Journal of Preventive Medicine and Public Health

Volume 44(3); May 2011

Special Article

Cost Effectiveness of Interventions to Promote Screening for Colorectal Cancer: A Randomized Trial: Swati Misra, David R. Lairson, Wenyaw Chan, Yu-Chia Chang, L. Kay Bartholomew, Anthony Greisinger, Amy McQueen, Sally W. Vernon; J Prev Med Public Health. 2011;44(3):101-110. Published online May 17, 2010; DOI: https://doi.org/10.3961/jpmph.2011.44.3.101

12,690 View
98 Download
15 Crossref

Objectives

Screening for colorectal cancer is considered cost effective, but is underutilized in the U.S. Information on the efficiency of "tailored interventions" to promote colorectal cancer screening in primary care settings is limited. The paper reports the results of a cost effectiveness analysis that compared a survey-only control group to a Centers for Disease Control (CDC) web-based intervention (screen for life) and to a tailored interactive computer-based intervention.

Methods

A randomized controlled trial of people 50 and over, was conducted to test the interventions. The sample was 1224 partcipants 50-70 years of age, recruited from Kelsey-Seybold Clinic, a large multi-specialty clinic in Houston, Texas. Screening status was obtained by medical chart review after a 12-month follow-up period. An "intention to treat" analysis and micro costing from the patient and provider perspectives were used to estimate the costs and effects. Analysis of statistical uncertainty was conducted using nonparametric bootstrapping.

Results

The estimated cost of implementing the web-based intervention was $40 per person and the cost of the tailored intervention was $45 per person. The additional cost per person screened for the web-based intervention compared to no intervention was $2602 and the tailored intervention was no more effective than the web-based strategy.

Conclusions

The tailored intervention was less cost-effective than the web-based intervention for colorectal cancer screening promotion. The web-based intervention was less cost-effective than previous studies of in-reach colorectal cancer screening promotion. Researchers need to continue developing and evaluating the effectiveness and cost-effectiveness of interventions to increase colorectal cancer screening.

