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Volume 53(1); January 2020
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Climate Change: Editorial
Climate Change and Health: More Research Is Still Needed
Ho-Jang Kwon
J Prev Med Public Health. 2020;53(1):1-2.   Published online January 31, 2020
DOI: https://doi.org/10.3961/jpmph.20.005
  • 3,864 View
  • 211 Download
  • 4 Crossref
AbstractSummary PDF
Summary
Korean summary
2018년에 경험한 최악의 폭염 사례에서도 볼 수 있듯이 기후변화로 인한 건강피해는 현실이 되고 있다. 의료인들은 기후변화에 적응할 수 있는 대책을 수립하는데 적극적으로 참여해야 하고 특히 기후변화 적응대책의 과학적 근거를 만드는데 기여해야 한다.

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  • A distributed lag non-linear time-series study of ambient temperature and healthcare-associated infections in Hefei, China
    Yile Wu, Mingming Liang, Qiwei Liang, Xiyao Yang, Yehuan Sun
    International Journal of Environmental Health Research.2023; 33(3): 258.     CrossRef
  • Green Lean Six Sigma sustainability – oriented project selection and implementation framework for manufacturing industry
    Mahender Singh Kaswan, Rajeev Rathi, Jose Arturo Garza-Reyes, Jiju Antony
    International Journal of Lean Six Sigma.2023; 14(1): 33.     CrossRef
  • Green Lean Six Sigma for sustainability improvement: a systematic review and future research agenda
    Vishwas Yadav, Mahender Singh Kaswan, Pardeep Gahlot, Raj Kumar Duhan, Jose Arturo Garza-Reyes, Rajeev Rathi, Rekha Chaudhary, Gunjan Yadav
    International Journal of Lean Six Sigma.2023; 14(4): 759.     CrossRef
  • Climate Change and the Need for Future Research
    Nasrat Adamo, Nadhir Al-Ansari, Varoujan Sissakian
    IOP Conference Series: Earth and Environmental Science.2022; 1120(1): 012029.     CrossRef
Climate Change: Review
Research Trends in Agenda-setting for Climate Change Adaptation Policy in the Public Health Sector in Korea
Su-Mi Chae, Daeeun Kim
J Prev Med Public Health. 2020;53(1):3-14.   Published online January 31, 2020
DOI: https://doi.org/10.3961/jpmph.19.326
  • 6,315 View
  • 179 Download
  • 2 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Many studies have been conducted to assess the health effects of climate change in Korea. However, there has been a lack of consideration regarding how the results of these studies can be applied to relevant policies. The current study aims to examine research trends at the agenda-setting stage and to review future ways in which health-related adaptation to climate change can be addressed within national public health policy. A systematic review of previous studies of the health effects of climate change in Korea was conducted. Many studies have evaluated the effect of ambient temperature on health. A large number of studies have examined the effects on deaths and cardio-cerebrovascular diseases, but a limitation of these studies is that it is difficult to apply their findings to climate change adaptation policy in the health sector. Many infectious disease studies were also identified, but these mainly focused on malaria. Regarding climate change-related factors other than ambient temperature, studies of the health effects of these factors (with the exception of air pollution) are limited. In Korea, it can be concluded that studies conducted as part of the agenda-setting stage are insufficient, both because studies on the health effects of climate change have not ventured beyond defining the problem and because health adaptation to climate change has not been set as an important agenda item. In the future, the sharing and development of relevant databases is necessary. In addition, the priority of agenda items should be determined as part of a government initiative.
Summary
Korean summary
이 연구는 한국에서 수행된 기후변화에 따른 건강영향 연구의 동향을 살펴봄으써, 기후변화 건강 적응이 보건 정책의 어젠다로 자리 잡기 위한 연구 방향을 검토했다. 향후 국가는 기후변화 적응을 위한 우선순위 건강 문제를 검토해야 하며, 관련된 연구의 양과 질을 확보해 국가 전략의 기초가 될 수 있도록 해야 한다.

