- Nitric Oxide-Mediated Cytotoxicity of Manganese in Basal Ganglia Neuronal Cells.
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Dong Hoon Shin, Yong Wook Jung, Jae Hoon Bae, Dae Kyu Song, Won Kyun Park, Bok Hyun Ko, Doo Hie Kim
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Korean J Prev Med. 1999;32(4):459-466.
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- OBJECTIVES
We have investigated to manifest whether manganese-induced neurotoxicity is mediated by nitric oxide(NO) in the rat primary neuronal cultures and assess the effect of Mn2+ on the N-methyl-D aspartate(NMDA) receptors. METHODS: We have used 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT)assay to examine the effect of cytotoxicity of MnCl2 in neuronal cells . NO production was determined by measuring nirites, a stable oxidation product of NO. The neurons in the rat that contains neuronal nitric oxide synthase(nNOS) were examined by immunofluorescence and confocal microscopy. The effects of Mn2+ on the NMDA receptors was assesed by the whole cell voltage clamp technique. RESULTS: We showed that the NO release and NOS expression were increased with 500uM MnCl2 treatment and an NOS inhibitors, NG-nitro-L-arginine , prevented neurotoxicity elicited by manganese. In the electrophysiological study, Mn2+ does not block or activate the NMDA receptors and not pass through the NMDA receptors in a neurons of basal ganglia. CONCLUSIONS: It is concluded that manganese neurotoxicity in basal ganglia was partially mediated by nitric oxide in the cell culture model.
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Summary
- A Case Report on the Meniscal Tear due to Repetitive Foot-Switch Stepping.
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Sun Hee Yu, Hyun Sul Lim, Doo Hie Kim, Dong Ju Chae, Suk Kang
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Korean J Prev Med. 1997;30(4):805-814.
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- Injuries to the menisci occur in a variety of ways, most commonly with a twist, pivot, squat, or valgus stress to the knee. Tear patterns are classified to longitudinal, horizontal, or transverse features according to the mechanism of injury. Work-related meniscal tear usually occurs with a repetitive usage of the foot, hence it can be classified as a cumulative traumatic disorder. We found a 47 year-old female worker who had been taking charge of repetitive foot-switch stepping for 8 years. She suffered from pain in the right knee since 5 months ago. Tenderness along the medial joint line of the right knee was observed and pain was aggravated with full flexion of the right knee. On magnetic resonance imaging, high signal intensity was observed at the posterior horn of the medial meniscus of the right knee. Degenerative longitudinal and transverse complex tear in the medial meniscus was observed on arthroscopy. Arthroscopic partial meniscectomy was performed. We surveyed the work process and the health status of co-workers. It turned out that the work process was compatible to injure the meniscus and nine out of fourteen co-workers(64.3%) complained pain of the knee. No other factors related to her meniscal tear could be found except for the situation at her work. Therefore, we conclude that meniscal tear is related to the repetitive stepping of foot switch.
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Summary
- Respiratory symptoms of workers exposed to the fume containing manganese.
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Sun Hee Yu, Doo Hie Kim, Hyun Sul Lim, Ji Yong Kim, Byung Soon Choi
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Korean J Prev Med. 1997;30(4):752-763.
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- To evaluate the effect of manganese on the respiratory system, we investigated the respiratory symptoms of 63 male workers exposed to fume containing manganese (Mn), iron (Fe), and silica (Si), and compared them with those of 66 male workers not exposed to the fume in a manganese alloy smelting factory. The prevalence ratios of the seven respiratory symptoms were not different between two groups. The presence of any respiratory symptom was not related with the age, duration of employment, smoking status of workers, and exposure to fume. In furnace workers, it was not related with the airborne Mn, Fe, and Si concentration in the total or respirable fume. Airborne Mn concentrations of all 4 furnaces in the respirable fume were below 1 mg/m(3). There were two suspicious cases of pneumoconiosis among furnace workers and one definite case(1/2) among casting workers who were not exposed to fume. The above results suggest that the exposure to the low airborne Mn concentration is not related with respiratory symptoms and pneumoconiosis. However, it is necessary to study the respiratory effects of Mn using the symptom questionnaire with consideration of the severity and persistence of symptoms and the time interval from exposure.
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Summary
- Phototoxic Dermatosis among Coal-tar Pitch Workers.
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Cheol Jung, Hyun Sul Lim, Doo Hie Kim, Yeol Oh Sung
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Korean J Prev Med. 1997;30(1):145-156.
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- Interview survey and dermatological examination have been performed to investigate the health problems of workers continuously exposed to coal-tar pitch. The phototoxicity of coal-tar pitch was confirmed by the photopatch tests for six healthy adults. The main results are followings; 1. There was no special history of allergic diseases in both the exposed and non-exposed group. 2. The frequency of the phototoxic dermatosis and the coal-tar acne in the exposed group was significantly greater(p<0.05) than that of the control group. In the exposed group, the phototoxic dermatosis and the coal-tar acne were observed in nine workers(90%) and seven workers(70%), respectively. However, those disease were not observed in the control group. 3. Five results(83%) were positive to the photopatch test for coal-tar pitch 48 hours after UVA irradiation. But the lesion was subsiding 72 hours after UVA irradiation. 4. Malignant cancers were not reported among workers ever exposed to coal-tar pitch. In conclusion, it appears that workers exposed to coal-tar pitch have high risks of phototoxic dermatosis and coal-tar acne. A health policy should be provided to prevent phototoxic dermatosis among coal-tar pitch workers. More studies are required to determine malignancy.
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Summary
- Neurobehavioral Changes according to Cumulative Exposure of Complex Organic Solvents.
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Duk Hee Lee, In Geun Park, Jin Ha Kim, Young Hawn Lee, Sung Gye Kang, Doo Hie Kim
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Korean J Prev Med. 1995;28(2):386-397.