Summary

Citations

Citations to this article as recorded by

Extending analytic methods for economic evaluation in implementation science
Meghan C. O’Leary, Kristen Hassmiller Lich, Leah Frerichs, Jennifer Leeman, Daniel S. Reuland, Stephanie B. Wheeler
Implementation Science.2022;[Epub] CrossRef
Interventions for increasing colorectal cancer screening uptake among African-American men: A systematic review and meta-analysis
Charles R. Rogers, Phung Matthews, Lei Xu, Kenneth Boucher, Colin Riley, Matthew Huntington, Nathan Le Duc, Kola S. Okuyemi, Margaret J. Foster, Joseph Telfair
PLOS ONE.2020; 15(9): e0238354. CrossRef
Economic Evaluation of Tailored Web versus Tailored Telephone-Based Interventions to Increase Colorectal Cancer Screening among Women
David R. Lairson, Tong Han Chung, Danmeng Huang, Timothy E. Stump, Patrick O. Monahan, Shannon M. Christy, Susan M. Rawl, Victoria L. Champion
Cancer Prevention Research.2020; 13(3): 309. CrossRef
Economics of Multicomponent Interventions to Increase Breast, Cervical, and Colorectal Cancer Screening: A Community Guide Systematic Review
Giridhar Mohan, Sajal K. Chattopadhyay, Donatus U. Ekwueme, Susan A. Sabatino, Devon L. Okasako-Schmucker, Yinan Peng, Shawna L. Mercer, Anilkrishna B. Thota
American Journal of Preventive Medicine.2019; 57(4): 557. CrossRef
Colorectal cancer screening interventions in 2 health care systems serving disadvantaged populations: Screening uptake and cost‐effectiveness
Christen L. Lara, Kelly L. Means, Krystal D. Morwood, Westley R. Lighthall, Sonja Hoover, Florence K.L. Tangka, Cynthia French, Krystal D. Gayle, Amy DeGroff, Sujha Subramanian
Cancer.2018; 124(21): 4130. CrossRef
The cost of implementing two small media interventions to promote HPV vaccination
Siddharth S. Karanth, David R. Lairson, Danmeng Huang, Lara S. Savas, Sally W. Vernon, María E. Fernández
Preventive Medicine.2017; 99: 277. CrossRef
An Economic Evaluation of Colorectal Cancer Screening in Primary Care Practice
Richard T. Meenan, Melissa L. Anderson, Jessica Chubak, Sally W. Vernon, Sharon Fuller, Ching-Yun Wang, Beverly B. Green
American Journal of Preventive Medicine.2015; 48(6): 714. CrossRef
Optimising colorectal cancer screening acceptance: a review
Carlo Senore, John Inadomi, Nereo Segnan, Cristina Bellisario, Cesare Hassan
Gut.2015; 64(7): 1158. CrossRef
Get Screened: A Randomized Trial of the Incremental Benefits of Reminders, Recall, and Outreach on Cancer Screening
Robert J. Fortuna, Amna Idris, Paul Winters, Sharon G. Humiston, Steven Scofield, Samantha Hendren, Patricia Ford, Shirley X. L. Li, Kevin Fiscella
Journal of General Internal Medicine.2014; 29(1): 90. CrossRef
Public Awareness of Colorectal Cancer Screening: Knowledge, Attitudes, and Interventions for Increasing Screening Uptake
Antonio Z. Gimeno Garcia, Noemi Hernandez Alvarez Buylla, David Nicolas-Perez, Enrique Quintero
ISRN Oncology.2014; 2014: 1. CrossRef
Cost‐effectiveness of a standard intervention versus a navigated intervention on colorectal cancer screening use in primary care
David R. Lairson, Melissa DiCarlo, Ashish A. Deshmuk, Heather B. Fagan, Randa Sifri, Nora Katurakes, James Cocroft, Jocelyn Sendecki, Heidi Swan, Sally W. Vernon, Ronald E. Myers
Cancer.2014; 120(7): 1042. CrossRef
Communication preference moderates the effect of a tailored intervention to increase colorectal cancer screening among African Americans
Ken Resnicow, Yan Zhou, Sarah Hawley, Masahito Jimbo, Mack T. Ruffin, Rachel E. Davis, Deirdre Shires, Jennifer Elston Lafata
Patient Education and Counseling.2014; 97(3): 370. CrossRef
A lesson in business: cost-effectiveness analysis of a novel financial incentive intervention for increasing physical activity in the workplace
Mary Anne T Dallat, Ruth F Hunter, Mark A Tully, Karen J Cairns, Frank Kee
BMC Public Health.2013;[Epub] CrossRef
Personalised risk communication for informed decision making about taking screening tests
Adrian GK Edwards, Gurudutt Naik, Harry Ahmed, Glyn J Elwyn, Timothy Pickles, Kerry Hood, Rebecca Playle
Cochrane Database of Systematic Reviews.2013;[Epub] CrossRef
Colorectal Cancer in the Kingdom of Saudi Arabia: Need for Screening
Mahmoud H. Mosli, Mahmoud S. Al-Ahwal
Asian Pacific Journal of Cancer Prevention.2012; 13(8): 3809. CrossRef

Original Articles

Changes in the Distribution of Maternal Age and Parity and Increasing Trends in the Low Birth Weight Rate in Korea Between 1995 and 2005: Jisuk Bae, Jung Han Park, Yoo Keun Park, Jong-Yeon Kim, Sang-Won Lee, Soon-Woo Park; J Prev Med Public Health. 2011;44(3):111-117. Published online May 17, 2010; DOI: https://doi.org/10.3961/jpmph.2011.44.3.111

8,974 View
76 Download
10 Crossref

Abstract PDF

Objectives

This study measured the impact of shifts in maternal age and parity on the increase in the low birth weight (LBW) rate in Korea.

Methods

We obtained raw data for all 6 397 945 live births registered at the Korea National Statistical Office between 1995 and 2005. We calculated the proportion of increment in the LBW rate due to changes in the distribution of maternal age and parity (AP-dis) and the proportion due to changes in the age- and parity-specific LBW rate (AP-spe).