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  • Heat impacts on human health in the Western Pacific Region: an umbrella review
    Y.T.Eunice Lo, Emily Vosper, Julian P.T. Higgins, Guy Howard
    The Lancet Regional Health - Western Pacific.2024; 42: 100952.     CrossRef
  • Climate Change and Health: More Research Is Still Needed
    Ho-Jang Kwon
    Journal of Preventive Medicine and Public Health.2020; 53(1): 1.     CrossRef
Climate Change: Original Article
Association Between Air Conditioning Use and Self-reported Symptoms During the 2018 Heat Wave in Korea
Yong-Han Lee, Sanghyuk Bae, Seung-sik Hwang, Jong-Hun Kim, Kyoung-Nam Kim, Youn-Hee Lim, Miji Kim, Sohwa Jung, Ho-Jang Kwon
J Prev Med Public Health. 2020;53(1):15-25.   Published online November 26, 2019
DOI: https://doi.org/10.3961/jpmph.19.171
  • 6,250 View
  • 220 Download
  • 2 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Objectives
The purpose of this study was to investigate the health effects of air conditioning use during the 2018 heat wave in Korea, included the highest temperature ever recorded in the nation.
Methods
The participants in this study were 1000 adults aged 19 years and older recruited from across Korea. The participants were asked about their experience of symptoms of various diseases, disruptions of their daily lives, and use of air conditioning during the heat wave. The associations between air conditioning use during the heat wave and health outcomes were analyzed using the chi-square test and multiple logistic regression models.
Results
Among participants who lacked air conditioning in the main space where they spent time outside the home, 33.9%, 8.1%, 43.5%, and 19.4% experienced symptoms of heat-related, cardiovascular, nervous system diseases, and air-conditioningitis, respectively. In comparison, participants who did have air conditioning outside the home experienced the same symptoms at proportions of 21.0%, 1.9%, 26.8%, and 34.2%, respectively (p=0.027, 0.007, 0.007, and 0.023, respectively). Among participants who had no air conditioner at home, 10.0% were absent from school or work due to the heat wave. In contrast, among participants who had an air conditioner at home, only 3.7% were absent as a result of the heat wave (p=0.007).
Conclusions
When air conditioning was not used at home or in the main space where participants spent time outside the home during the 2018 heat wave, adverse health effects were more prevalent, but the risk of air-conditioningitis was reduced.
Summary
Korean summary
본 연구는 한국 기상관측사상 가장 더웠던 2018년 한국의 폭염 기간 동안, 에어컨 사용이 건강에 미치는 영향에 대해 조사하였다. 가정 외 주 생활공간에 에어컨이 가동되지 않거나 가정에 에어컨이 없으면 폭염 기간 동안의 건강 및 일상생활에 좋지 않은 영향을 줄 수 있으나, 냉방병 위험은 낮아질 수 있다.

Citations

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  • Integration and Optimal Control of MicroCSP with Building HVAC Systems: Review and Future Directions
    Mohamed Toub, Chethan R. Reddy, Rush D. Robinett, Mahdi Shahbakhti
    Energies.2021; 14(3): 730.     CrossRef
  • Climate Change and Health: More Research Is Still Needed
    Ho-Jang Kwon
    Journal of Preventive Medicine and Public Health.2020; 53(1): 1.     CrossRef
Climate Change: Perspective
Characteristics of Heat Waves From a Disaster Perspective
Do-Woo Kim, Chaeyoung Kwon, Jineun Kim, Jong-Seol Lee
J Prev Med Public Health. 2020;53(1):26-28.   Published online January 31, 2020
DOI: https://doi.org/10.3961/jpmph.19.315
  • 3,900 View
  • 150 Download
  • 4 Crossref
AbstractAbstract AbstractSummary PDF
In September 2018, heat waves were declared to be a type of natural disaster by the Framework Act on the Management of Disasters and Safety. The present study examined the characteristics of heat waves from the perspectives of meteorological phenomena and health damage. The government’s efforts to minimize the damages incurred by heat waves are summarized chronologically. Furthermore, various issues pertaining to heat waves that are being raised in our society despite the government’s efforts are summarized by analyzing big data derived from reported news and academic articles.
Summary
Korean summary
2018년 9월, 폭염이 재난 및 안전 관리 기본법 상 자연재난의 한 유형으로 명시되었다. 본 연구는 다른 자연재난들과 구별되는 폭염 재난의 특징들을 기상학적과 보건학적 측면으로 나누어 제시하였다. 또한 폭염 피해를 줄이기 위한 그간 정부의 각종 노력들을 시간순서대로 정리하였으며, 뉴스와 논문 빅데이터 분석을 통해 최근에 우리사회에서 폭염과 관련된 어떤 이슈들이 떠오르고 있는지도 살펴보았다.