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- A cross sectional study was performed to evaluate the neurobehavioral effects of chronic exposure of complex organic solvents, using NCTB(Neurobehavioral Core Test Battery) recommended by WHO(World Health organization). Forty female shoe factory workers and twenty-two controls matched with age were participated. The tests were performed in the morning before start of work, to exclude the effects of acute exposure. Workers were exposed mainly to toluene, methyl ethyl ketone, n-hexane, cyclo-hexane, dichloroethylene, trichloroethylene, benzene, xylenes etc. The ranges of present solvent exposure of hygienic effect were 0.46~0.71 in the process using adhesives indirectly, and 1.83-2.39 in the process using it directly. We reclassified the subjects, according to cumulative exposure. It showed significantly poorer performances in high exposed group on Santa Ana Dexterity and Benton visual Retention, compared with control group. After controlling confounder, the significances were still remained. But, further cohort studies, having the information of personal exposure dose from entering a factory, are required to clarify the effects of chronic exposure of complex organic solvents in relation to dose and duration of exposure.
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Summary
- Prevalence of Preipheral arterial diseases(PAD) used by edinburgh claudication questionnaire among the elderly people in rural communities.
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Ji Yeon Son, Gui Yeon Kim, Jong Young Lee, Doo Hie Kim
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Korean J Prev Med. 1995;28(2):364-372.
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- Peripheral arterial disease(PAD) is a major health problem in the elderly population, so prevalence of PAD is investigated using Edinburgh claudication questionnaire. Subjects were over 65 years old in the kyeongsan county. The prevalence of PAD was 9.0% in total population(8.5% in men, 9.3% in women). definite claudication was 3.9%, atypical claudication was 5.l%. and, grade 1 was 4.4%, grade 2 was 4.6%. The prevalence of PAD was increased with age but not statistically significant. There was no difference of PAD by gender and smoking. PAD was significantly associated with systolic blood pressure positively. But, unexpectedly, PAD was significantly associated with BMl negatively. PAD are important elderly health problem in the our country. so the etiology and preventive methods of PAD will be researched on our country population.
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Summary
- Pilot Study for the Assessment of Physical Fitness among Male Workers in a TV Component Manufacturing Factory.
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Gwang Seo Choi, Young Ha Lee, Sung Hie Kim, Kuck Hyeun Woo, Gu Wung Han, Doo Hie Kim
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Korean J Prev Med. 1994;27(3):531-546.
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- In a TV component manufacturing factory, 102 male workers aged 20~39 years old were participated in testing for physical fitness. At the same time, worker's periodic health examination was done. Test battery for physical fitness include grip strength, trunk flexing, standing long jump, side step, single leg balance with eye close, push ups and Harvard step test. As a result of testing for physical fitness, synthetically, there is no difference between manufacturing workers and officers. By bioelectrical impedance test, it means a declining tendency to all 7 factors in the obese workers, and so, it is important for obese workers not only to promote physical fitness but also to promote health. Excluding grip strength and single leg balance with eye close, 5 fitness factors are negatively associated with degree of diastolic Blood pressure, but it is statistically not significant. And levels of SGOT & SGPT have no association with physical fitness factors.
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Summary
- Mercury Contents of Scalp Hair by Consumption Pattern of Fishes, Shellfishes and its Products.
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Won Shik Lee, Doo Hie Kim
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Korean J Prev Med. 1994;27(1):44-58.
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- This study was conducted to examine the levels of total and organic mercury in the scalp hair of the elementary school children and adults, and their relalionship with the consumption pattern of fishes and shellfishes. The scalp hair samples were collected from the occipital part of 115 children and 131 adults in costal, urban and rural areas of kyungpook province from June to August 1991. The mercury content was analysed by the atomic absorption spectrophotometer (model IL. 555)with atomic vapor accessory (model IL. 440). The total and organic mercury contents of hair were significantly higher (P<0.01) among the children who prefer fish and/or shellfish (7.728ppm, 6.610ppm), and canned fish and/or fish pastes (6.969 ppm, 5.885ppm) than those who prefer meat(4.822ppm, 3.905ppm) and vegetables(3.974ppm, 3.224 ppm). The children who prefer to eat the canned fish without cooking showed a higher mercury content than the children who prefer to eat it as stew or mixed with vegetables (P<0.01l). There was a dose-response relationship between the intake frequency of canned fish, raw fish and cooked fish and the content of total and organic mercury of hair; the children who eat fish almost everyday showed 2 times higher than those who eat rarely (P<0.0l). The mercury content in the hair of the children who eat raw fish was significantly higher than that of the children who eat boiled or broiled fish (P<0.01). The total and organic mercury contents of adult scalp hair increased with age up to the forties and slightly decreased in the fifties. The mercury contents of those who were engaged in the fishery and raw fish restaurant were 2 times higher than those of the farmers. The mercury content of the persons who were favorite dishes of fish and shellfish were most high, and who prefer raw fish were 2 times higher than those of the persons who prefer vegetables and broiled fish. The contents of total and organic mercury in adult scalp hair showed also a increasing tendency with the intake frequency of raw and cooked fish.
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Summary
- Relationship between Violent Criminal Behavior and Imbalance of Scalp Hair Minerals in Man.
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Doo Hie Kim, Bon Ki Jang, Duk Hee Lee, Sung Chul Hong, Byung Hie Kim
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Korean J Prev Med. 1994;27(1):25-43.
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- To estimate the factors to the inclination of the criminal violence, the content of trace minerals and toxic metals in the scalp hair were measured during the period from May 1992 to october 1992. One hundred eleven violent and 89 nonviolent criminal inmates of Taegu correctional Institute were selected. The inmates of violent criminals were imprisoned by murder, robber, rape, injury and violent acts. Those of nonviolent criminals were swindle, larceny, and adultery and had no history of institutional violence. The contents of two toxic metals(cadmium, lead) and five trace minerals(Cu, Fe, Zn, Mg, Na) were determined by an atomic absorption spectrophotometer(lL. 551). The contents of cadmium and lead in hair of violent criminals were significantly higher as 0.56+/-0.14ppm, 11.53+/-3.32ppm, respectively, than 0.42+/-0.20ppm, 9.63+/-4.31ppm of nonviolent group (P<0.01). But the level of copper was significantly lower than nonviolent group (P<0.05). The factors that had a significant correlation with the inclination of violence in multiple logistic regression analysis were cadmium (odds ratio=98.09), unmarried (odds ratio=0.39), many times of criminal history (odds ratio=l.57) and residence of rural area (odds ratio=0.44). The results suggest that the sub-toxic contents of cadmium and lead in the hair may be of potential effect on behavior, and the mineral analysis may be an important adjunctive diagnostic procedure. Further studies into this problem are necessary.
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Summary
- Factors related to poor school performance of elementary school children.
