% and n=390, 22.7%, respectively). Dog bites were the most common cause (n=1634, 95.1%, of which n=1258, 77.0% were caused by stray dogs). PEP was indicated for 997 (58.1%) patients. Only 340 (19.9%) animals underwent veterinary observations (3.1% of stray and 76.1% of owned animals). The largest number of injuries were presented at lower extremities, 1044 (60.8%) cases.
Conclusions
Zenica-Doboj Canton is a rabies-free region. Due to the high rate of stray animals not undergoing veterinary observations, the non-existence of a unique dog registry, and the consequent lack of information about stray animals in terms of number, vaccination, neutering, and euthanasia, there is an urgent need for improving the prevention and control of rabies within the One Health framework.
Summary

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    Murat Solmaz, Özhan Orhan
    Anatolian Current Medical Journal.2024; 6(3): 229.     CrossRef
  • Dog bites as a zoonotic risk in Ecuador: Need for the implementation of a One Health approach
    G. Joselyn Calderón, Silvia Poveda, Ariana León Sosa, Naomi Mora, Manel López Bejar, Solón Alberto Orlando, Miguel Angel Garcia-Bereguiain
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    Carmen Luz Barrios, Carlos Bustos-López, Carlos Pavletic, Alonso Parra, Macarena Vidal, Jonathan Bowen, Jaume Fatjó
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Perspective
Introduction of Phylodynamics for Controlling the HIV/AIDS Epidemic in Korea
Jong-Myon Bae
J Prev Med Public Health. 2018;51(6):326-328.   Published online October 22, 2018
DOI: https://doi.org/10.3961/jpmph.18.150
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AbstractAbstract AbstractSummary PDFSupplementary Material
As over 1000 new cases of HIV/AIDS occur in Korea annually, preventive health programs against HIV/AIDS are urgently needed. Since phylodynamic studies have been suggested as a way to understand how infectious diseases are transmitted and evolve, phylodynamic inferences can be a useful tool for HIV/AIDS research. In particular, phylodynamic models are helpful for dating the origins of an epidemic and estimating its basic reproduction number. Thus, the introduction of phylodynamics would be a highly valuable step towards controlling the HIV/AIDS epidemic in Korea.
Summary
Korean summary
국내 HIV/AIDS 신환자가 지속적으로 발생하고 있는 상황에서, 다른 나라에서는 HIV 감염관리에 계통역동학을 적용하고 있다. 이는 감염원과 감염경로를 알아내고, 기본재생산지수를 산출하도록 해주기 때문이다. 따라서 국내 HIV/AIDS 관리를 위해 계통역동학 적용을 적극 제안한다.”
Original Articles
Malaria Risk Factors in Kaligesing, Purworejo District, Central Java Province, Indonesia: A Case-control Study
Pratiwi Cahyaningrum, Sulistyawati Sulistyawati
J Prev Med Public Health. 2018;51(3):148-153.   Published online May 16, 2018
DOI: https://doi.org/10.3961/jpmph.18.036
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  • 329 Download
  • 4 Crossref
AbstractAbstract PDF
Objectives
Malaria remains a public health concern worldwide, including Indonesia. Purworejo is a district in which endemic of malaria, they have re-setup to entering malaria elimination in 2021. Accordingly, actions must be taken to accelerate and guaranty that the goal will reach based on an understanding of the risk factors for malaria. Thus, we analysed malaria risk factors based on human and housing conditions in Kaligesing, Purworejo, Indonesia.
Methods
A case-control study was carried out in Kaligesing subdistrict, Purworejo, Indonesia in July to August 2017. A structured questionnaire and checklist were used to collect data from 96 participants, who consisted of 48 controls and 48 cases. Univariate, bivariate, and multivariate analyses were performed.
Results
Bivariate analysis found that education level, the presence of a cattle cage within 100 m of the house, not sleeping under a bednet the previous night, and not closing the doors and windows from 6 p.m. to 5 a.m. were significantly (p≤0.25) associated with malaria. Of these factors, only not sleeping under a bednet the previous night and not closing the doors and windows from 6 p.m. to 5 a.m. were significantly associated with malaria.
Conclusions
The findings of this study demonstrate that potential risk factor for Malaria should be paid of attention all the time, particularly for an area which is targeting Malaria elimination.
Summary