Citations

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  • The Evaluation of the Temperature Reduction Effects of Cool Roofs and Cool Pavements as Urban Heatwave Mitigation Strategies
    Sunmin Lee, Young-Il Cho, Moung-Jin Lee, Young-Shin Lim
    Applied Sciences.2023; 13(20): 11451.     CrossRef
  • Heatwaves in Southern Armenia in the context of climate change
    Hrachuhi Galstyan, Babak Shiri, Tatevik Safaryan
    International Journal of Climatology.2022; 42(6): 3431.     CrossRef
  • Health status of women affected by homelessness: A cluster of in concreto human rights violations and a time for action
    Maria G. Grammatikopoulou, Konstantinos Gkiouras, Aleks Pepa, Angeliki Persynaki, Eleftheria Taousani, Maria Milapidou, Emmanouil Smyrnakis, Dimitrios G. Goulis
    Maturitas.2021; 154: 31.     CrossRef
  • Climate Change and Health: More Research Is Still Needed
    Ho-Jang Kwon
    Journal of Preventive Medicine and Public Health.2020; 53(1): 1.     CrossRef
Original Articles
The Effect of Prenatal Cadmium Exposure on Attention-deficit/Hyperactivity Disorder in 6-Year-old Children in Korea
Woosung Kim, Yoonyoung Jang, Youn-Hee Lim, Bung-Nyun Kim, Choong Ho Shin, Young Ah Lee, Johanna Inhyang Kim, Yun-Chul Hong
J Prev Med Public Health. 2020;53(1):29-36.   Published online November 14, 2019
DOI: https://doi.org/10.3961/jpmph.19.175
  • 5,031 View
  • 170 Download
  • 10 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Objectives
Prenatal cadmium (Cd) exposure may be associated with attention-deficit/hyperactivity disorder (ADHD) in children. Therefore, the objective of this study was to examine the relationship between Cd exposure during gestation and ADHD at 6 years of age.
Methods
As part of an ongoing cohort study (the Environment and Development of Children study), 479 mother-child pairs from Seoul, Korea were included for analysis between 2008 and 2011. The whole blood concentration of Cd was analyzed using atomic absorption spectrophotometry. The parents were surveyed about ADHD behaviors in their children at age 6. Multivariable linear regression models were used to investigate the relationship between prenatal exposure to Cd and ADHD at 6 years of age.
Results
Increased prenatal Cd concentrations were associated with increased scores for ADHD for girls, but not for boys, at age 6. A 2-fold increase in the prenatal Cd level was significantly associated with a 22.3% (95% confidence interval, 11.6 to 34.1) increase in ADHD in girls at 6 years of age, as indicated by the linear regression model.
Conclusions
Our results identified significant associations between prenatal Cd exposure and ADHD scores in 6-year-old girls.
Summary
Korean summary
이 연구의 목적은 산모와 아이의 코호트 추적조사 상 임신 중 혈중의 중금속 카드뮴 농도가 6세 아이의 주의력결핍 과잉행동 장애(ADHD)와 연관이 있는지를 확인하는 것이다. 자료원으로는 환경부와 식약처 지원 어린이 코호트인 환경노출과 어린이 성장 코호트 (EDC)를 이용하였다. 총 479쌍의 산모-아이 쌍을 대상으로 다변수 선형 회귀분석을 통해 연관성을 살펴보았다. 연구 결과, 임신 중 산모의 혈중 카드뮴 농도가 2배 증가함에 따라 6세 여아의 한국어판 주의력결핍장애(ADHD) 평점척도 (K-ARS) 점수가 22.3% 증가하는 것으로 나타났다.