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Jung Han Park, Gui Yeon Kim, Kyu Sook Her, Ju Young Lee, Doo Hie Kim
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Korean J Prev Med. 1993;26(4):628-649.
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- This study was conducted to investigate the factors related to the poor school performance of the elementary school children. Two schools in Taegu, one in the affluent area and the other in the poor area, were selected and a total of 175 children whose school performance was within low 10 percentile(poor performers) and 97 children whose school performance were within high 5 percentile(good performers) in each class of 2nd, 4th and 6th grades were tested for the physical health, behavioral problem and family background. Each child had gone through a battery of tests including visual and hearing acuity, anthropometry(body weight, height, head circumference), intelligence(Kodae Stanford-Binet test), test anxiety(TAI-K), neurologic examination by a developmental pediatrician and heavy metal content(Pb, Cd, Zn) in hair by atomic absorption spectrophotometry. A questionnaire was administered to the mothers for prenatal and perinatal courses of the child, family environment, child's developmental history, and child's behavioral and learning problems. Another questionnaire was administered to the teachers of the children for the child's family background, arithmatic and language abilities and behavioral problem. The poor school performance had a significant correlation with male gender, high birth order, broken home, low educational and occupational levels of parents, visual problem, high test anxiety score, attention deficit hyperactivity disorder(ADHD), poor physical growth(weight, height, head circumference) and low I.Q. score. The factors that had a significant correlation with the poor school performance in multiple logistic regression analysis were child's birth order(odds ratio=2.06), male gender(odds ratio=5.91), broken home(odds ratio=9.29), test anxiety score(odds ratio=1.07), ADHD(odds ratio=9.67), I.Q. score(odds ratio=0.85) and height less than Korean standard mean-1 S. D.(odds ratio=11.12). The heavy metal contents in hair did not show any significant correlation with poor school performance. However the lead and cadmium contents were high in males than in females. The lead content was negatively correlated with child's grade(p<0.05) and zinc was positively correlated with grade(p<0.05). Among the factors that showed a significant correlation with the poor school performance, high birth order, short stature and ADHD may be modified by a good family planning, good feeding practice for infant and child, and early detection and treatment of ADHD. Also, teacher and parents should restrain themselves from inducing excessive test anxiety by forcing the child to study and over-expecting beyond the child's intellectual capability.
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Summary
- Assessment of the Naktong river pollution after phenol spillage from the Kumi industrial estates II, Korea.
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Doo Hie Kim, Bong Ki Jang, Sung Chul Hong, Hyo Jung Moon, Duck Hee Lee, Hae Ju Oh
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Korean J Prev Med. 1993;26(2):268-281.
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- The aquatic quality of the Naktong river after two of three months in June, 1991 with phenol spillage from a electrical factory in Kumi was investigated. The samples were collected at six sites of the Naktong river basin and Kachang and Kongsan lakes. Phenol was not detected from all water samples. Turbidity was very much increased to the down stream in the Naktong river. The BOD and COD values exceeded the 2nd grade(3 mg/l) of the Korean standard quality of Environmental Water Act at the all sampling sites of the Naktong river. Especially, the value of COD at Kaejin (12.5 mg/l) was poorly classified as to the 5th grade of water class for the environmental quality standards. Organophosphorous pesticides such as parathion, malathion, fenitrothion and diazinon were investigated but not detected. Diazinon was only detected at the Ilson bridge(1.42 ppb), Okkye stream(6.95 ppb), Waekwan bridge(0.32 ppb), Gangjung reservior(0.13 ppb), Kaejin(0.05 ppb). Of the carbamates such as carbanyl, isoprocarb and cabofuran, the carbofuran was detected all sites except tap water, and Kachang and Kongsan lakes. The content of heavy metals such ans Cd, Pb, Zn, Fe, Mn, Hg were not exceeding for drinking water standards at the all sampling region, but only mecury was detected from Okkye stream(0.018ppb) and Kaejin(0.09ppb). In the regions of Kachang and Kongsan lakes, the content of heavy metals were lower than that of reservoir of Naktong river.
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Summary
- Illness Associated With Contamination Of Drinking Water Supplies With Phenol.
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Doo Hie Kim, Sung Kook Lee, Byung Yeol Chun, Duk Hee Lee, Sung Chul Hong, Bong Ki Jang
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Korean J Prev Med. 1993;26(2):202-209.
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- A accidental spills of phenol(100%) to the river Nakdong with subsequent contamination of the tap water for about two million consumers in Taegu city of Korea were occurred in March 1991. A historical cohort study of 6,913 individuals was undertaken to determine the associated with illness. Population subjects were divided into two groups of exposed and unexposed. Exposed subjects were reported to be phenol associated symptoms significantly higher than those in a nearby unexposed area(39.6% vs 9.4%, p<0.01). Especially, in the related symptoms, highly significant differences were noted in the number of subjects reporting gastrointestinal illness such as nausea, vomiting, diarrhea, or abdominal pain. During the accident, study subjects who experienced peculiar taste or odor in the tap water were significantly higher in the exposed areas(92% vs 34.3%). Chlorophenols formed from chlorination of water may have aggravated the problem.
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Summary
- Some hair mineral contents of non-violent criminal and normal control.
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Sung Cheul Hong, Doo Hie Kim
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Korean J Prev Med. 1993;26(1):110-125.
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- This study was designed to determine whether non-violent criminal and normal control on the basis of concentration of levels of trace mineral and toxic metal by analysis of human scalp hair. The subjects were selected 87 nonviolent criminal from a prison population and 120 normal control from periodic health checks for study. Hair samples were taken from the napes and Minnesota Multiple Personality Inventory(MMPI) was performed also. Five trace mineral(Zn, Cu, Mg, Fe, Na) and two toxic metal(lead, cadmium) contents were determined by an atomic absorption spectrometer. The contents of zinc and magnesium in hair of non-violent criminal were significantly lower than the control group(p<0.01). In the case of lead and cadmium, mean value of criminal group was significantly higher than control group. Significantly higher T-score of MMPI was seen in non-violent criminal group for psychopathic deviate (Pd), paranoia scale(Pa), and Mania scale(Ma) than control group, but T-score of depression scale(D) was significantly higher in the control group. In the non-violent criminal group, the content of copper inversely proportion to T-score of Hs, D, Hy, Pd, Mf, Pa, Pt, Sc, Si except Ma, also Zinc inversely proportion to T-score of Hy, Mf, Pa, Pt. These results suggest that difference of some hair mineral contents exist between criminal and normal control group. Thus further studies are necessary to determine whether violent and nonviolent criminal group attributed biochemical imbalance with carefully constructed and controlled studies.
