Hepatitis C infection is responsible for high morbidity and mortality rates globally as well as for significant indirect costs. The disease burden caused by the hepatitis C virus (HCV) is comparable to the one caused by human immunodeficiency virus or tuberculosis. Today, simple detection methods, highly effective and easy to administer therapies and efficient preventative measures are available to combat hepatitis C. Nevertheless, in most countries around the world, the World Health Organization target of eliminating this infectious disease and its consequences by 2030 are not being met. Significant gaps in care for hepatitis C sufferers still exist, the shortcomings ranging from education and treatment to aftercare. Hepatitis C infection was and still is not on the radar of most politicians and health authorities. National programmes and strategies to combat the disease exist or are being developed in many countries. However, for these to be implemented efficiently and successfully, clear political commitment, strong civil society actors, well-functioning public health structures and the relevant support from global donors are needed.
Summary
Citations
Citations to this article as recorded by
The Global Burden of Cirrhosis and Other Chronic Liver Diseases in 2021 Ethan Kai Jun Tham, Darren Jun Hao Tan, Pojsakorn Danpanichkul, Cheng Han Ng, Nicholas Syn, Benjamin Koh, Ryan Yan Zhe Lim, Karn Wijarnpreecha, Magaret Li Peng Teng, Benjamin Kai Yi Nah, Benedix Kuan Loo Sim, Xianda Cheng, Zixuan Zhang, Kartik Mitra, Toru Liver International.2025;[Epub] CrossRef
Opportunities and challenges for the application of artificial intelligence paradigms into the management of endemic viral infections: The example of Chronic Hepatitis C Virus Ahmed N. Farrag, Ahmed M. Kamel, Iman A. El‐Baraky Reviews in Medical Virology.2024;[Epub] CrossRef
Barriers and advocacy needs for hepatitis C services in prisons: Informing the prisons hepatitis C advocacy toolkit Shelley J Walker, Lok B Shrestha, Andrew R Lloyd, Olivia Dawson, Yumi Sheehan, Julia Sheehan, Nonso B C Maduka, Joaquin Cabezas, Matthew J Akiyama, Nadine Kronfli International Journal of Drug Policy.2024; 126: 104386. CrossRef
Contemporary Insights into Hepatitis C Virus: A Comprehensive Review Malik Sallam, Roaa Khalil Microorganisms.2024; 12(6): 1035. CrossRef
A Systematic Literature Review and Meta-Analysis of Primary Evidence Reporting Health-State Preference Values in Chronic Hepatitis B, C, and D Ankita Kaushik, Chong Hoon Kim, Sarah Hofmann, Maria João Janeiro, Andrew Lloyd, Filipa Aragão Value in Health.2024;[Epub] CrossRef
Reduced injection risk behavior with co-located hepatitis C treatment at a syringe service program: The accessible care model Claire So Jeong Lee, Pedro Mateu-Gelabert, Yesenia Aponte Melendez, Chunki Fong, Shashi N. Kapadia, Melinda Smith, Kristen M. Marks, Benjamin Eckhardt, Jason T. Blackard PLOS ONE.2024; 19(8): e0308102. CrossRef
A comparison of sofosbuvir/velpatasvir and glecaprevir/pibrentasvir for the treatment of hepatitis C infection among people who inject drugs Shana Yi, David Truong, Brian Conway Journal of Virus Eradication.2024; 10(3): 100388. CrossRef
Prospective approaches to target bovine viral diarrhea virus and hepatitis C virus using miRNA-based inhibitors Shazia Tabassum Hakim, Cayatineto HW Journal of Human Virology & Retrovirology.2024; 11(1): 36. CrossRef
Reducing health inequalities for marginalised populations by improving access to hepatitis C virus testing and treatment Eugenia Lindile Moyo-Hlahla Primary Health Care.2024;[Epub] CrossRef
Metagenomic Detection of Divergent Insect- and Bat-Associated Viruses in Plasma from Two African Individuals Enrolled in Blood-Borne Surveillance Gregory S. Orf, Ana Olivo, Barbara Harris, Sonja L. Weiss, Asmeeta Achari, Guixia Yu, Scot Federman, Dora Mbanya, Linda James, Samuel Mampunza, Charles Y. Chiu, Mary A. Rodgers, Gavin A. Cloherty, Michael G. Berg Viruses.2023; 15(4): 1022. CrossRef
Gastrointestinal tract and viral pathogens Gowthami Sai Kogilathota Jagirdhar, Yashwitha Sai Pulakurthi, Himaja Dutt Chigurupati, Salim Surani World Journal of Virology.2023; 12(3): 136. CrossRef
Hepatitis C virus seroprevalence, testing, and treatment capacity in public health facilities in Ghana, 2016–2021; A multi-centre cross-sectional study Yvonne Ayerki Nartey, Rafiq Okine, Atsu Seake-Kwawu, Georgia Ghartey, Yaw Karikari Asamoah, Ampem Darko Jnr Siaw, Kafui Senya, Amoako Duah, Alex Owusu-Ofori, Opei Adarkwa, Seth Agyeman, Sally Afua Bampoh, Lindsey Hiebert, Henry Njuguna, Neil Gupta, John W PLOS ONE.2023; 18(6): e0287580. CrossRef