Citations

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  • Co-exposure to toxic metals and phthalates in pregnant women and their children’s mental health problems aged four years — Taiwan Maternal and Infant Cohort Study (TMICS)
    Tsung-Lin Tsai, Chia-Jung Hsieh, Ming-Tsang Wu, Mei-Lien Chen, Po-Hsiu Kuo, Shu-Li Wang
    Environment International.2023; 173: 107804.     CrossRef
  • Effects of cadmium on children and adolescents development (systematic review)
    Natalia D. Bobrisheva-Pushkina, Lubov Yu. Kuznetsova, Maksim Yu. Mozganov, Azaliya N. Araslanova, Aleksandra A. Kordina, Gennadij G. Onishchenko
    Hygiene and sanitation.2023; 102(9): 947.     CrossRef
  • Quality and risk assessment of lead and cadmium in drinking water for child development centres use in Phatthalung province, Thailand
    Somsiri Decharat, Piriyalux Phethuayluk
    Environmental Analysis Health and Toxicology.2023; 38(4): e2023020.     CrossRef
  • Developmental exposure to environmental levels of cadmium induces neurotoxicity and activates microglia in zebrafish larvae: From the perspectives of neurobehavior and neuroimaging
    Yanyi Xu, Haiyu Zhao, Zuo Wang, Hao Gao, Junru Liu, Kemin Li, Zan Song, Cong Yuan, Xianyong Lan, Chuanying Pan, Shengxiang Zhang
    Chemosphere.2022; 291: 132802.     CrossRef
  • The Association between ADHD and Environmental Chemicals—A Scoping Review
    Sonja Moore, Laura Paalanen, Lisa Melymuk, Andromachi Katsonouri, Marike Kolossa-Gehring, Hanna Tolonen
    International Journal of Environmental Research and Public Health.2022; 19(5): 2849.     CrossRef
  • Elemental composition of the hair and milk of black-spotted cows and its relationship with intestinal microbiome reorganization
    Elena Sizova, Elena Yausheva, Olga Marshinskaia, Tatiana Kazakova, Yuriy Khlopko, Svyatoslav Lebedev
    Veterinary World.2022; : 2565.     CrossRef
  • Associations Between Thyroid Hormone Levels and Urinary Concentrations of Bisphenol A, F, and S in 6-Year-old Children in Korea
    Yoonyoung Jang, Yoon-Jung Choi, Youn-Hee Lim, Kyung-Shin Lee, Bung-Nyun Kim, Choong Ho Shin, Young Ah Lee, Johanna Inhyang Kim, Yun-Chul Hong
    Journal of Preventive Medicine and Public Health.2021; 54(1): 37.     CrossRef
  • ADHD: Reviewing the Causes and Evaluating Solutions
    Luis Núñez-Jaramillo, Andrea Herrera-Solís, Wendy Verónica Herrera-Morales
    Journal of Personalized Medicine.2021; 11(3): 166.     CrossRef
  • Metal and essential element concentrations during pregnancy and associations with autism spectrum disorder and attention-deficit/hyperactivity disorder in children
    Thea S. Skogheim, Kjell Vegard F. Weyde, Stephanie M. Engel, Heidi Aase, Pål Surén, Merete G. Øie, Guido Biele, Ted Reichborn-Kjennerud, Ida H. Caspersen, Mady Hornig, Line S. Haug, Gro D. Villanger
    Environment International.2021; 152: 106468.     CrossRef
  • Effect of Cadmium on Children's Health in Prenatal and Postnatal Periods of Development
    S. S. Ostrovska, Yu. P. Myasoid, R. V. Kovtunenko, V. A. Myakushko, G. P. Chernenko, I. Y. Pismenetska, V. V. Baklunov
    Ukraïnsʹkij žurnal medicini, bìologìï ta sportu.2021; 6(5): 414.     CrossRef
Effects of Comorbid Sleep Disorders on Cardiovascular Complications of Hypertension Among Patients With Newly-diagnosed Hypertension: An Analysis of the Korean National Health Insurance Service-National Sample Cohort
Jeongmook Kang, Yoon-Hyung Park, Kwang Ik Yang, Jose Rene Bagani Cruz, Young Hwangbo
J Prev Med Public Health. 2020;53(1):37-44.   Published online November 6, 2019
DOI: https://doi.org/10.3961/jpmph.19.248
  • 8,842 View
  • 146 Download
  • 1 Crossref
AbstractAbstract AbstractSummary PDF
Objectives
This study investigated the effects of comorbid sleep disorders (SD) on the incidence of cardiovascular complications among newly-diagnosed hypertension (HTN) patients.
Methods
As study population, 124 057 newly-diagnosed essential HTN patients aged 30 or older, without cardiovascular complications at diagnosis with HTN, were selected from the National Health Insurance Service-National Sample Cohort. The incidence of cardiovascular complications was calculated, Cox proportional-hazards regression model was used to analyze the risk of complications, and the population attributable fraction (PAF) for cardiovascular complications of having comorbid SD at HTN diagnosis was calculated.
Results
Over 10 years, 32 275 patients (26.0%) developed cardiovascular complications. In HTN patients with comorbid SD at diagnosis of HTN, the incidence of cardiovascular complications (78.3/1000 person-years; 95% confidence interval [CI], 75.8 to 80.9) was higher than in those without comorbid SD (58.6/1000 person-years; 95% CI, 57.9 to 59.3) and the risk of cardiovascular complications was 1.21 times higher (95% CI, 1.17 to 1.25), adjusting for age, gender, income, area of residence, and comorbid diabetes mellitus. The PAF of having comorbid SD at diagnosis of HTN for the incidence of cardiovascular complications was 2.07% (95% CI, 1.69 to 2.44).
Conclusions
Newly-diagnosed essential HTN patients aged 30 or older who had comorbid SD at the time of their HTN diagnosis had a higher incidence of cardiovascular complications than those without comorbid SD. Age, gender, income, area of residence, and comorbid diabetes mellitus had a significant effect on the incidence of cardiovascular complications. Approximately 2% of cardiovascular complications were found to occur due to the presence of SD.
Summary
Korean summary
본 연구 결과 심뇌혈관 합병증이 없었던 30세 이상 신규 일차성 고혈압 환자에서 고혈압 진단시 수면장애을 동반한 경우 심뇌혈관합병증 발생율은 78.3/1000인년(95% CI 75.8-80.9)으로 나타났으며, 수면장애을 동반하지 않은 경우 심뇌혈관합병증 발생율은 58.6/1000인년(95%CI 57.9-59.3)인 것으로 관찰되었다. 고혈압 진단시의 연령, 성별, 수입, 거주지역, 동반된 당뇨병력을 보정한 다중회귀분석에서 수면장애병력이 있는 고혈압 환자군의 심뇌혈관합병증 발생 위험도는 수면장애병력이 없는 환자에 비하여 1.21배(95% CI 1.17-1.25) 높은 것으로 나타났으며, 연구대상자에게 발생한 심뇌혈관합병증의 약 2%는 고혈압 진단시 동반된 수면장애가 기여한 것으로 분석되었다.

