- Interaction of Body Mass Index and Diabetes as Modifiers of Cardiovascular Mortality in a Cohort Study
-
Seung Hyun Ma, Bo-Young Park, Jae Jeong Yang, En-Joo Jung, Yohwan Yeo, Yungi Whang, Soung-Hoon Chang, Hai-Rim Shin, Daehee Kang, Keun-Young Yoo, Sue Kyung Park
-
J Prev Med Public Health. 2012;45(6):394-401. Published online November 29, 2012
-
DOI: https://doi.org/10.3961/jpmph.2012.45.6.394
-
-
10,558
View
-
94
Download
-
13
Crossref
-
 Abstract
 PDF
- Objectives
Diabetes and obesity each increases mortality, but recent papers have shown that lean Asian persons were at greater risk for mortality than were obese persons. The objective of this study is to determine whether an interaction exists between body mass index (BMI) and diabetes, which can modify the risk of death by cardiovascular disease (CVD). MethodsSubjects who were over 20 years of age, and who had information regarding BMI, past history of diabetes, and fasting blood glucose levels (n=16 048), were selected from the Korea Multi-center Cancer Cohort study participants. By 2008, a total of 1290 participants had died; 251 and 155 had died of CVD and stroke, respectively. The hazard for deaths was calculated with hazard ratio (HR) and 95% confidence interval (95% CI) by Cox proportional hazard model. ResultsCompared with the normal population, patients with diabetes were at higher risk for CVD and stroke deaths (HR, 1.84; 95% CI, 1.33 to 2.56; HR, 1.82; 95% CI, 1.20 to 2.76; respectively). Relative to subjects with no diabetes and normal BMI (21 to 22.9 kg/m2), lean subjects with diabetes (BMI <21 kg/m2) had a greater risk for CVD and stroke deaths (HR, 2.83; 95% CI, 1.57 to 5.09; HR, 3.27; 95% CI, 1.58 to 6.76; respectively), while obese subjects with diabetes (BMI ≥25 kg/m2) had no increased death risk (p-interaction <0.05). This pattern was consistent in sub-populations with no incidence of hypertension. ConclusionsThis study suggests that diabetes in lean people is more critical to CVD deaths than it is in obese people.
-
Summary
-
Citations
Citations to this article as recorded by  - Development and validation of multicentre study on novel Artificial Intelligence-based Cardiovascular Risk Score (AICVD)
Shiv Kumar Jalepalli, Prashant Gupta, Andre L A J Dekker, Inigo Bermejo, Sujoy Kar
Family Medicine and Community Health.2024; 12(Suppl 1): e002340. CrossRef - The expanding roles of neuronal nitric oxide synthase (NOS1)
Kundan Solanki, Sajjan Rajpoot, Evgeny E. Bezsonov, Alexander N. Orekhov, Rohit Saluja, Anita Wary, Cassondra Axen, Kishore Wary, Mirza S. Baig
PeerJ.2022; 10: e13651. CrossRef - Obesity and metabolic outcomes in a safety-net health system
Michael P. Huynh, Patrick T. Bradshaw, Michele M. Tana, Carly Rachocki, Ma Somsouk
Biodemography and Social Biology.2020; 65(3): 257. CrossRef - Lifestyle Factors and Gender-Specific Risk of Stroke in Adults with Diabetes Mellitus: A Case-Control Study
Jian Guo, Tianjia Guan, Ying Shen, Baohua Chao, Mei Li, Longde Wang, Yuanli Liu
Journal of Stroke and Cerebrovascular Diseases.2018; 27(7): 1852. CrossRef - Nonlinear association of BMI with all-cause and cardiovascular mortality in type 2 diabetes mellitus: a systematic review and meta-analysis of 414,587 participants in prospective studies
Francesco Zaccardi, Nafeesa N. Dhalwani, Dimitris Papamargaritis, David R. Webb, Gavin J. Murphy, Melanie J. Davies, Kamlesh Khunti
Diabetologia.2017; 60(2): 240. CrossRef - Determinants of mortality in patients with type 2 diabetes: a review
Jana Engelmann, Ulf Manuwald, Constanze Rubach, Joachim Kugler, Andreas L. Birkenfeld, Markolf Hanefeld, Ulrike Rothe
Reviews in Endocrine and Metabolic Disorders.2016; 17(1): 129. CrossRef - Analysis between nitric oxide synthase 1 (NOS1) and risk of obesity
Hyun Kyung Park, Su Kang Kim, Oh Young Kwon, Joo-Ho Chung, Seong-Kyu Lee
Molecular & Cellular Toxicology.2016; 12(2): 217. CrossRef - Association between different obesity measures and the risk of stroke in the EPIC Spanish cohort