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    Noor Alis Setiyadi, Ira Handayani, Sayono Sayono, Tepanata Pumpaibool, Irfanul Chakim
    F1000Research.2022; 11: 1261.     CrossRef
  • Malaria risk factors in northern Namibia: The importance of occupation, age and mobility in characterizing high-risk populations
    Jennifer L. Smith, Davis Mumbengegwi, Erastus Haindongo, Carmen Cueto, Kathryn W. Roberts, Roly Gosling, Petrina Uusiku, Immo Kleinschmidt, Adam Bennett, Hugh J. Sturrock, Khin Thet Wai
    PLOS ONE.2021; 16(6): e0252690.     CrossRef
  • Malaria Risk Factors in Banjarnegara, Indonesia: A Matched Case-Control Study
    Sulistyawati SULISTYAWATI, Rokhmayanti ROKHMAYANTI, Fajar FATMAWATI
    Journal of UOEH.2020; 42(2): 161.     CrossRef
  • Risk Factors for Malaria Infection and Seropositivity in the Elimination Area of Grand’Anse, Haiti: A Case–Control Study among Febrile Individuals Seeking Treatment at Public Health Facilities
    Ruth A. Ashton, Vena Joseph, Lotus L. van den Hoogen, Kevin K. A. Tetteh, Gillian Stresman, Matt Worges, Thomas Druetz, Michelle A. Chang, Eric Rogier, Jean Frantz Lemoine, Chris Drakeley, Thomas P. Eisele
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Barriers to Health Service Utilization Among Iranian Female Sex Workers: A Qualitative Study
Mehran Asadi-Aliabadi, Jamileh Abolghasemi, Shahnaz Rimaz, Reza Majdzadeh, Fereshteh Rostami-Maskopaee, Effat Merghati-Khoei
J Prev Med Public Health. 2018;51(2):64-70.   Published online February 6, 2018
DOI: https://doi.org/10.3961/jpmph.17.174
  • 13,714 View
  • 320 Download
  • 14 Crossref
AbstractAbstract PDF
Objectives
In most countries around the world, sex work is an illegal activity. Female sex workers (FSWs) in Iran hide their identities, and they are known to be a hard-to-reach population. Despite free access to HIV testing, fewer than half of FSWs receive HIV testing. The purpose of this study was to characterize the reasons for which FSWs do not seek testing at drop-in centers (DICs) and voluntary counseling and testing (VCT) centers in Iran. Methods: A qualitative study was conducted in 2016. The participants were 24 FSWs who received services at VCT centers and DICs for vulnerable females in the north of Iran and 9 males who were the clients of FSWs. In this study, we made use of purposive sampling and carried out a thematic analysis. Results: We found 4 major and 6 minor themes. The major themes were: fear of being infected (with HIV), stigma, indifference, and knowledge. Conclusions: Despite the significant efforts made by the government of Iran to establish and expand DICs for vulnerable females, the number of FSWs receiving services at these centers has not been very considerable. Consequently, by introducing and implementing training programs for peer groups, it may be possible to take steps toward establishing strategic programs for the control and prevention of HIV/AIDS.
Summary