Results

The LBW rate increased from 3.02% in 1995 to 4.28% in 2005. The multiple birth rate increased from 1.32% to 2.19% during the same period. Of the 1.26% points increment in the LBW rate, 0.64% points occurred among singleton births and 0.62% points occurred among multiple births. Changes in the AP-dis accounted for 50% of the increase in the LBW rate among singleton births, but did not contribute to the increase in the LBW rate among multiple births. The remainder of the total increment in the LBW rate was explained by the increase in the AP-spe.

Conclusions

This study demonstrated that shifts in maternal age and parity among singleton births and increased multiple births were important contributors to the increment in the LBW rate. This study also revealed that the increase in the AP-spe was an equally important contributor as the shifts in maternal age and parity to the increment in the LBW rate among singleton births and was a major contributor among multiple births.

Summary

Citations

Citations to this article as recorded by

Incidence, Long-Term Visual Outcomes, and Mortality in Retinopathy of Prematurity in Korea: A Nationwide Population-Based Study
Kun-Hoo Na, Kyoung Hoon Kim, Tae Uk Kang, Hoo Jae Hann, Hyeong Sik Ahn, Hyun Jung Kim
Investigative Opthalmology & Visual Science.2020; 61(10): 14. CrossRef
Factors associated with low birth weight at term: a population-based linkage study of the 100 million Brazilian cohort
Ila R. Falcão, Rita de Cássia Ribeiro-Silva, Marcia F. de Almeida, Rosemeire L. Fiaccone, Aline dos S. Rocha, Naiá Ortelan, Natanael J. Silva, Enny S. Paixao, Maria Yury Ichihara, Laura C. Rodrigues, Mauricio L. Barreto
BMC Pregnancy and Childbirth.2020;[Epub] CrossRef
Modeling the Effect of Mother's Characteristics on the Weight of a Newborn
Oluwafemi Samson Balogun, Donald Douglas Atsa'am, Toluwalase Janet Akingbade, Emmanuel Awuni Kolog, Richard O. Agjei, Samuel Nii Odoi Devine
International Journal of Childbirth.2020; 10(4): 206. CrossRef
Impact of Changes in Maternal Age and Parity Distribution on the Increasing Trends in the Low Birth Weight and Very Low Birth Weight Rates in South Korea, 2005-2015
Yujin Oh, Jisuk Bae
Journal of Preventive Medicine and Public Health.2019; 52(2): 123. CrossRef
Factors Associated With Failure to Thrive Among Children Aged 3 to 72 Months in Jahrom, Southern Iran
Vahid Rahmanian, Yaser Sarikhani, Keramatollah Rahmanian, Elham Mansoorian, Mahdieh Zare
Shiraz E-Medical Journal.2018;[Epub] CrossRef
Adverse Child’s Birth Outcomes and Maternal Age at Birth: 1997-98, 2014-15 Birth Certificate Data of Korea
Sang Hwa Park, Jong Seok Kim, Dar Oh Lim
Journal of Health Informatics and Statistics.2017; 42(3): 294. CrossRef
Experiences of Prenatal Genetic Screening and Diagnostic Testing Among Pregnant Korean Women of Advanced Maternal Age
Myunghee Jun, Vipavee Thongpriwan, Kyung Sook Choi
Journal of Transcultural Nursing.2017; 28(6): 550. CrossRef
Reproductive Health of Women in Rural Areas of East Azerbaijan – Iran, before and after Implementation of rural Family Physician Program: an Ecologic Study
Mahasti Alizadeh, Hossein Jabbari Birami, Siavash Moradi
Journal of Caring Sciences.2015; 4(4): 321. CrossRef
Risk Assessment of Adverse Birth Outcomes in Relation to Maternal Age
Yi-Hao Weng, Chun-Yuh Yang, Ya-Wen Chiu, Lynette K. Rogers
PLoS ONE.2014; 9(12): e114843. CrossRef
The association between maternal nonylphenol exposure and parity on neonatal birth weight: A cohort study in Taiwan
Chia-Huang Chang, Mei-Lien Chen, Kai-Wei Liao, Yen-An Tsai, I-Fang Mao, Tzu-Hao Wang, Shiaw-Min Hwang, Yu-Jen Chang, Ming-Song Tsai
Chemosphere.2013; 93(6): 1145. CrossRef