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Summary
- Relationship of Low Blood Cadmium and Zinc to Blood Pressure.
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Duk Hee Lee, Doo Hie Kim
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Korean J Prev Med. 1992;25(2):148-156.
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- A case-control study was conducted to investigate the relationship between blood cadmium, blood zinc and cadmium/zinc ratio and hypertension. Eighty-three hypertensive and seventy-seven normotensive study subjects matched for age and sex were selected from the workers who had no history of job-related cadmium exposure, in Ulsan city and it's vincinity, Korea. The blood cadmium in hypertensive group was 2.90 etag/mL, which was significantly higher than that of control group, 1.99 etag/mL(P<0.01). After stratifing for smoking and age variables, the relationship was still remained. The blood cadmium/zinc ratio in hypertensive group was 2.46, which was significantly higher than that of control group, 1.65(P<0.01). After stratifing for smoking and age variables, the relationship was still remained. There was no significant difference in blood zinc between hypertensive and control group. On multiple logistic regression analysis, the blood cadmium/zinc ratio is highly significant than blood cadmium. In conclusion, there is the possible relationship between blood cadmium level which has been known to be within normal limits and hypertension. But, further cohort studies to define the effect of cadmium on human hypertension are required.
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Summary
- The Relationship of Low-Level Blood Lead to Plasma Renin Activity and Blood Pressure.
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Soon Woo Park, Doo Hie Kim
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Korean J Prev Med. 1991;24(4):516-530.
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- A case-control study was conducted to investigate the effect of low-level blood lead on the blood pressure. The plasma renin activity (PRA) was measured also to investigate one of the possible mechanisms by which lead may play a role to influence on the blood pressure. Seventy-two hypertensive and sixty-nine control study subjects were selected from the workers who had no history of job-related lead exposure, in Ulsan city and it's vicinity, Korea. In addition to measuring blood lead levels and PRA, body mass index(BMI), hematocrit, serum sodium, potassium, creatinine, ionized calcium, and cholesterol were measured. Also, the habits of smoking, alcohol drinking and family history of hypertension were checked. The blood lead level of the hypertensive group was 19.8+/-5.5 microgram/dl, which was significantly higher than that of the control group, 12.5+/-4.7 microgram/dl (p<0.01). On multiple logistic regression analysis, the odds ratio of blood lead level on the occurrence of high blood pressure was 1.38, also statistically significant (p<0.01). There was no significant differences between the hypertensive and the control group in the PRA or In(PRA), but there was a marginally significant linear relationship between blood lead and PRA in the hypertensive group (p<0.1). In conclusion, blood lead level which has been known to be within normal limits may be one of the possible risk factors of hypertension and PRA alteration by lead may act as one of the mechanisms.
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Summary
- A Sanitary Survey on the Medicinal Water Springs Located near Taegu City (1986).
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Sang Duk Cha, Bong Ki Chang, Byung Yeol Chun, Doo Hie Kim
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Korean J Prev Med. 1986;19(2):273-280.
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- 'Medicinal water' have been used for the treatment of disease and the promotion of health. To study the quality and health effect of 'medicinal water', the eleven springs located near Taegu City during the period of March 27-February 17, 1986 were tested for biological and physiochemical examination and were checked for sanitary environment around the spring. Among them three springs (27.3%) had a good sanitary equipments and only one was negative for biological examination. Three 'medicinal water' were accepted as potable by physicochemical examination. According to above findings, all of the 'medicinal water' sampled from the springs located near Taegu City were not potable by this sanitary survey adopted Drinking Water Standard in Korea. Kachang and Youngchum 'medicinal water' were more contaminated by heavy metals and bacteria than those of other springs. To solve the problem of contamination by heavy metals that originated from uncertain sources, we should search for the sources of water contamination, remove it completely and also support the environmental equipments and management system in protection of safe 'medicinal water' supply.
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Summary
- Total Phenol Value in Urine for the Phenol Resin Workers.
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Kyu Dong Ahn, Doo Hie Kim
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Korean J Prev Med. 1986;19(2):224-232.
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- This study was conducted to evaluate health consequences of phenol resin workers for 6 weeks from February 21, to March 28, 1986. The subject population was 26 in a factory with phenol resin and control group was 30 non-exposed workers who were working in the other factory. The biological parameters chosen for this study were phenol concentration in working room-air, total phenol level in urine and BUN of phenol resin workers. The phenol concentration in working room-air and total phenol in urine were significantly correlated (r=0.791, p<0.01). The frequency of symptom and sign in phenol resin workers were higher than control group. The frequent symptom and sign were coughing, weight loss, poor appetite, headache, dyspnea, eye irritation and tinnitus, in order. Total phenol in urine was not reversed to normal range in spite of interruption of exposure for 4 days. The BUN value in blood and total phenol in urine were not correlated.
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Summary
- A Comparison of Gases and Heavy Metals in Blood between Urban and Rural Teenager.
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Sang Sook Lee, Doo Hie Kim
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Korean J Prev Med. 1985;18(1):129-136.
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- This paper is carried out to determine the venous blood gas components and heavy metals, such as lead, cadmium and copper, in blood between urban and rural teenager. The subjects were 34 in urban, Taegu city and 37 in rural, Euisung-Gun. But smokers were excluded. The specimens were sampled in May, 1985. The heavy metals were analyzed by atomic absorption spectrophotometry (IL. 551) and carboxy-Hb, Met-Hb, Hb, O2 and CO2, blood gas analyzer (IL. 1301) and CO-oximeter (IL. 282). In urban group, PO2 and O2-Hb were significantly lower than in rural (p<0.01, p<0.03, respectively), and HCO3 and TCO2 were significantly higher than in rural (p<0.01, p<0.01, respectively). CO-Hb concentration was rather higher in the rural group than the urban (p<0.03), other Met-Hb was higher in urban group than in the rural (p<0.01). Lead and cadmium were also significantly higher in the urban group (p<0.03, p<0.02, respectively).
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Summary
- Comparison of Respiratory Symptom between Urban and Rural Residents.