Citations

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  • Association Between Sleep Quality and Anxiety in Korean Adolescents
    Hyunkyu Kim, Seung Hoon Kim, Sung-In Jang, Eun-Cheol Park
    Journal of Preventive Medicine and Public Health.2022; 55(2): 173.     CrossRef
Comparison of Trends in Blood Pressure and the Prevalence of Obesity Among Korean and American Adolescents: A 12-Years Cross-sectional Study
Somi Heo, Seyoung Kwon, Yu-Mi Lee, Ji-Yeon Shin, Duk-Hee Lee
J Prev Med Public Health. 2020;53(1):45-55.   Published online November 20, 2019
DOI: https://doi.org/10.3961/jpmph.19.198
  • 4,660 View
  • 196 Download
  • 7 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Objectives
This study was conducted to explore recent trends in the prevalence of pediatric elevated blood pressure and hypertension (HTN) in Korea and the United States, applying the new HTN reference values for adolescents.
Methods
This study analyzed 17 339 (8755 Korean and 8584 American) adolescents aged 10 to 17 who participated in the Korea National Health and Nutrition Examination Survey and the National Health and Nutrition Examination Survey, respectively, between 2005 and 2016. HTN was defined using percentile-based reference values for non-overweight adolescents from 7 nations, and obesity was defined by body mass index (BMI) based on country-specific growth charts. All analyses were stratified by sex and year-over-year changes were evaluated by calculating the p for trend.
Results
Systolic blood pressure showed a statistically meaningful upward trend in Korean boys and girls, while diastolic blood pressure did not show any significant changes. Both systolic and diastolic blood pressure levels declined among United States boys and girls. The prevalence of elevated blood pressure and HTN remained similar in Korean adolescents, but declined in both sexes among United States adolescents. BMI increased in both sexes among Korean adolescents, although the overweight and obesity rates stayed the same. No significant trends were found in any obesity indices among United States adolescents. The prevalence of elevated blood pressure and HTN by obesity level was higher among Korean adolescents than among their United States peers in both sexes, and the gap became higher at more severe levels of obesity.
Conclusions
Despite the strong correlation between obesity and HTN, recent trends in the prevalence of HTN and obesity among Korean and United States adolescents were strikingly different. Follow-up studies are necessary to determine why the prevalence of HTN was more than twice as high among Korean adolescents than among their United States counterparts.
Summary
Korean summary
본 연구에서는 새로운 소아청소년 고혈압 기준을 이용하여, 최근 한국과 미국 소아청소년들의 혈압 및 고혈압 유병률의 변화 추이를 비교하였다. 비만과 고혈압간의 높은 관련성에도 불구하고 한국과 미국 소아청소년의 고혈압 유병률과 비만율은 서로 다른 변화 추이를 나타내었으며, 고혈압 발생에 있어서 한국 소아청소년들이 미국 소아청소년들보다 비만에 더 취약할 가능성을 나타내고 있어 이에 관한 후속연구가 필요하다.