Modifying Effect of Suicidal Ideation on the Relationship Between Asthma and Cigarette Use Behaviors Among Korean Adolescents: Jisuk Bae, Eun Young Park, Soon-Woo Park; J Prev Med Public Health. 2011;44(3):118-124. Published online May 17, 2010; DOI: https://doi.org/10.3961/jpmph.2011.44.3.118

7,965 View
63 Download
5 Crossref

Abstract PDF

Objectives

Although cigarette smoking is known to be related to the exacerbation of asthma symptoms, several studies have indicated that the prevalence of cigarette smoking among asthmatic adolescents is similar to or even higher than that among non-asthmatic adolescents. The aim of this study was to evaluate the relationship between asthma and cigarette use behaviors and whether or not the presence of suicidal ideation modifies this relationship among Korean adolescents.

Methods

We analyzed data from the 2008 Korea Youth Risk Behavior Web-based Survey, which included a nationally representative sample of middle and high school students. Multiple logistic regression models were used to calculate odd ratios and 95% confidence intervals of cigarette use behaviors among current asthmatics, former asthmatics, and non-asthmatics, after adjusting for gender, grade, school records, socioeconomic status, current alcohol use, and suicidal ideation.

Results

Of 75 238 study participants, 3.5% were current asthmatics and 4.5% were former asthmatics. Compared with non-asthmatics, asthmatics were more likely to report current cigarette use, frequent and heavy cigarette use, and cigarette use before 13 years of age. There were statistically significant interactions between asthma and suicidal ideation in cigarette use behaviors.

Conclusions

This study demonstrated that asthmatic adolescents are more likely than non-asthmatic adolescents to engage in cigarette use behaviors and the presence of suicidal ideation is an effect modifier of the relationship between asthma and cigarette use behaviors. Particular attention should be paid to the awareness of health risks of cigarette smoking and mental health problems among asthmatic adolescents.

Summary

Citations

Citations to this article as recorded by

Asthme et comportements suicidaires chez les adolescents: revue systématique
M. Underner, G. Peiffer, J. Perriot, I. De Chazeron, N. Jaafari
Revue des Maladies Respiratoires.2022; 39(4): 344. CrossRef
Association between Asthma and Suicidality in 9–12-Year-Old Youths
Kevin W. Hoffman, Elina Visoki, Stirling T. Argabright, Laura M. Schultz, Grace E. Didomenico, Kate T. Tran, Joshua H. Gordon, Barbara H. Chaiyachati, Tyler M. Moore, Laura Almasy, Ran Barzilay
Brain Sciences.2022; 12(12): 1602. CrossRef
Suicidality among patients with asthma: A systematic review and meta-analysis
Yan Zhang, Jun Cheng, Yuanyuan Li, Ruoxi He, Abira A Choudhry, Juan Jiang, Pinhua Pan, Xiaoli Su, Chengping Hu
Journal of Affective Disorders.2019; 256: 594. CrossRef
Asthma and other allergic diseases in relation to suicidal behavior among South Korean adolescents
Chang Hoon Han, Jae Ho Chung
Journal of Psychosomatic Research.2018; 115: 94. CrossRef
The relationship between asthma and suicidal behaviours: a systematic literature review
Emma Barker, Kairi Kõlves, Diego De Leo
European Respiratory Journal.2015; 46(1): 96. CrossRef

Association Between MicroRNA196a2 rs11614913 Genotypes and the Risk of Non-Small Cell Lung Cancer in Korean Population: Young-Seoub Hong, Ho-Jin Kang, Jong-Young Kwak, Byung Lae Park, Chang-Hun You, Yu-Mi Kim, Heon Kim; J Prev Med Public Health. 2011;44(3):125-130. Published online May 17, 2010; DOI: https://doi.org/10.3961/jpmph.2011.44.3.125

10,129 View
103 Download
33 Crossref

Abstract PDF

Objectives

The microRNA (miRNA) miR-196a2 may play an important role in lung cancer development and survival by altering binding activity of target mRNA. In this study, we evaluated their associations with the susceptibility of non-small cell lung cancers (NSCLC) by case-control study in a Korean population.