Association of NK Cells with the Severity of Fibrosis in Patients with Chronic Hepatitis C Anna Kleczka, Bogdan Mazur, Krzysztof Tomaszek, Andrzej Gabriel, Radosław Dzik, Agata Kabała-Dzik Diagnostics.2023; 13(13): 2187. CrossRef
Rapid and sensitive LAMP/CRISPR-powered diagnostics to detect different hepatitis C virus genotypes using an ITO-based EG-FET biosensing platform Hsin-Ying Ho, Wei-Sin Kao, Piyush Deval, Chia-Yen Dai, Yen-Hsu Chen, Ming-Lung Yu, Che-Hsin Lin, Ling-Shan Yu Sensors and Actuators B: Chemical.2023; 394: 134278. CrossRef
Hepatitis C and hepatocellular carcinoma in Latin America: Elimination as a path to cancer prevention Spencer Goble, Angelo Z. Mattos, Manuel Mendizabal, Jose D. Debes Annals of Hepatology.2023; 28(6): 101149. CrossRef
Self-awareness of hepatitis C infection in the United States: A cross-sectional study based on the National Health Nutrition and Examination Survey Karthik Gnanapandithan, Maged P. Ghali, Yury E. Khudyakov PLOS ONE.2023; 18(10): e0293315. CrossRef
The Prevalence of Transfusion-Transmitted Diseases Among Blood Donors in the Central Blood Bank in Makkah, Saudi Arabia Mohammad Albshri, Palanisamy Manikandan, Mamdouh Allahyani, Abdulelah Aljuaid, Mazen M Almehmadi, Kamal Alzabeedi, Mohamed Babalgaith, Mosa Alghamdi, Faris Alharbi, Mohammed Alhazmi Cureus.2023;[Epub] CrossRef
Assessment of the influence of vitamin D level on the course of chronic hepatitis C in comorbidity with chronic pancreatitis M.A. Derbak, O.V. Buchok, T.M. Ganych, O.A. Rishko, V.V. Timashev INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine).2023; 19(7): 478. CrossRef
Real-world treatment outcome of direct-acting antivirals and patient survival rates in chronic hepatitis C virus infection in Eritrea Ghirmay Ghebrekidan Ghebremeskel, Michael Berhe Solomon, Oliver Okoth Achila, Samuel Tekle Mengistu, Rahel Frezghi Asmelash, Araia Berhane Mesfin, Mohammed Elfatih Hamida Scientific Reports.2023;[Epub] CrossRef
DYNAMICS IN MAIN CLINICAL AND IMMUNOLOGICAL INDICATORS IN PATIENTS WITH COMORBIDITY OF CHRONIC HEPATITIS C AND CHRONIC PANCREATITIS FOLLOWING INTEGRATED THERAPY INCLUDING VITAMIN D M.A. Derbak, O.V. Buchok, O.O. Boldizhar, O.A. Rishko, M.M. Bletskan Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії.2023; 23(4): 84. CrossRef
PECULIARITIES OF THE FUNCTIONAL STATE OF THE LIVER IN PATIENTS WITH CHRONIC HEPATITIS C IN THE PRESENCE OF CHRONIC PANCREATITIS Mariya A. Derbak, Olha V. Buchok, Taras M. Ganich, Mariya V. Rivis, Yana V. Lazur, Viktoriya M. Polyak-Tovt, Volodymyr V. Timashev Wiadomości Lekarskie.2023; 76(11): 2359. CrossRef
Impact of the direct acting antivirals on chronic hepatitis C prevalence on the Swiss organ transplantation list: a retrospective analysis Luis Falcato, Simone Temperli, Philip Bruggmann, Franz Immer Exploration of Digestive Diseases.2023; 2(6): 297. CrossRef
ВИВЧЕННЯ ЕФЕКТИВНОСТІ ВІТАМІНУ D В СКЛАДІ КОМПЛЕКСНОЇ ТЕРАПІЇ ХРОНІЧНОГО ГЕПАТИТУ С ПОЄДНАНОГО З ХРОНІЧНИМ ПАНКРЕАТИТОМ Ольга Бучок , М. Дербак Grail of Science.2023; (34): 360. CrossRef
Impact of the direct acting antivirals on chronic hepatitis C prevalence on the Swiss organ transplantation list: a retrospective analysis Luis Falcato, Simone Temperli, Philip Bruggmann, Franz Immer Exploration of Digestive Diseases.2023;[Epub] CrossRef
THE EFFECT OF COMPLEX THERAPY INCLUDING VITAMIN D ON THE QUALITY OF LIFE OF PATIENTS WITH CHRONIC HEPATITIS C COMBINED WITH CHRONIC PANCREATITIS M. A. Derbak, O. V. Buchok, O. O. Boldizhar, M. M. Bletskan, V. V. Svistak Bulletin of Problems Biology and Medicine.2023; 1(2): 166. CrossRef
Intrafamilial transmission risk factors and preventive measures followed by household contacts of hepatitis C patients Amala Abdulla Saad Ahmed, Saneya Mohamed Rizk, Nabila Abdel-Kader Abdeldaiem Egyptian Nursing Journal.2023; 20(2): 159. CrossRef
Another Step Toward Hepatitis C Elimination: An Economic Evaluation of an Irish National Birth Cohort Testing Program Paul G. Carty, Conor Teljeur, Cillian F. De Gascun, Paddy Gillespie, Patricia Harrington, Aiden McCormick, Michelle O’Neill, Susan M. Smith, Mairin Ryan Value in Health.2022; 25(12): 1947. CrossRef
Oncogenic viruses, cancer biology, and innate immunity Maria C White, Xinjun Wu, Blossom Damania Current Opinion in Immunology.2022; 78: 102253. CrossRef