Itziar Abete, Larraitz Arriola, Nerea Etxezarreta, Imanol Mozo, Conchi Moreno-Iribas, Pilar Amiano, Nerea Egüés, Estibaliz Goyenechea, Adolfo Lopez de Munain, Maite Martinez, Noemi Travier, Carmen Navarro, Maria-Dolores Chirlaque, Maria-Jose Tormo, Diana
European Journal of Nutrition.2015; 54(3): 365. CrossRef - Relationship of body mass index and abdominal obesity in rural population of Krasnodarsky kray taken
Elena V. Bolotova, Irina V. Samorodskaya, Irina M. Komissarova
Obesity and metabolism.2015; 13(1): 25. CrossRef - Associations of prediabetes with all-cause and cardiovascular mortality: A meta-analysis
Yi Huang, Xiaoyan Cai, Peisong Chen, Weiyi Mai, Hongfeng Tang, Yuli Huang, Yunzhao Hu
Annals of Medicine.2014; 46(8): 684. CrossRef - High Peritoneal Transport Status Was Not Associated with Mortality in Peritoneal Dialysis Patients with Diabetes
Naya Huang, Jiehui Chen, Li Fan, Qian Zhou, Qingdong Xu, Ricong Xu, Liping Xiong, Xueqing Yu, Haiping Mao, Zhanjun Jia
PLoS ONE.2014; 9(10): e110445. CrossRef - Body Mass Index and Mortality Among Japanese Patients With Type 2 Diabetes: Pooled Analysis of the Japan Diabetes Complications Study and the Japanese Elderly Diabetes Intervention Trial
Shiro Tanaka, Sachiko Tanaka, Satoshi Iimuro, Yasuo Akanuma, Yasuo Ohashi, Nobuhiro Yamada, Atsushi Araki, Hideki Ito, Hirohito Sone
The Journal of Clinical Endocrinology & Metabolism.2014; 99(12): E2692. CrossRef - Validação cruzada entre o percentual de gordura mensurado pela absortometria radiológica de dupla energia e a equação de Deurenberg em idosas
Piettra Moura Galvão-Pereira, Giselma Alcantara-Silva, Adriano Eduardo Lima-Silva, Dante Wanderley Lima, Amandio Aristides Rihan Geraldes
Revista Brasileira de Geriatria e Gerontologia.2013; 16(4): 681. CrossRef
- Alcohol Consumption and Mortality in the Korean Multi-center Cancer Cohort Study
-
En-Joo Jung, Aesun Shin, Sue K. Park, Seung-Hyun Ma, In-Seong Cho, Boyoung Park, Eun-Ha Lee, Soung-Hoon Chang, Hai-Rim Shin, Daehee Kang, Keun-Young Yoo
-
J Prev Med Public Health. 2012;45(5):301-308. Published online September 28, 2012
-
DOI: https://doi.org/10.3961/jpmph.2012.45.5.301
-
-
12,380
View
-
106
Download
-
16
Crossref
-
Abstract
PDF
- Objectives
To examine the association between alcohol consumption habit, types of beverages, alcohol consumption quantity, and overall and cancer-specific mortality among Korean adults. MethodsThe alcohol consumption information of a total of 16 320 participants who were 20 years or older from the Korean Multi-center Cancer Cohort were analyzed to examine the association between alcohol consumption habit and mortality (median follow-up of 9.3 years). The Cox proportional hazard model was used to estimate the hazard ratio (HR) of alcohol consumption to mortality adjusting for age, sex, geographic areas, education, smoking status, and body mass index. ResultsAlcohol drinkers showed an increased risk for total mortality compared with never drinkers (HR, 1.72; 95% confidence interval [CI], 1.38 to 2.14 for past drinkers; HR, 1.21; 95% CI, 1.06 to 1.39 for current drinkers), while past drinkers only were associated with higher risk for cancer deaths (HR, 1.84; 95% CI, 1.34 to 2.53). The quantity of alcohol consumed per week showed a J-shaped association with risk of mortality. Relative to light drinkers (0.01 to 90 g/wk), never drinkers and heavy drinkers (>504 g/wk) had an increased risk for all-cause and cancer deaths: (HR, 1.18; 95% CI, 0.96 to 1.45) and (HR, 1.39; 95% CI, 1.05 to 1.83) for all-cause mortality; and (HR, 1.55; 95% CI, 1.15 to 2.11) and (HR, 2.07; 95% CI, 1.39 to 3.09) for all cancer mortality, respectively. Heavy drinkers (>504 g/wk) showed an elevated risk for death from stomach and liver cancers. ConclusionsThe present study supports the existence of a J-shaped association between alcohol consumption quantity and the risk of all-cause and cancer deaths. Heavy drinkers had an increased risk of death from cancer overall and liver and stomach cancer.