Methods

We performed genotyping analyses for miR-196a2 rs11614913 T/C at miRNA regions in a case-control study using blood samples of 406 NSCLC patient and 428 cancer-free control groups.

Results

The total C allele frequencies for miR-196a2 were 48.8% for the patients and 45.6% for the controls; and the genotype frequencies of TT, TC, and CC were 23.7%, 55.2%, and 21.1% for the patients and 31.1%, 46.35%, and 22.4% for the controls (p<0.05). Participants who possesses TC/CC genotypes showed high risk for NSCLC compared to those possessed TT genotypes (OR, 1.42; 95% CI, 1.03 to 1.96). The association was persisted in 60 and older age group, male, smokers, those without family history for cancer. However, no significant association of CC genotypes in recessive genetic model was observed.

Conclusions

In conclusion, this case-control study provides evidence that miR-196a2 rs11614913 C/T polymorphisms are associated with a significantly increased risk of NSCLC in a dominant model, indicating that common genetic polymorphisms in miR-196a2 rs11614913 are associated with NSCLC. The association of miR196a2 rs11614913 polymorphisms and NSCLC risk require confirmation through additional larger studies.

Summary

Citations

Citations to this article as recorded by

MiRNA-423 rs6505162 and miRNA-6811 rs2292879 SNP associated with lung cancer in Hainan, China
Jing Zhou, Chong Meng, Yixuan Li, Yihui Fu, Wenfang Long, Hairong Huang, Yunru Liu, Pengfei Lyu, Sha Xiao
Bioscience Reports.2023;[Epub] CrossRef
Molecular basis of sex differences in cancer: Perspective from Asia
Eric David Ornos, Leslie Faye Cando, Charlene Divine Catral, Elgin Paul Quebral, Ourlad Alzeus Tantengco, Ma. Veronica Pia Arevalo, Edward Christopher Dee
iScience.2023; 26(7): 107101. CrossRef
Effect of miR-196a2 rs11614913 Polymorphism on Cancer Susceptibility: Evidence From an Updated Meta-Analysis
Md. Abdul Aziz, Tahmina Akter, Mohammad Safiqul Islam
Technology in Cancer Research & Treatment.2022; 21: 153303382211097. CrossRef
Authors’ reply to Jayaraj et al. ‘s Letter to the Editor re: MIR196A2 rs11614913 contributes to susceptibility to colorectal cancer in Iranian population: A multi-center case-control study and meta-analysis
Monir Sadat Haerian, Batoul Sadat Haerian, Saadat Molanaei, Farid Kosari, Shahram Sabeti, Farahnaz Bidari-zerehpoosh, Ebrahim Abdolali
Gene.2021; 801: 145849. CrossRef
Characteristics of miRNA-SNPs in healthy Japanese subjects and non-small cell lung cancer, colorectal cancer, and soft tissue sarcoma patients
Koki Katayama, Shimon Nakashima, Hiroo Ishida, Yutaro Kubota, Masataka Nakano, Tatsuki Fukami, Yasutsuna Sasaki, Ken-ichi Fujita, Miki Nakajima
Non-coding RNA Research.2021; 6(3): 123. CrossRef
The Molecular Analysis of rs11614913 Polymorphism from miRNA196a Gene and Its Relationship with TNF-α Gene Expression in Cervical Cancer
Ahmad Hamta, Fatemeh Hajihassani
Jentashapir Journal of Cellular and Molecular Biology.2020;[Epub] CrossRef
Association of mir-196a-2 rs11614913 and mir-149 rs2292832 Polymorphisms With Risk of Cancer: An Updated Meta-Analysis
Jalal Choupani, Ziba Nariman-Saleh-Fam, Zahra Saadatian, Elaheh Ouladsahebmadarek, Andrea Masotti, Milad Bastami