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Jung Suk Yoon, Doo Hie Kim
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Korean J Prev Med. 1985;18(1):113-128.
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- This paper was carried out for comparison of respiratory symptoms between urban and rural residents that is somewhat related to air pollution. And as urban residents, 470 persons of Daegu (Taegu) and 364 of Pohang were selected and 472 rural residents were also, in Eus ng-Gun, those who were responded to questionnaire distributed from April 10, 1984 to April 30 through students of middle or high school. The subjects were families of the student. The questionnaire was appropriately modified the item B of Cornell Medical Index by author. Looking into the rate of complaints about each part, generally, the rate in urban is higher than that in rural. Particularly it is higher to 'feeling a choking lump or swelling of throat', 'the sputum' and 'the asthma' in the city (p<0.05). On the contrary, women in the farm village, to 'caught a severe cold' as compared with the city. In men under nineteen years of age, it is higher than the farm village to 'feeling a choking lump or swelling of throat' of Pohang (p<0.05). But in men forties, it is higher than the city that farm people are 'soaking sweat at night' and 'foreign body sensation on throat'. Students hardly differ between the two ares, while the group having occupation in Pohang felt more in 'feeling a choking lump or swelling of throat' than the farm residents. As the result, I consider that the rural residents were much affected by physical fatigue and pesticides, and the urban, by some problems of industrial fuel, traffic gas and various dusts.
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Summary
- Contents of Health Education for Pupils and the Perceptibility after Graduation of Primary School.
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Bo Yoon Jeon, Doo Hie Kim
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Korean J Prev Med. 1985;18(1):99-112.
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- It was measured to check the state of health education by the survey of the items related to the health with first grade of students in middle school who mastered elementary courses. Totally 50 questions, which were selected from Standard and Dong-A reference books, were given to teachers and have got answered by the students who were totally 959(491 from urban areas and 468 from rural areas). It's done just after they entered middle school for a month, from April 10 to may 10, 1984. There were totally 782 items of health in all subjects of all grades. In contents, the most cases were about mental and emotional health(17.7%), exercise and rest(15.1%), environmental health, health life, personal health care, nutrition and foods, social health and organization, physiology and anatomy, statistics of public health population problem, disease and care, food sanitation, school health, parasitic and communicable disease control, eugenics and heredity(0.4%), etc were followed. In subjects, Korean language had 44.7% of mental emotional health in 114 cases, arithmetics 46.4% of statistics of public health in 26, sociology, 23.1% of environmental health in 118, natural science, 60.1% of physiology and anatomy in 30, ethics, 40.3% of mental and emotional health in 176, music, 21.8% of mental and emotional health and accidents in 23, art, 42.9% of exercise and rest in 28, physical education, 38.6% of exercise and rest in 201, practical course, 36.2% of nutrition and foods in 61, and there was nothing but only one case in Korean history. Subjects in total cases of health informing items are below: Physical education 25.8%, ethics 22.5%, sociology 15.1%, Korean language 14.6%, practical course 7.8%, natural science 3.8%, art 3.6%, arithmetics 3.3%, music 2.9%, Korean history 0.6%. Grades in total cases of health informing items are belows: the sixth grade 29.1%, the fourth grade 21.2%, the fifth grade 18.9%, the third grade 11.6%, the first grade 11.5%, the second grade 7.7%. The sections related to health matters were average 35.4%. According to the grades, the fourth and the sixth grade were 38.2% each other, the highest, and the second grade was 29.3%, the lowest. All sections in physical education included them. The acceptability to the knowledge for health was belows: 56.3% in urban students and 53.9% in rural students. There was some difference in acceptability between two parties (p<0.005).
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Summary
- Complement Activation by Tobacco Infusion.
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Myung Ho Chung, Doo Hie Kim, Tae Ho Chung
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Korean J Prev Med. 1985;18(1):91-98.
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- The capacity of tobacco infusions of Korean cigarettes to activate the complement pathway was investigated in vitro by hemolytic assay. Complement activity was studied using samples of normal rabbit serum incubated at 37 degrees C with tobacco infusions. In all mixtures containing tobacco infusion A, B, C, D, E, F, G, H and I at a concentration of 0.1 : 1, total hemolytic complement showed a progressive decrease of 55.92%, 48.62%, 42.89%, 49.12%, 42.26%, 52.26%, 71.96%, 60.90%, and 61.14% respectively, after 60min of incubation. This study suggests that all tobacco infusions of Korean cigarettes are activators of complement.
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Summary
- Hearing Threshold Shift Level of Weavers on Wearing the Ear Plugs.
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Yeong Hwan Kim, Jong Young Lee, Doo Hie Kim
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Korean J Prev Med. 1984;17(1):57-64.
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Abstract
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- To assess the hearing conservation by the hearing protection devices in the field, 1,237 healthy female weavers of 16 to 24 year old were surveyed from April 1982 to January 1983. By reviewing the charts, their working durations, hearing threshold shift levels and whether wearing the ear plugs or not were checked. The hearing threshold levels were measured at 4,000 Hz by audiometry AA-30A, RION Japan. They were divided into two groups: an experimental group with ear plug and the control group without it. The threshold shift level above 40dB in controls was 44.6% in left and 40.9% in right ear and that in experimental group 8.0% in left and 6.6% in right ear. The distribution of threshold shift levels between control and experimental group was significantly different in both ears, but that between left and right ear not significantly different in both groups. The longer the working durations were, the more the proportion of high threshold shift levels was and the larger the differences in the proportion of above 40dB between both groups were.
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Summary
- Clinical Aspects among Platers.
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Doo Hie Kim
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Korean J Prev Med. 1977;10(1):16-24.
