Objectives A growing number of people depend on flexible employment, characterized by outsider employment status and perceived job insecurity. This study investigated whether there was a synergistic effect of employment status (full-time vs. part-time) and perceived job insecurity on major depressive disorder.
Methods Data were derived from the 2012 Canadian Community Health Survey-Mental Health of 12 640 of Canada’s labor force population, aged 20 to 74. By combining employment status with perceived job insecurity, we formed four employment categories: fulltime secure, full-time insecure, part-time secure, and part-time insecure.
Results Results showed no synergistic health effect between employment status and perceived job insecurity. Regardless of employment status (full-time vs. part-time), insecure employment was significantly associated with a high risk of major depressive disorder. Analysis of the interaction between gender and four flexible employment status showed a gender-contingent effect on this link in only full-time insecure category. Men workers with full-time insecure jobs were more likely to experience major depressive disorders than their women counterparts.
Conclusions This study’s findings imply that perceived job insecurity may be a critical factor for developing major depressive disorder, in both men and women workers.
Summary
Korean summary
본 연구는 CCHS-MH (2012) 자료를 이용하여 비정규직과 주관적 고용불안정성이 우울장애에 미치는 시너지 효과를 분석하였다. 연구결과 비정규직 여부와 무관하게, 주관적 고용불안정성은 우울장애와의 연관성이 유의하게 높았다. 특히 정규직 여성보다 정규직 남성에서 주관적 고용불안정성과 우울장애의 연관성이 유의하게 높았다. 이 연구결과는 비정규직 여부보다 주관적 고용불안정성이 주요우울장애에 더 큰 영향요인임을 제시하고 있다.
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Objectives Previous epidemiological studies about oxidative stress and depression are limited by hospital-based case-control design, single-time measurements of oxidative stress biomarkers, and the small number of study participants. Therefore, in this study, we analyzed the association between biomarker of oxidative stress and depressive symptom scores using repeatedly measured panel data from a community-dwelling elderly population.
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Results A two-fold increase in urinary MDA concentration was significantly associated with a 33.88% (95% confidence interval [CI], 21.59% to 47.42%) increase in total SGDS-K scores. In subgroup analyses by gender, a two-fold increase in urinary MDA concentration was significantly associated with increased SGDS-K scores in both men and women (men: 30.88%; 95% CI, 10.24% to 55.37%; women: 34.77%; 95% CI, 20.09% to 51.25%). In bivariate analysis after an SGDS-K score ≥8 was defined as depression, the third and the fourth urinary MDA quartiles showed a significantly increased odds ratio(OR) of depression compared to the lowest urinary MDA quartile (third quartile OR, 6.51; 95% CI, 1.77 to 24.00; fourth quartile OR, 7.11; 95% CI, 1.99 to 25.42).
Conclusions Our study suggests a significant association between oxidative stress and depressive symptoms in the elderly population.
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