Frontiers in Genetics.2019;[Epub] CrossRef
Impacts of single nucleotide polymorphisms in three microRNAs (miR-146a, miR-196a2 and miR-499) on the susceptibility to cervical cancer among Indian women
Nisha Thakur, Pallavi Singhal, Ravi Mehrotra, Mausumi Bharadwaj
Bioscience Reports.2019;[Epub] CrossRef
Micro-RNA 196a2 expression and miR-196a2 (rs11614913) polymorphism in T1DM: a pilot study
Alshaymaa A. Ibrahim, Abeer Ramadan, Aliaa Ahmed Wahby, Mirhane Hassan, Hend M. Soliman, Tamer A. Abdel Hamid
Journal of Pediatric Endocrinology and Metabolism.2019; 32(10): 1171. CrossRef
MIR196A2 rs11614913 C > T polymorphism correlates with an increased risk of hepatopulmonary syndrome in liver cirrhosis: a case–control study in China
Hai‐Yong Chen, Yao‐Min Chen, Jian Wu, Fu‐Chun Yang, Zhen Lv, Xiao‐Feng Xu, Shu‐Sen Zheng, Sang‐Sang Liao, Yi‐Hui Luo
Hepatology Research.2017; 47(8): 793. CrossRef
Association of miR-196a2 rs11614913 and miR-499 rs3746444 polymorphisms with cancer risk: a meta-analysis
Wanjun Yan, Xiaoyan Gao, Shuqun Zhang
Oncotarget.2017; 8(69): 114344. CrossRef
MiR-196a2 and lung cancer in Chinese non-smoking females: a genetic association study and expression analysis
Zhihua Yin, Zhigang Cui, Yangwu Ren, Lingzi Xia, Hang Li, Baosen Zhou
Oncotarget.2017; 8(41): 70890. CrossRef
Somatic Mutation of the SNP rs11614913 and Its Association with Increased MIR 196A2 Expression in Breast Cancer
Huanhuan Zhao, Jingman Xu, Dan Zhao, Meijuan Geng, Haize Ge, Li Fu, Zhengmao Zhu
DNA and Cell Biology.2016; 35(2): 81. CrossRef
MicroRNA-196a2 Biomarker and Targetome Network Analysis in Solid Tumors
Eman A. Toraih, Manal S. Fawzy, Eman A. Mohammed, Mohammad H. Hussein, Mohamad M. EL-Labban
Molecular Diagnosis & Therapy.2016; 20(6): 559. CrossRef
MicroRNA Gene Polymorphisms in Evaluating Therapeutic Efficacy After Transcatheter Arterial Chemoembolization for Primary Hepatocellular Carcinoma
Guang-Ping Qiu, Jie Liu
Genetic Testing and Molecular Biomarkers.2016; 20(10): 579. CrossRef
Individualized medicine enabled by genomics in Saudi Arabia
Muhammad Abu-Elmagd, Mourad Assidi, Hans-Juergen Schulten, Ashraf Dallol, Peter Natesan Pushparaj, Farid Ahmed, Stephen W Scherer, Mohammed Al-Qahtani
BMC Medical Genomics.2015;[Epub] CrossRef
Functional genetic variants in pre-miR-146a and 196a2 genes are associated with risk of lung cancer in North Indians
Kushaldeep Kaur Sodhi, Charu Bahl, Navneet Singh, Digamber Behera, Siddharth Sharma
Future Oncology.2015; 11(15): 2159. CrossRef
Quantitative assessment of the association between miR-196a2 rs11614913 polymorphism and cancer risk: evidence based on 45,816 subjects
Zhengjun Kang, Yuhui Li, Xiaokai He, Tao Jiu, Jinxing Wei, Fengyan Tian, Chaohui Gu
Tumor Biology.2014; 35(7): 6271. CrossRef
Effects of four single nucleotide polymorphisms in microRNA-coding genes on lung cancer risk
Xiaohong Fan, Zhijun Wu
Tumor Biology.2014; 35(11): 10815. CrossRef
Two functional polymorphisms in microRNAs and lung cancer risk: a meta-analysis
Gang Wang, Wulong Wang, Wenbin Gao, Jinyan Lv, Jinnv Fang
Tumor Biology.2014; 35(3): 2693. CrossRef