-
Summary
-
Citations
Citations to this article as recorded by - Alcohol consumption messages in Korean dramas: the globalization of South Korean drinking norms
Rubini Pasupathy, Jaesook Gho, Brittany Duhart, Courtney Queen
Global Health Promotion.2022; 29(3): 57. CrossRef - Effect of preoperative psychiatric morbidity on postoperative outcomes of lung cancer surgery: A nationwide cohort study in South Korea
In-Ae Song, Hye Yoon Park, Tak Kyu Oh
Journal of Psychosomatic Research.2022; 161: 111002. CrossRef - Alcohol, salud y enfermedad cardiovascular
J. Masip, J.R. Germà Lluch
Revista Clínica Española.2021; 221(6): 359. CrossRef - Alcohol, health and cardiovascular disease
J. Masip, J.R. Germà Lluch
Revista Clínica Española (English Edition).2021; 221(6): 359. CrossRef - Systematic Review with Meta-Analysis: Low-Level Alcohol Consumption and the Risk of Liver Cancer
Hana Park, Seung Kak Shin, Ijin Joo, Do Seon Song, Jeong Won Jang, Joong-Won Park
Gut and Liver.2020; 14(6): 792. CrossRef - Alcohol consumption and gastric cancer risk in Korea: a case-control study
Mi Hui Kim, Shin Ah Kim, Chan Hyuk Park, Chang Soo Eun, Dong Soo Han, Yong Sung Kim, Kyu Sang Song, Bo Youl Choi, Hyun Ja Kim
Nutrition Research and Practice.2019; 13(5): 425. CrossRef - Alcoholic Liver Disease Is Associated with an Increased Risk of Gastric Cancer
Tae Hoon Ha, Byeong Gwan Kim, Donghyong Jeong, Sohee Oh, Won Kim, Yong Jin Jung, Dong Won Ahn, Ji Bong Jeong, Ji Won Kim, Kook Lae Lee, Seong-Joon Koh
Digestive Diseases and Sciences.2017; 62(1): 273. CrossRef - Alcohol Abuse Decreases Pelvic Control and Survival in Cervical Cancer
Jyoti Mayadev, Chin-Shang Li, Jihoon Lim, Richard Valicenti, Edwin A. Alvarez
American Journal of Clinical Oncology.2017; 40(5): 451. CrossRef - Alcohol consumption and gastric cancer risk: a meta-analysis of prospective cohort studies
Xue Han, Li Xiao, Yao Yu, Yu Chen, Hai-Hua Shu
Oncotarget.2017; 8(47): 83237. CrossRef - Association between alcohol consumption and the risk of gastric cancer: a meta-analysis of prospective cohort studies
Zheng He, Ting-Ting Zhao, Hui-Mian Xu, Zhen-Ning Wang, Ying-Ying Xu, Yong-Xi Song, Zhong-Ran Ni, Hao Xu, Song-Cheng Yin, Xing-Yu Liu, Zhi-Feng Miao
Oncotarget.2017; 8(48): 84459. CrossRef - Alcohol consumption and liver cancer risk: a meta-analysis
Shu-Chun Chuang, Yuan-Chin Amy Lee, Guo-Jie Wu, Kurt Straif, Mia Hashibe
Cancer Causes & Control.2015; 26(9): 1205. CrossRef - The relationship between mild alcohol consumption and mortality in Koreans: a systematic review and meta-analysis
Ji-Eun Park, Tae-young Choi, Yeonhee Ryu, Sung-Il Cho
BMC Public Health.2015;[Epub] CrossRef - Association Between Alcohol Consumption and Risk of Cardiovascular Disease and All-Cause Mortality in Patients With Hypertension: A Meta-Analysis of Prospective Cohort Studies
Chao Huang, Jian Zhan, Yu-Jian Liu, De-Jia Li, Su-Qing Wang, Qi-Qiang He
Mayo Clinic Proceedings.2014; 89(9): 1201. CrossRef - Attributable fraction of alcohol consumption on cancer using population-based nationwide cancer incidence and mortality data in the Republic of Korea
Sohee Park, Hai-Rim Shin, Boram Lee, Aesun Shin, Kyu-Won Jung, Duk-Hee Lee, Sun Ha Jee, Sung-Il Cho, Sue Kyung Park, Mathieu Boniol, Paolo Boffetta, Elisabete Weiderpass
BMC Cancer.2014;[Epub] CrossRef - Alcohol and liver cancer: a systematic review and meta-analysis of prospective studies
F. Turati, C. Galeone, M. Rota, C. Pelucchi, E. Negri, V. Bagnardi, G. Corrao, P. Boffetta, C. La Vecchia
Annals of Oncology.2014; 25(8): 1526. CrossRef - Alcohol Consumption and Viral Load Are Synergistically Associated with CIN1
Kyung-Jin Min, Jae-Kwan Lee, Sanghoon Lee, Mi Kyung Kim, Rui Medeiros
PLoS ONE.2013; 8(8): e72142. CrossRef
|
KSPM
