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COVID-19: Special Article
COVID-19 International Collaborative Research by the Health Insurance Review and Assessment Service Using Its Nationwide Real-world Data: Database, Outcomes, and Implications
Yeunsook Rho, Do Yeon Cho, Yejin Son, Yu Jin Lee, Ji Woo Kim, Hye Jin Lee, Seng Chan You, Rae Woong Park, Jin Yong Lee
J Prev Med Public Health. 2021;54(1):8-16.   Published online January 26, 2021
DOI: https://doi.org/10.3961/jpmph.20.616
  • 4,603 View
  • 200 Download
  • 10 Web of Science
  • 9 Crossref
AbstractAbstract PDF
This article aims to introduce the inception and operation of the COVID-19 International Collaborative Research Project, the world’s first coronavirus disease 2019 (COVID-19) open data project for research, along with its dataset and research method, and to discuss relevant considerations for collaborative research using nationwide real-world data (RWD). COVID-19 has spread across the world since early 2020, becoming a serious global health threat to life, safety, and social and economic activities. However, insufficient RWD from patients was available to help clinicians efficiently diagnose and treat patients with COVID-19, or to provide necessary information to the government for policy-making. Countries that saw a rapid surge of infections had to focus on leveraging medical professionals to treat patients, and the circumstances made it even more difficult to promptly use COVID-19 RWD. Against this backdrop, the Health Insurance Review and Assessment Service (HIRA) of Korea decided to open its COVID-19 RWD collected through Korea’s universal health insurance program, under the title of the COVID-19 International Collaborative Research Project. The dataset, consisting of 476 508 claim statements from 234 427 patients (7590 confirmed cases) and 18 691 318 claim statements of the same patients for the previous 3 years, was established and hosted on HIRA’s in-house server. Researchers who applied to participate in the project uploaded analysis code on the platform prepared by HIRA, and HIRA conducted the analysis and provided outcome values. As of November 2020, analyses have been completed for 129 research projects, which have been published or are in the process of being published in prestigious journals.
Summary