Effects of common polymorphisms rs2910164 in miR-146a and rs11614913 in miR-196a2 on susceptibility to colorectal cancer: a systematic review meta-analysis
D. Wan, W. Gu, G. Xu, C. Shen, D. Ding, S. Shen, S. Wang, X. Gong, S. He, Q. Zhi
Clinical and Translational Oncology.2014; 16(9): 792. CrossRef
Association Analysis of Single Nucleotide Polymorphisms in miR-146a and miR-196a2 on the Prevalence of Cancer in Elderly Japanese: A Case-Control Study
Cuneyd Parlayan, Shinobu Ikeda, Noriko Sato, Motoji Sawabe, Masaaki Muramatsu, Tomio Arai
Asian Pacific Journal of Cancer Prevention.2014; 15(5): 2101. CrossRef
Effects of Common Polymorphism rs11614913 in Hsa-miR-196a2 on Lung Cancer Risk
Zhengrong Yuan, Xu Zeng, Dan Yang, Weilu Wang, Zhihua Liu, Giuseppe Viglietto
PLoS ONE.2013; 8(4): e61047. CrossRef
Polymorphisms of microRNA Sequences or Binding Sites and Lung Cancer: A Meta-Analysis and Systematic Review
Zhiwei Chen, Ling Xu, Xiangyun Ye, Shengping Shen, Ziming Li, Xiaomin Niu, Shun Lu, Ramon Andrade de Mello
PLoS ONE.2013; 8(4): e61008. CrossRef
Association between microRNA Polymorphisms and Cancer Risk Based on the Findings of 66 Case-Control Studies
Xiao Pin Ma, Ting Zhang, Bo Peng, Long Yu, De Ke Jiang, Georgina L. Hold
PLoS ONE.2013; 8(11): e79584. CrossRef
Different Effects of Three Polymorphisms in MicroRNAs on Cancer Risk in Asian Population: Evidence from Published Literatures
Yeqiong Xu, Ling Gu, Yuqin Pan, Rui Li, Tianyi Gao, Guoqi Song, Zhenlin Nie, Liping Chen, Shukui Wang, Bangshun He, Sadashiva Karnik
PLoS ONE.2013; 8(6): e65123. CrossRef
Opportunities and Challenges for Selected Emerging Technologies in Cancer Epidemiology: Mitochondrial, Epigenomic, Metabolomic, and Telomerase Profiling
Mukesh Verma, Muin J. Khoury, John P.A. Ioannidis
Cancer Epidemiology, Biomarkers & Prevention.2013; 22(2): 189. CrossRef
The association of miR-146a rs2910164 and miR-196a2 rs11614913 polymorphisms with cancer risk: a meta-analysis of 32 studies
Jianbo Wang, Qingwei Wang, Hong Liu, Na Shao, Bingxu Tan, Guangyu Zhang, Kai Wang, Yibin Jia, Wei Ma, Nana Wang, Yufeng Cheng
Mutagenesis.2012; 27(6): 779. CrossRef
Mechanistic Roles of Noncoding RNAs in Lung Cancer Biology and Their Clinical Implications
Katey S. S. Enfield, Larissa A. Pikor, Victor D. Martinez, Wan L. Lam
Genetics Research International.2012; 2012: 1. CrossRef
A Genetic Variant in miR-196a2 Increased Digestive System Cancer Risks: A Meta-Analysis of 15 Case-Control Studies
Jing Guo, Mingjuan Jin, Mingwu Zhang, Kun Chen, Brock C. Christensen
PLoS ONE.2012; 7(1): e30585. CrossRef
Comprehensive Review of Genetic Association Studies and Meta-Analyses on miRNA Polymorphisms and Cancer Risk
Kshitij Srivastava, Anvesha Srivastava, Leon J. de Windt
PLoS ONE.2012; 7(11): e50966. CrossRef
miR-196a2 polymorphisms and susceptibility to cancer: A meta-analysis involving 24,697 subjects
PINGYU WANG, SHUYANG XIE, AIDONG CUI, YANXIANG ZHANG, BAOFA JIANG
Experimental and Therapeutic Medicine.2012; 3(2): 324. CrossRef
miR-196a2 C allele is a low-penetrant risk factor for cancer development
Li-Xin Qiu, You Wang, Zu-Guang Xia, Bo Xi, Chen Mao, Jia-Lei Wang, Bi-Yun Wang, Fang-Fang Lv, Xiang-Hua Wu, Ling-Qing Hu
Cytokine.2011; 56(3): 589. CrossRef