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  • HIV Treatment and Care of Adolescents: Perspectives of Adolescents on Community-Based Models in Northern Uganda
    Charles Miyingo, Teddy Mpayenda, Ruth Nyole, Joan Ayinembabazi, Mujib Ssepuuya, Eddie Marvin Ssebuwufu, Sean Steven Puleh, Samson Udho, Amir Kabunga
    HIV/AIDS - Research and Palliative Care.2023; Volume 15: 105.     CrossRef
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    Ali Asghar Firouzjaeian, Mansoureh Shifteh, Hadis Feli
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    Payam Roshanfekr, Leila Moftakhar, Sakineh Narouee, Delaram Ali, Meroe Vameghi, Christopher Fairley
    Sexual Health.2023; 20(4): 366.     CrossRef
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    Lydia Atuhaire, Constance S. Shumba, Peter S. Nyasulu
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    Nasim Sadat Hosseini Divkolaye, Javad Khalatbari, Marjan Faramarzi, Fariba Seighali, Shokoufeh Radfar, Ali ArabKhazaeli, Frederick M. Burkle
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    Yuxi Lin, Chuanxi Li, Lin Wang, Kedi Jiao, Wei Ma
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    Natasha Blumer, Lisa M. Pfadenhauer, Jacob Burns, Zixin Wang
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    Farzaneh Valizadeh, Abolfazl Mohammadbeigi, Reza Chaman, Fatemeh Kashefi, Ali Mohammad Nazari, Zahra Motaghi
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    Zahra Jorjoran Shushtari, Yahya Salimi, Seyed Ali Hosseini, Homeira Sajjadi, Tom A. B. Snijders
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    Javad Yoosefi Lebni, Seyed Fahim Irandoost, Ali Akbar Dehghan, Arash Ziapour, Bahar Khosravi, Nafiul Mehedi
    Heliyon.2021; 7(12): e08512.     CrossRef
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    I Gusti Ngurah Edi Putra, Pande Putu Januraga
    Tropical Medicine and Infectious Disease.2020; 5(2): 73.     CrossRef
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    Javad Yoosefi lebni, Seyed Fahim Irandoost, Arash Ziapour, Mohammad Ali Mohammadi Gharehghani, Farbod Ebadi Fard Azar, Goli Soofizad, Bahar Khosravi, Mahnaz Solhi
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  • The Effects of Socio-demographic Characteristics on Indonesian Women’s Knowledge of HIV/AIDS: A Cross-sectional Study
    Putu Erma Pradnyani, Arief Wibowo, Mahmudah
    Journal of Preventive Medicine and Public Health.2019; 52(2): 109.     CrossRef
  • Challenges of Seeking HIV Testing Among Marginalized Populations in Iran: A Letter to the Editor
    Mehran Rostami, Aboubakr Neshati-Khorram, Shahab Rezaeian
    International Journal of High Risk Behaviors and Addiction.2019;[Epub]     CrossRef
Avoidable Burden of Risk Factors for Serious Road Traffic Crashes in Iran: A Modeling Study
Fatemeh Khosravi Shadmani, Kamyar Mansori, Manoochehr Karami, Farid Zayeri, Reza Khosravi Shadman, Shiva Mansouri Hanis, Hamid Soori
J Prev Med Public Health. 2017;50(2):83-90.   Published online February 6, 2017
DOI: https://doi.org/10.3961/jpmph.16.085
  • 7,399 View
  • 240 Download
  • 1 Crossref
AbstractAbstract PDF
Objectives
The aim of this study was to model the avoidable burden of the risk factors of road traffic crashes in Iran and to prioritize interventions to reduce that burden.
Methods
The prevalence and the effect size of the risk factors were obtained from data documented by the traffic police of Iran in 2013. The effect size was estimated using an ordinal regression model. The potential impact fraction index was applied to calculate the avoidable burden in order to prioritize interventions. This index was calculated for theoretical, plausible, and feasible minimum risk level scenarios. The joint effects of the risk factors were then estimated for all the scenarios.
Results
The highest avoidable burdens in the theoretical, plausible, and feasible minimum risk level scenarios for the non-use of child restraints on urban roads were 52.25, 28.63, and 46.67, respectively. In contrast, the value of this index for speeding was 76.24, 37.00, and 62.23, respectively, for rural roads.
Conclusions
On the basis of the different scenarios considered in this research, we suggest focusing on future interventions to decrease the prevalence of speeding, the non-use of child restraints, the use of cell phones while driving, and helmet disuse, and the laws related to these items should be considered seriously.
Summary