Citations

Citations to this article as recorded by  
  • Symptoms and Conditions in Children and Adults up to 90 Days after SARS-CoV-2 Infection: A Retrospective Observational Study Utilizing the Common Data Model
    Minjung Han, Taehee Chang, Hae-ryoung Chun, Suyoung Jo, Yeongchang Jo, Dong Han Yu, Sooyoung Yoo, Sung-il Cho
    Journal of Clinical Medicine.2024; 13(10): 2911.     CrossRef
  • Data Resource Profile: Health Insurance Review and Assessment Service Covid-19 Observational Medical Outcomes Partnership (HIRA Covid-19 OMOP) database in South Korea
    Chungsoo Kim, Dong Han Yu, Hyeran Baek, Jaehyeong Cho, Seng Chan You, Rae Woong Park
    International Journal of Epidemiology.2024;[Epub]     CrossRef
  • Effect of changes in the hearing aid subsidy on the prevalence of hearing loss in South Korea
    Chul Young Yoon, Junhun Lee, Tae Hoon Kong, Young Joon Seo
    Frontiers in Neurology.2023;[Epub]     CrossRef
  • Scalable Infrastructure Supporting Reproducible Nationwide Healthcare Data Analysis toward FAIR Stewardship
    Ji-Woo Kim, Chungsoo Kim, Kyoung-Hoon Kim, Yujin Lee, Dong Han Yu, Jeongwon Yun, Hyeran Baek, Rae Woong Park, Seng Chan You
    Scientific Data.2023;[Epub]     CrossRef
  • Comparative risk of incidence and clinical outcomes of COVID-19 among proton pump inhibitor and histamine-2 receptor antagonist short-term users: a nationwide retrospective cohort study
    Jimyung Park, Seng Chan You, Jaehyeong Cho, Chan Hyuk Park, Woon Geon Shin, Rae Woong Park, Seung In Seo
    BMC Pharmacology and Toxicology.2022;[Epub]     CrossRef
  • Decreased patient visits for ankle sprain during the COVID-19 pandemic in South Korea: A nationwide retrospective study
    Youngsik Hwang, Dasom Kim, Sukhyun Ryu
    Preventive Medicine Reports.2022; 26: 101728.     CrossRef
  • Early Real-World Data to Assess Benefits and Risks of COVID-19 Vaccines: A Systematic Review of Methods
    Tatiane B. Ribeiro, Fátima Roque, Fidelia Ida, Ana I. Plácido, Mai Vu, Jose J. Hernández-Muñoz, Maria Teresa Herdeiro
    Vaccines.2022; 10(11): 1896.     CrossRef
  • Challenges in evaluating treatments for COVID-19: The case of in-hospital anticoagulant use and the risk of adverse outcomes
    Ya-Hui Yu, In-Sun Oh, Han Eol Jeong, Robert W. Platt, Antonios Douros, Ju-Young Shin, Kristian B. Filion
    Frontiers in Pharmacology.2022;[Epub]     CrossRef
  • Use of repurposed and adjuvant drugs in hospital patients with covid-19: multinational network cohort study
    Albert Prats-Uribe, Anthony G Sena, Lana Yin Hui Lai, Waheed-Ul-Rahman Ahmed, Heba Alghoul, Osaid Alser, Thamir M Alshammari, Carlos Areia, William Carter, Paula Casajust, Dalia Dawoud, Asieh Golozar, Jitendra Jonnagaddala, Paras P Mehta, Mengchun Gong, D
    BMJ.2021; : n1038.     CrossRef
Perspective
Dilemmas Within the Korean Health Insurance System
Donghwi Park, Min Cheol Chang
J Prev Med Public Health. 2020;53(4):285-288.   Published online July 1, 2020
DOI: https://doi.org/10.3961/jpmph.20.074
  • 4,337 View
  • 118 Download
  • 3 Crossref
AbstractAbstract PDF
The health insurance system in Korea is well-established and provides benefits for the entire national population. In Korea, when patients are treated at a hospital, the hospital receives a partial payment for the treatment from the patient, and the remaining amount is provided by the health insurance service. The Health Insurance Review and Assessment Service (HIRA) assesses whether the treatment was appropriate. If HIRA deems the treatment appropriate, the doctor can receive payment from the health insurance service. However, this system has several drawbacks. In this study, we aimed to provide examples of the problems that can occur in relation to HIRA assessments in Korea through actual clinical cases.
Summary