Frequency and Related Factors of Masked Hypertension at a Worksite in Korea: Sang-Kyu Kim, Jun-Ho Bae, Dung-Young Nah, Dong-Wook Lee, Tae-Yoon Hwang, Kyeong-Soo Lee; J Prev Med Public Health. 2011;44(3):131-139. Published online May 17, 2010; DOI: https://doi.org/10.3961/jpmph.2011.44.3.131

9,938 View
77 Download
5 Crossref

Abstract PDF

Objectives

Masked hypertension is associated with metabolic risks and increased risk of cardiovascular disease. The purpose of this study was to identify the frequency of and risk factors of masked hypertension in Korean workers.

Methods

The study was conducted among 121 employees at a hotel in Gyeongju, Korea, from December 2008 to February 2009. We measured blood pressure (BP) both in the clinic and using 24-hour ambulatory BP monitors for all subjects. Hypertension was defined independently by both methods, and subjects were classified into four groups: true normotension, masked hypertension, white coat hypertension, and sustained hypertension.

Results

The frequency of masked hypertension in our study group was 25.6%. Compared with true normotension, the factors related to masked hypertension were male gender (odds ratio [OR], 10.7; 95% confidence interval [CI], 1.41 to 81.09), aging one year (OR, 0.88; 95% CI, 0.78 to 0.99), clinic BP 120-129/80-84 mmHg (OR, 8.42; 95% CI, 1.51 to 46.82), clinic BP 130-139 / 85-89 mmHg (OR, 12.14; 95% CI, 1.80 to 81.85), smoking (OR, 5.51; 95% CI, 1.15 to 26.54), and increase of total cholesterol 1 mg / dL (OR, 1.05; 95% CI, 1.02 to 1.08). In males only, these factors were clinic BP 120-129 / 80-84 mmHg (OR, 15.07; 95% CI, 1.55 to 146.19), clinic BP 130-139 / 85-89 mmHg (OR, 17.16; 95% CI, 1.56 to 189.45), smoking (OR, 11.61; 95% CI, 1.52 to 88.62), and increase of total cholesterol 1 mg/dL (OR, 1.05; 95% CI, 1.01 to 1.09).

Conclusions

The frequency of masked hypertension was high in our study sample. Detection and management of masked hypertension, a known strong predictor of cardiovascular risk, could improve prognosis for at-risk populations.

Summary

Citations

Citations to this article as recorded by

Does This Adult Patient Have Hypertension?
Anthony J. Viera, Yuichiro Yano, Feng-Chang Lin, David L. Simel, Jonathan Yun, Gaurav Dave, Ann Von Holle, Laura A. Viera, Daichi Shimbo, Shakia T. Hardy, Katrina E. Donahue, Alan Hinderliter, Christiane E. Voisin, Daniel E. Jonas
JAMA.2021; 326(4): 339. CrossRef
Prevalence and determinants of masked hypertension among obese individuals at the Yaoundé Central Hospital: a cross-sectional study in sub-Saharan Africa
Bâ Hamadou, Sylvie Ndongo Amougou, Yolande Tchuendem, Chris Nadège Nganou-Gnindjio, Liliane Mfeukeu-Kuate, Audrey Joyce Foka, Aurel T. Tankeu, Ahmadou Musa Jingi, Alain Patrick Menanga, Samuel Kingue
Blood Pressure Monitoring.2020; 25(4): 212. CrossRef
Frequency of masked hypertension and its relation to target organ damage in the heart
Abdulsalam Mahmoud Algamal
The Egyptian Heart Journal.2016; 68(1): 53. CrossRef
Relationship between epistaxis and hypertension: A cause and effect or coincidence?
Nabil Abdulghany Sarhan, Abdulsalam Mahmoud Algamal
Journal of the Saudi Heart Association.2015; 27(2): 79. CrossRef
Blood pressure variability over 24 h: prognostic implications and treatment perspectives. An assessment using the smoothness index with telmisartan–amlodipine monotherapy and combination
Gianfranco Parati, Helmut Schumacher
Hypertension Research.2014; 37(3): 187. CrossRef

First
Prev
Page of 1
Next
Last

Previous issues