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  • Safe Traffic Behaviors in Adolescents: A Cross-sectional Study Based on the Theory of Planned Behavior
    Alireza Shahab Jahanlou, Laleh Hassani, Vahid Ranaei, Ghodratollah Roshanaei, Sonja Forward, Kristin Haglund, Forouzan Rezapur-Shahkolai
    Iranian Journal of Psychiatry and Behavioral Sciences.2022;[Epub]     CrossRef
Food Security in Households of People Living With Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome: A Cross-sectional Study in a Subdivision of Darjeeling District, West Bengal
Pallabi Dasgupta, Sharmistha Bhattacherjee, Dilip Kumar Das
J Prev Med Public Health. 2016;49(4):240-248.   Published online July 19, 2016
DOI: https://doi.org/10.3961/jpmph.16.023
  • 9,215 View
  • 150 Download
  • 8 Crossref
AbstractAbstract PDF
Objectives
Human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) adversely impacts food security in households of people living with HIV/AIDS (PLWHA). Little research has focused on food insecurity among PLWHA in India. The purpose of this study was to identify the prevalence of and factors relating to food security in households of PLWHA in the Siliguri subdivision of Darjeeling, West Bengal, India.
Methods
A cross-sectional community-based study was carried out among 173 PLWHA residing in Siliguri and registered at the Anti-retroviral Therapy Centre of North Bengal Medical College & Hospital. Data was collected at the household level with interviews of PLWHA using a food security survey instrument. We analyzed the associations using logistic regression.
Results
The prevalence of household food security among the participants was 50.9% (88/173). Five years or more of schooling, higher socioeconomic class and males were found to be significantly associated with a higher likelihood of food security. A later stage of the disease and the presence of other family members with HIV/AIDS were significantly associated with a lower likelihood of food security. The major coping strategies to deal with food insecurity in the acute phase HIV infection included borrowing money (56.1%), followed by spousal support, loans from microfinance institutions, banks, or money lenders, borrowing food, or selling agricultural products.
Conclusions
The present study revealed that only about half of households with PLWHA were food secure. Prior interventions relating to periods of food and economic crisis as well as strategies for sustaining food security and economic status are needed in this area.
Summary

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Special Article
Methylmercury Exposure and Health Effects
Young-Seoub Hong, Yu-Mi Kim, Kyung-Eun Lee
J Prev Med Public Health. 2012;45(6):353-363.   Published online November 29, 2012
DOI: https://doi.org/10.3961/jpmph.2012.45.6.353
  • 27,092 View
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  • 274 Crossref
AbstractAbstract PDF

Methylmercury is a hazardous substance that is of interest with regard to environmental health, as inorganic mercury circulating in the general environment is dissolved into freshwater and seawater, condensed through the food chain, ingested by humans, and consequently affects human health. Recently, there has been much interest and discussion regarding the toxicity of methylmercury, the correlation with fish and shellfish intake, and methods of long-term management of the human health effects of methylmercury. What effects chronic exposure to a low concentration of methylmercury has on human health remains controversial. Although the possibility of methylmercury poisoning the heart and blood vessel system, the reproductive system, and the immune system is continuously raised and discussed, and the carcinogenicity of methylmercury is also under discussion, a clear conclusion regarding the human health effects according to exposure level has not yet been drawn. The Joint FAO/WHO Expert Committee on Food Additives proposed to prepare additional fish and shellfish intake recommendations for consumers based on the quantified evaluation of the hazardousness of methylmercury contained in fish and shellfish, methylmercury management in the Korea has not yet caught up with this international trend. Currently, the methylmercury exposure level of Koreans is known to be very high. The starting point of methylmercury exposure management is inorganic mercury in the general environment, but food intake through methylation is the main exposure source. Along with efforts to reduce mercury in the general environment, food intake management should be undertaken to reduce the human exposure to methylmercury in Korea.

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Brief Communication
An Outbreak of Novel Influenza A (H1N1) in the English Language Institute.
Joon Hyung Kim, Han Sung Lee, Hye Kyung Park, Jin Seok Kim, Sang Won Lee, Seong Sun Kim, Jong Koo Lee
J Prev Med Public Health. 2010;43(3):274-278.
DOI: https://doi.org/10.3961/jpmph.2010.43.3.274
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AbstractAbstract PDF
OBJECTIVES
This report describes the results of an investigation on an outbreak of novel influenza A (H1N1) in an English language Institute in Seoul, Korea in May 2009. METHODS: In this outbreak, novel influenza A (H1N1) was confirmed in 22 of 91 trainees, trainers and staff members. The trainees and 2 staff members were isolated in an assigned facility and the rest were isolated in their homes after we discovered the first patient with novel influenza A (H1N1). After the isolation, the people in the assigned facility were educated to use N95 respirators and they received oseltamivir for prophylaxis. RESULTS: The initial findings in this study suggest that the symptoms were mild and similar to those of seasonal influenza. The classmates and roommates of the infected patients were more likely to get infected with novel influenza A (H1N1) than the trainees who were not classmates or roommates of the patients (OR: 3.19, 95% CI=0.91 - 11.11 for classmates and OR: 40.0, 95% CI=7.4-215.7 for roommates). CONCLUSIONS: The public health response seems successful in terms of preventing the spread of this virus into the local community.
Summary