Citations

Citations to this article as recorded by  
  • The Paradox of the Ugandan Health Insurance System: Challenges and Opportunities for Health Reform
    Emmanuel Otieno, Josephine Namyalo
    Journal of Preventive Medicine and Public Health.2024; 57(1): 91.     CrossRef
  • Effect of Income Level on Stroke Incidence and Mediated Effects of Medication Adherence in Newly Diagnosed Hypertensive Patients: A Causal Mediation Analysis Using a Nationwide Cohort Study in South Korea
    Seungmin Jeong, So Yeon Kong, Seung-sik Hwang, Sung-il Cho
    Journal of Health Informatics and Statistics.2022; 47(4): 268.     CrossRef
  • Diagnosis of Duchenne Muscular Dystrophy in a Presymptomatic Infant Using Next-Generation Sequencing and Chromosomal Microarray Analysis: A Case Report
    Eun-Woo Park, Ye-Jee Shim, Jung-Sook Ha, Jin-Hong Shin, Soyoung Lee, Jang-Hyuk Cho
    Children.2021; 8(5): 377.     CrossRef
Original Article
Prescription of Systemic Steroids for Acute Respiratory Infections in Korean Outpatient Settings: Overall Patterns and Effects of the Prescription Appropriateness Evaluation Policy
Taejae Kim, Young Kyung Do
J Prev Med Public Health. 2020;53(2):82-88.   Published online November 18, 2019
DOI: https://doi.org/10.3961/jpmph.19.090
  • 8,417 View
  • 141 Download
  • 5 Crossref
AbstractAbstract AbstractSummary PDF
Objectives
The objective of this study was to identify individual and institutional factors associated with the prescription of systemic steroids in patients with acute respiratory infections and to investigate the role of a policy measure aimed to reduce inappropriate prescriptions. Methods: We used data from the National Health Insurance Service-National Sample Cohort from 2006 to 2015 and focused on episodes of acute respiratory infection. Descriptive analysis and multiple logistic regression analysis were performed to identify individual-level and institution-level factors associated with the prescription of systemic steroids. In addition, steroid prescription rates were compared with antibiotic prescription rates to assess their serial trends in relation to Health Insurance Review and Assessment Service (HIRA) Prescription Appropriateness Evaluation policy. Results: Among a total of 9 460 552 episodes of respiratory infection, the steroid prescription rate was 6.8%. Defined daily doses/1000 persons/d of steroid increased gradually until 2009, but rose sharply since 2010. The steroid prescription rate was higher among ear, nose and throat specialties (13.0%) than other specialties, and in hospitals (8.0%) than in tertiary hospitals (3.0%) and other types of institutions. Following a prolonged reduction in the steroid prescription rate, this rate increased since the HIRA Prescription Appropriateness Evaluation dropped steroids from its list of evaluation items in 2009. Such a trend reversal was not observed for the prescription rate of antibiotics, which continue to be on the HIRA Prescription Appropriateness Evaluation list. Conclusions: Specialty and type of institution are important correlates of steroid prescriptions in cases of acute respiratory infection. Steroid prescriptions can also be influenced by policy measures, such as the HIRA Prescription Appropriateness Evaluation policy.
Summary
Korean summary
이 연구에서는 요양급여 청구자료를 기준으로 급성 상기도 감염에서 스테로이드를 처방하는 경우와 관련하여 다음과 같은 특징을 확인하였다. 첫째, 환자 특성과 기관 특성을 모두 고려하였을 때 진료과목과 기관의 종별 구분에서 감기 스테로이드 처방률은 상당한 변이를 보였다. 둘째, 약제급여적정성평가 항목에서 스테로이드가 제외된 직후 처방률이 시계열적으로 상승하였으며, 이는 처방 행태에 정책 요인이 중요한 영향을 미칠 수 있음을 뜻한다.

Citations

Citations to this article as recorded by  
  • Measurement of Ambulatory Medication Errors in Children: A Scoping Review
    Lisa Rickey, Katherine Auger, Maria T. Britto, Isabelle Rodgers, Shayna Field, Alayna Odom, Madison Lehr, Alexandria Cronin, Kathleen E. Walsh
    Pediatrics.2023;[Epub]     CrossRef
  • Trends and Patterns of Systemic Glucocorticoid Prescription in Primary Care Institutions in Southwest China, from 2018 to 2021
    Xiaoyi Li, Zhen Zeng, Xingying Fan, Wenju Wang, Xiaobo Luo, Junli Yang, Yue Chang
    Risk Management and Healthcare Policy.2023; Volume 16: 2849.     CrossRef
  • Effects of monthly evaluations on the rates of irrational antimicrobial prescription in the outpatient and emergency departments at Ningbo No. 6 Hospital, Ningbo, China
    Qiong Yang, Fangfang Yuan, Li Li, Jianfeng Jin, Junhong He
    European Journal of Medical Research.2022;[Epub]     CrossRef
  • Systemic glucocorticoid prescriptions pattern and factors of inappropriate use in primary care institutions of Southwest China
    Xiaobo Luo, Shitao Yu, Zhen Zeng, Xunrong Zhou, Yuxi Liu, Lei Wang, Jiaqi Hu, Yue Chang
    Frontiers in Public Health.2022;[Epub]     CrossRef
  • Effects of Antiviral Therapy and Glucocorticoid Therapy on Fever Duration in Pediatric Patients with Influenza
    Ji Yoon Han, Eun Ae Yang, Jung-Woo Rhim, Seung Beom Han
    Medicina.2021; 57(12): 1385.     CrossRef

JPMPH : Journal of Preventive Medicine and Public Health