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- This is a result of clinical examination for workers working with Chromic acid and Chromium compounds in the plating room of their companies. I selected two companies that the plating process and the kinds of plating were similar. One (SW Co.) was more or less improved the operating environment with the ventilation machine so on and another (SR Co.) did not it so. The former was examined at March 29th 1977, the latter was at June 28th 1976. But the respiratory communicable diseases, flue or common cold so on were not spreaded there at that time. The clinical aspects were compared between the group of SW, and SR. The swelling and hyperemic signs of nasal mucous membrane and the experience of nasal bleeding were about 50%, generally, in all the groups. The following problem was dizziness or vertigo. The nasal signs in the group SW (improved ventilation of the room air) were relatively weak, but in another, it was come what severe;-there was necrotic sign with thick nasal clast. They were only used of gauze mask when the vapors of various solvents were deeply full in the room. And there was very high rate of bronchial signs, sputum or coughing in the group of SW improved ventilation so called, than another one. I suppose that it means chronic inflammatory change of the bronchial mucous membrane with deeper signs, due to the individual protectors were carelessly or not used according to the improving of the operating environment. Theses nasal signs mentioned the above were not nearly in the other groups had not been done the Chromium plating. The status of RBC, Hb and Ht, of urine protein and urobilinogen were mostly in normal range. But the number of WBC was more or less showed with a positive cor-relation to the working duration.
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Summary
- Skin Diseases of Female Workers in Silk Reeling Industry.
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Doo Hie Kim
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Korean J Prev Med. 1976;9(1):117-122.
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Abstract
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- The occupational skin diseases in an industry of silk reeling located in Daegu city of Korea were analyzed by inspection through a mass survey for improving the workers' health, November, 1975. The subjects, 177 persons were all females, and were distributed at 18-38 years old. About two thirds were under 25 years old. The mean age was 23.6 years. The incidence of skin diseases was about 53%. It was generally divided into groups; -the epidermic changes of those were most frequent, 47.5%, the allergic reactions were 14.7%, and athlete's foot was only four cases, 2.3%. Most frequent signs of epidermic changes was the wornout nail, 32.3%; and the keratolysis, 28.8%; and the callus, 15.3% were followed in order. Theses were significant in five per cent level between the sections of the silk reeling and the manufacturing;-Allergic reactions and worn-out nail were more frequent in the manufacturing group than the silk reeling, and keratolysis and callus were inverted proportionally. Allergic reactions were occurred within a few months from first entrance time, and it was more frequent in the group exposed to same allergen in the past than the continuing group form first. Most of the appearing sites of theses were hands, and infrequently, it was occurred in the face, neck, trunk, knee and feet. These epidermic changes except allergic phenomena were appeared in the fingers, palmal and dorsal surface of hands frequently contacted. But these changes and allergic reactions were generally combined with two or more kinds.
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Summary
- Causes of Sensori-Neural Hearing Impairment in Korean Children.
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Kyu Shik Lee, Young Soon Kim, Do Ha Kwon, Yo Han Kwon, Tae Yung Rhee, Choon Ki Paik, Doo Hie Kim
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Korean J Prev Med. 1976;9(1):55-64.
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- This paper presents the results of a survey for the causes of sensori-neural hearing impairment in Korea. The subjects were 1,676 children of total 2,928 enrolled in 16 Deaf Schools; two schools in each area of Seoul, busan, Kyoungbook, Kyoungna, Kyounggi and Chunbug, and each one in Chungnam, Chungbug, Chunnam and Jaeju. The data were collected by questionnaire with 28 items distributed to their parents. The filling in the check lists were performed by their class teacher, interviewer, for 18 months from September, 1975 to February, 1976. The questionable or missed problems were reaffirmed. The results obtained were as follows. Most of the reasons, 78.5% were acquired characters that could be developed during pregnant period, the time of delivery and the time of after birth. The pure hereditary reasons except the cases complexed with one or two were only 11.3%. Those who could not be defined with any reasons were 10.2%. Among the acquired causes, 5.8% of total subjects were developed for pregnance; 3.3%, during delivery; and 69.7%, after birth. In the pregnant period, the drug intoxications were 2.4% of total subjects, several diseases such as influenza, bleeding, surgical operation, venereal disease and rubella etc. were about one percent, and the accompanied with some symptoms of pregnancy intoxication and traumatic events were 2.4%. During time, the cases with delayed rhythmical pain were 16 persons, the immaturities were 11, the asphyxial cases were nine, the errors of forceps delivery were seven, the cases of low body weight inspite of full term were our, the cases with cesarian section were three, the head injuries were two, and the accompanied with three kinds of above reasons were three. During after birth, the cases with acute communicable diseases were 35.4% of total subjects, the fever unknown origin were 16.1%, the chronic otitis media were 3.7%, the meningitis were 3.5%, the gastric and nutritional diseases were 3.5%, the drug intoxications were 4.8%, the blood diseases were 0.3% and the other causes were 2.2%. Here by acute communicable diseases, some importances were measle, 10.1% of total subjects; meningitis, 7.3%; convulsion with some reasons, 4.9%; poliomyelitis. 3.2%; encephalitis, 2.4%; and mumps, rubella, pertusis, scarlet fever, and small pox were somewhat played a role in. Among 59 cases with brain diseases, 53 were concussion by the accidents, such as traffic and falling or sliping down etc., the cerebral paralysis and hydrocephalus were two, respectively. And the blood diseases were severe newjaundice in all five cases. If we were summarized with the above mentioned, most of the hearing impairments were introduced by the combined reasons with familial or hereditary factors and the acquired, than by a simple disease. Among the congenital or hereditary hearing impairments classified to now a day, we suppose that the many cases with the acquired causes during pregnancy, delivery and after birth were complexed. Subsequently, the maternal and child health should be more and more developed in our country, also.
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Summary
- Bacteriological Mass Survey on Prostitutes for American Soldiers.
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Doo Hie Kim, Young Shik Kim
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Korean J Prev Med. 1975;8(1):83-88.
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Abstract
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- This survey was carried out on about 240 prostitutes for American soldiers in Bong-Deok Venereal Diseases Clinic, Daegu Korea, through 2 times for two months from October and November 1974. The culture method was used identifing Neisseria and Mimeae species carbohidrate fermentation test was ferformed with phenol red broth base added human serum. Resistance test was informed with disc method in chocholete agar plate. The discs were made by Jong-Geon Dang Pham. Co.. Seoul, Korea. The carrierate of Neisseria genorrheae was 9.8% and there were relatively many carriers of Mimeae. If the direct smear is used only in microscopic diagnosis, it is easily confused to differentiate Gonococcus and Mima, a kind of coccobacilli. Gonococcus resistance to penicillin G was found in one out of 5 cases tested. The most of Mimeae was resist to penicillin G, but the broad spectrum antibiotics such as chloramphenico1 and gentamycin etc was moderatly sensitive.
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Summary
- On Effluent Concentration and Time of Fading Out of Carbon Monoxide and Sulful Dioxide in Atmosphere.