Citations

Citations to this article as recorded by  
  • In-Flight Transmission of Novel Influenza A (H1N1)
    Joon Hyung Kim, Dong-Han Lee, Sang-Sook Shin, Chun Kang, Jin Seok Kim, Byung Yool Jun, Jong-Koo Lee
    Epidemiology and Health.2010; 32: e2010006.     CrossRef
English Abstracts
'Informed Consent' in Public Health Activities: Based on the Universal Declaration on Bioethics and Human Rights, UNESCO.
Kwang Ho Meng
J Prev Med Public Health. 2008;41(5):339-344.
DOI: https://doi.org/10.3961/jpmph.2008.41.5.339
  • 4,327 View
  • 114 Download
  • 2 Crossref
AbstractAbstract PDF
OBJECTIVES
The objective of this paper is to discuss the importance of obtaining informed consent for conducting epidemiological studies and public health activities, based on the Report of the UNESCO's Working Group on Informed Consent. METHODS: The Report of the UNESCO's Working Group on Informed Consent was reviewed and discussed in connection with the ethical considerations of public health activities and epidemiological research. RESULTS: It was at the Nuremberg Trial for the German war criminals of the Second World War that the principle of 'consent' was first stated as a consequence of the medical abuses carried out during the War. As a result of the Trial, the Nuremberg Code came out in 1947. Since then, various international declarations or ethical principles on 'informed consent' have been developed and published. These ethical principles on 'informed consent' have mostly to do with the clinical research that involves human subjects, and not with epidemiological studies and public health activities. However, UNESCO recently issued a comprehensive Report on Informed Consent based on the Universal Declaration on Bioethics and Human Rights adopted in 2005, and this included detailed guidelines on informed consent in epidemiological studies and public health activities. CONCLUSIONS: Universal Declaration on Bioethics and Human Rights emphasizes the principle of autonomy to protect the human rights of the human subjects involved in any public health activities and epidemiological research. As a practical guideline, obtaining informed consent is strongly recommended.
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Citations

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    BMC Public Health.2010;[Epub]     CrossRef
Strategy Considerations in Genome Cohort Construction in Korea.
Joohon Sung, Sung Il Cho
J Prev Med Public Health. 2007;40(2):95-101.
DOI: https://doi.org/10.3961/jpmph.2007.40.2.95
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AbstractAbstract PDF
Focusing on complex diseases of public health significance, strategic issues regarding the on-going Korean Genome Cohort were reviewed: target size and diseases, measurements, study design issues, and followup strategy of the cohort. Considering the epidemiologic characteristics of Korean population as well as strengths and drawbacks of current research environment, we tried to tailor the experience of other existing cohorts into proposals for this Korean study. Currently 100,000 individuals have been participating the new Genome Cohort in Korea. Target size of de novo collection is recommended to be set as between 300,000 to 500,000. This target size would allow acceptable power to detect genetic and environmental factors of moderate effect size and possible interactions between them. Family units and/or special subgroups are recommended to parallel main body of adult individuals to increase the overall efficiency of the study. Given that response rate to the conventional re-contact method may not be satisfactory, successful follow-up is the main key to the achievement of the Korean Genome Cohort. Access to the central database such as National Health Insurance data can provide enormous potential for near-complete case detection. Efforts to build consensus amongst scientists from broad fields and stakeholders are crucial to unleash the centralized database as well as to refine the commitment of this national project.
Summary

JPMPH : Journal of Preventive Medicine and Public Health