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    Melike TELLİOĞLU, Muammer YILMAZ, İnci ARIKAN, Yaşar ÇAKMAKÇI
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    Sangjun Lee, Jieun Jang, Sarah Krull Abe, Shafiur Rahman, Eiko Saito, Rashedul Islam, Prakash C Gupta, Norie Sawada, Akiko Tamakoshi, Xiao-Ou Shu, Woon-Puay Koh, Atsuko Sadakane, Ichiro Tsuji, Jeongseon Kim, Isao Oze, Chisato Nagata, San-Lin You, Myung-He
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    Brittany N. Morey, Connie Valencia, Sunmin Lee
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Association Between Atrial Fibrillation and the Risk of Dementia in the Korean Elderly: A 10-Year Nationwide Cohort Study
Min-Ah Nah, Kyeong Soo Lee, Tae-Yoon Hwang
J Prev Med Public Health. 2020;53(1):56-63.   Published online January 3, 2020
DOI: https://doi.org/10.3961/jpmph.19.117
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AbstractAbstract AbstractSummary PDF
Objectives
The objective of this study was to determine the effect of atrial fibrillation (AF) on the risk of dementia in the Korean elderly.
Methods
A 10-year retrospective cohort study was conducted using the National Health Insurance Service-Senior Cohort database. We excluded those who were under 65 years of age as of January 2006 (n=46 113), those who were diagnosed with dementia between 2002 and 2005 (n=9086), and those with a history of stroke prior to AF diagnosis (n=8392). We used a Cox proportional hazards model with a time-varying covariate to determine whether AF is associated with the risk of dementia after adjusting for potential confounders.
Results
In univariable Cox regression, the hazard ratio (HR) of dementia according to AF status was 1.28 (95% confidence interval [CI], 1.23 to 1.33). After adjusting for potential confounders, AF was found to increase the risk of dementia (HR, 1.12; 95% CI, 1.07 to 1.17), Alzheimer dementia (HR, 1.12; 95% CI, 1.07 to 1.17), and vascular dementia (HR, 1.10; 95% CI, 1.03 to 1.18). In patients diagnosed with AF, the incidence of dementia was lower (HR, 0.50; 95% CI, 0.47 to 0.52) in patients who were treated with oral anticoagulants.
Conclusions
Investigating the potential risk factors of dementia in an aged society is important. We found a slightly higher risk of dementia in those with AF than in those without AF, and we therefore concluded that AF is a potential risk factor for dementia.
Summary
Korean summary
본 연구에서는 국민건강보험공단 노인표본코호트 자료를 사용하여 심방세동의 유무가 치매의 발생위험과 연관되어 있는지 분석하였다. 잠재적인 교란변수들을 통제하여 분석한 결과 심방세동은 치매(HR 1.12, 95% CI 1.07 to 1.17), 알츠하이머 치매(HR 1.12, 95% CI 1.07 to 1.17), 혈관성 치매(HR 1.10, 95% CI 1.03 to 1.18) 발생과 연관되어 있는 것으로 나타났다. 한 편, 심방세동 환자에서의 항응고제 복용은 치매 발생위험(HR 0.50, 95% CI 0.47 to 0.52)을 감소시키는 것으로 나타났다.

Citations

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