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Doo Hie Kim
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Korean J Prev Med. 1974;7(2):373-376.
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Abstract
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- No abstract available.
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Summary
- A Study Concerning Health Needs in Rural Korea.
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Sung Kwan Lee, Doo Hie Kim, Jong Hak Jung, Keuk Soo Chung, Sang Bin Park, Chung Hun Choi, Sun Ho Hong, Jin Hoon Rah
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Korean J Prev Med. 1974;7(1):29-94.
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Abstract
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- Today most developed countries provide modern medical care for most of the population. The rural area is the more neglected area in the medical and health field. In public health, the philosophy is that medical care for in maintenance of health is a basic right of man; it should not be discriminated against racial, environmental or financial situations. The deficiency of the medical care system, cultural bias, economic development, and ignorance of the residents about health care brought about the shortage of medical personnel and facilities on the rural areas. Moreover, medical students and physicians have been taught less about rural health care than about urban health care. Medical care, therefore, is insufficient in terms of health care personnel and facilities in rural areas. Under such a situation, there is growing concern about the health problems among the rural population. the findings presented in this report are useful measures of the major health problems an even more important, as a guide to planning for improves medical care systems. It is hoped that findings from this study will be useful to those responsible for improving the delivery of health service for the rural population. Objectives: -to determine the health status of the residents in the rural area. -to assess the rural population's needs in terms of health and medial care. -to make recommendations concerning improvement in the delivery of health and medical care for the rural population. Procedures: For the sampling design, the ideal would be to sample according to the proportion of the composition age-groups. As the health problems would be different by group , the sample was divided into 10 different age-groups. If the sample were allocated by proportion of composition of each age group, some age groups would be too small to estimate the health problem. The sample size of each age-group population was 100 people/age-groups. Personal interviews were conducted by specially trained medical students. The interviews dealt at length with current health status, medical care problems, utilization of medical services, medical cost paid for medical care and attitudes toward health. In addition, more information was gained from the public health field, including environmental sanitation, maternal and child health, family planning, tuberculosis control, and dental health. The sample: Sample size was one fourth of total population: 1,438. The aged 10-14 years showed the largest number of 254 and the aged under one year was the smallest number of 81. Participation in examination. Examination sessions usually were held in the morning every Tuesday, Wednesday, and Thursday for 3 hours at each session at the Namchun Health station. In general, the rate of participation in medical examination was low especially in ages between 10-19 years old. The highest rate of participation among are groups was the under one year age-group by 100 percent. The lowest use rate as low as 3% of those in the age-groups 10-19 years who are attending junior and senior hgh school in Taegu city so the time was not convenient for them to receive examinations. Among the over 20 years old group, the rate of participation of female was higher than that of males. The results are as follows: A. Public health problems. Population: The number of pre-school age group who required child health was 724, among them infants numbered 96. Number of eligible women aged 15-44 years was 1,279, and women with husband who need maternal health numbered 700. The age-group of 65 years of older was 201 needed more health care and 65 of them had disabilities (table 2). Environmental sanitation: Seventy-nine percent of the residents relied upon well water as a primary source of drinking. More than 90% of latrines were unhygienic, in structure design and sanitation (Table 15). Maternal and child health: Maternal health. Average number of pregnancies of eligible women was 4 times. There was almost no pre-and post-natal care. Pregnancy wastage. Still births was 33 per 1,000 live births. Spontaneous abortion was 156 per 1,000 live births. Induced abortion was 137 per 1,000 live births. Delivery Condition. More than 90 percent of deliveries were conducted at home. Attendants at last delivery were laymen by 76% and delivery without attendants was 14%. The rate of difficult delivery counted for 3%. Maternal death rate estimate about 35 per 10,000 live births. Child health. Consultation rate for child health was almost non existent. In general, vaccination rate of children was low; vaccination rates for children but the rate of the complete three injections were as low as 5 and 3% respectively. The number of dead children was 280 per 1,000 living children. Infants death rate was 45 per 1,000 live births (Table 16). Family planning: Approval rate of married women for family planning was as high as 86%. The rate of experiences of contraception in the past was 51%. The current rate of contraception was 37%. Willingness to use contraception in the future was as high as 86% (Table 17). Tuberculosis control: Number of registration patients at the health center currently was 25. The number indicates one eight of estimate number of tuberculosis in the area. Number of discharged cases in the pat accounted for 79 which showed 50% of active cases when discharged time. Rate of complete treatment among reasons of discharge on the past as low as 28%. There needs to be a follow up observation of the discharged cases (Table 18). Dental Problems: More than 50% of the total population have lest one or more dental problems. (Table 19) B. Medical care Problems. Incidence rate: 1. In one month. Incidence rate of medical care problems during one month was 19.6% percent. Among these health problems which required rest at home were 11.8 percent. The estimated number of patients in the total population is 1,206. The health problems reported most frequently in interviews during one month are: GI trouble, respiratory disease, neuralgia, skin disease, and communicable disease-n the order. The rate of health problems by age groups was highest in the 1-4 age group and in the 60 years of over age group, the lowest rate was the 10-14 year age group. In general, 0-29 year age group except the 1-4 year age group was low incidence rate. After 30 years old th rate of health problems increases gradually with aging. Eighty-three percent of health problems that occurred during one month were solved by primary medical care procedures. Seventeen percent of health problems needed secondary care. Days rested at those because of illness during one month were 1.7days per interviewee and 8days per patient and it accounts for 2,161 days for the total productive population in the area. (Table 20) 2. In a year. The incidence rate of medical care problems during a year was 7.8%, among them health problems which required rest at those was 37 percent. Estimated number of patients in the total population during a year was 4,600. The health problems that occurred most frequently among the interviewees during a year were: Cold (30%), GI trouble (18), respiratory disease (11), anemia (10) ,diarrhea (10), neuralgia (10), parasite disease (9), ENT (7), skin (7), headache (7), trauma (4), communicable disease (3), and circulatory disease (3)-in that order. The rate of health problems by age groups was highest in the infants group, thereafter the rate decreased gradually until the age group which showed the lowest, and then the rate increased gradually with aging. Eighty-seven percent of health problems during a year were 16 days per interviewee and 4 days per patient and it accounted for 57,335 days lost among productive age group in the area (Table 21). Among those given medical examination, the conditions observed most frequency were respiratory disease, GI trouble, parasite disease, neuralgia, skin disease, trauma, tuberculosis, anemia, chronic obstructive lung disease, eye disorders-in that order (Table 22). The main health problems required secondary medical care are as follows:(previous page). Utilization of medical care (treatment) by various medical for all health problems during one month was 73 percent. The rate of receiving of medical care of those who have health problems which required rest at home was 82% while the rate of those who have health problems which did not required rest was 61percent (Table 23). The rate of receiving of medical care for all health problems during a year was 67 percent. The rate of receiving of medical care of those who have health problems which required rest at home was 82 percent while the rate of those who have health problems which did not required rest was as low as 53 percent (Table 24). Types of medical facilitated used were as follows: Hospital and clinics: 32-35%. Herb clinics: 9-10%. Drugstore: 53-58%. Hospitalization. Rate of hospitalization was 1.7% and the estimate number of hospitalization among the total population during a year will be 107 persons (Table 25). Medical cost: Average medical cost per person during one month and a year were 171 and 2,800 won respectively. Average medical cost per patient during one month and a year were 1,1109 and 3,740 won respectively. Average cost per household during a year was 15,800 won (Table 26, 27).Solution measures for health and medical care problems in rural area: A. Health problems which could be solved by paramedical workers such as nurses, midwives and aid nurses etc. are as follows: 1. Improvement of environmental sanitation. 2. MCH except medical care problems. 3. Family planning except surgical intervention. 4. Tuberculosis control except diagnosis and prescription. 5. Dental care except operational intervention. 6. Health education for residents for improvement of utilization of medical facilities and early diagnosis etc. b. Medical care problems. 1. Eighty-five percent of health problems could be solved by primary care procedures by general practitioners. 2. Fifteen percent of health problems need secondary medical procedures by a specialist. C. Medical cost. Considering the economic situation in rural area the amount of 2,062 won per residents during a year will be burdensome, so financial assistance is need government to solve health and medical care problems for rural people.
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Summary
- A Study on Residual Hearing of Hearing Impaired Children.
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Kyu Sjik Lee, Doo Hie Kim
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Korean J Prev Med. 1973;6(1):51-63.
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- This paper illustrate residual hearing and socio-medical background on the hearing impaired children, 207 coming to Deaf School, attached to Hankuk Social Work College, Tague, Korea. The survey was performed through interview with their parents and testing by diagnostic audiometer (TRIO, AS 105 type) at soundproof room from March 10, to November 28, 1973. The results obtained were as follows. 1) The attendance rate of the compulsory primary school was markedly lower tendency in female than according to directly proprotinoal to prevalence rate of deafness amont them, If was showed the deeper gap in the more superior school (middle and high school). 2) Who entered at the suitable age to each school (six years old to primary school, 12 years to middle and 15 years to high) was 11.3%. And who were enrolled in school age to each school (6-11) years for primary. 12-14 years for middle and 15-17 years for high) was 45.9% (43.7% in male, 50.0% in female). 3)As causative disease, congenital case, were 23.6% include of 13.5% of heredity and 10.1% of troubles during pregnancy ; the total acquired cases were 47.9%, it was classified as 11.6% of convulsion from any other diseases, 7.7% of measles, 7.7% of other febrile diseases, 3.4% of drug (the most of streptomycin) intoxication, 2.4% of meningitls, 1.5% of epidemic encephalitis and 31.3% of other diseases ; and unknown cases were 28.5%. 4)31.4% of who included congenital cases lost their hearing within six months old, 11.6% in 6-11 months. 9.7% n 1-2 years old and 14.0% in 2-3years old. Consequently we obtained that the most cases 90.0% were lost their hearing within 3 years after birth.
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Summary
- A Survey on the Hearing Disturbance of High School Students in Korea.
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Kyu Shik Rhee, Doo Hie Kim
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Korean J Prev Med. 1972;5(1):115-123.
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Abstract
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- As a link of chain study program of school health, a survey was made up by the screening test with audiometry for hearing disturbance on 18,675 high school students who are mainly aged in 15-19 years from November 5.1969 to October 30. 1970. The results obtained were summarized as follows. According to our criteria as table 3, the rates of the profound , the severe and the moderate who required the appropriate hearing aids were 0.02%, 0.03% and 0.14% respectively : the cumulative percentage was 0.197. When the marginal, 0.23% should be included the cumulative rate was 0.41%. But there was no significance by sex and school classes. If we will make the special classes for them one class would be estimated out of 10,000 persons when a class is formed with about 15 persons. Otherwise when we examined that according to each ear of persons, the rates of the profound, the severe and the moderate were 0.17%, 0.22% and 0.33% respectively and their cumulative perventage was 0.72. There was no significance also by sex and age. By the way, the rate of hearing disturbance in urban high school students tended to lower than rural. And the perceptive disturbance was higher than rural in rate. The conductive disturbance tended to oppose in comparison with the above.
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Summary
- A Comparison of Side for Termination, and Continuation Rate for Various Kinds of Oral Contraceptive Pill.
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Sung Kwan Lee, Doo Hie Kim, Min Hae Yeh, Soon Ho Hong
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Korean J Prev Med. 1970;3(1):51-96.
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Abstract
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- No abstract available.
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Summary
- On the Change of Basic Characteristics of Korean Rural Woman in Relation to Family Planning.
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Jong Hack Jung, Jung Duck Park, Dong Chul Kim, In Moo Huh, Hyun Sick Lee, Doo Hie Kim
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Korean J Prev Med. 1970;3(1):23-30.
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- The authors compared the basic characteristics of rural woman in relation to family planning for June 1967 and June 1969 in Kyung San Country Kyungpook Province, Korea. The statistics showed that these characteristics are gradually changing. The marriage age was slightly higher than the past year and the formal education of women increased. The ideal children number, and tile gravidity and mortality rates decreased. At the same time the number of induced abortions, the knowledge of family planning, and the acceptance rate of contraception increased. These phenomena seem to follow the present worldwide trend.
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Summary
- A Study in Acceptance of Oral Contraceptives among Women in a Rural Area.
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Sung Kwan Lee, Dae Woo Han, Min Hae Ye, Doo Hie Kim
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Korean J Prev Med. 1969;2(1):23-60.
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- No abstract available.
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Summary
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