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Original Articles
- A study on Performing Time of Neurobehavioral Test in Workers exposed to Organic Solvents.
- Kang Won Park, In Geun Park, Jin Ha Kim, Kang Woo Bae, Duk Hee Lee, Yong Hawn Lee
- Korean J Prev Med. 1997;30(1):171-180.
- 2,146 View
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Abstract
PDF - This study was performed to see whether neurobehavioral tests was affected by the exposure-free time in the workers chronically exposed to organic solvents. Thirty-four female workers were participated and four items among neurobehavioral core test battery of World Health Organization, including digit span, Santa Ana Dexterity, digit symbol, Benton Visual Retention, were administered to the workers. Test was conducted three times-preshift on Monday, preshift on Weekday and during shift on Weekday-per person and the interval of tests was 2 weeks. Digit span forward, Santa Ana Dexterity, digit symbol, and Benton Visual Retention showed significant decrements by performing time, especially during shift on Weekday versus preshift on Monday and preshift on Weekday. In addition, the score at preshift on Weekday was significantly lower than preshift on Monday, in preferred Santa Ana Dexterity and digit symbol. Generally, those who were exposed to high concentration, over 50 years and under 6 years of education showed marked decrease of score at during shift. So, it would be desirable that neurobehavioral test is conducted at preshift on Monday and items related to short term memory could be considerable to be done at preshift on Weekday.
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Summary
- Effects of Organic Solvents on Hearing in Video Tape Manufacturing Workers.
- Hae Ryeon Shin, Jong Young Lee, Kuk Hyeun Woo, Jin Seok Kim
- Korean J Prev Med. 1997;30(1):61-68.
- 1,901 View
- 21 Download
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Abstract
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- This study was performed to evaluate the effects on hearing of video tape manufacturing workers exposed to organic solvents. The experimental groups included solvents exposed group 51 and unexposed group 57 workers. All workers was examined air and bone conduction sensitivity by pure tone audiometer. The mean age of solvents exposed group was 34.1 and nonexposed group was 35.8. The mean duration of solvents exposed group was 7.3years. High frequency hearing loss prevalence of both groups was 23.5% in the group exposed to organic solvents and 17.5% in nonexposed group. There is no statistical significants in the prevalence of high frequency hearing loss. According to comparison of mean auditory threshold value by frequencies, on the air conduction test, right was statistically significant in the 250, 500, 1000, 2000, 4000Hz, except 8000Hz. Left 250, 500, 1000Hz was statistically significant. On the bone conduction test, left250, both 500, 1000, 2000, 4000Hz, except right 250Hz, was statistically significant difference. Generally, auditory sensitivity threshold of the exposed group was higher than the nonexposed group.
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Summary
- The Assessment of Acquired Dyschromatopsia among Organic-Solvents Exposed Workers.
- Mi Jung Kang, Su Hee Kang, Suk Kwon Suh, Dong Hoon Shin, Jong Young Lee
- Korean J Prev Med. 1996;29(3):529-538.
- 1,945 View
- 22 Download
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Abstract
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- We investigated the occurrence of color vision loss in 70 organic solvent mixtures exposed workers and in 47 controls. Color Vision was assessed with a color arrangement test designed to identify the defective color sense, the Han Double 15-Hue Test. The results of the test were no significant difference between exposed workers and controls in the proportion of subjects who committed one or two errors. Quantitative analysis, using color confusion index(CCI), showed no signifiant difference between exposed workers and controls. A significant linear correlation was present between age and CCI in both exposed workers(CCi=0.0056age + 0.94; r=0.23; p<0.05) and controls(CCI=0.0066age + 0.86; r=0.33; p<0.05). Qualitative analysis of the patterns on the hue circle showed that the prevalence of acquired dyschromatopsia was 21% in both and no significant difference. Multiple regression analyses showed that age was significantly related to color vision loss. These results did not provide evidence of a relationship between organic solvents exposure and incidence of color vision loss. In field studies for monitor the people at risk of the acquired color vision loss involving low-dose organic solvents exposed workers, both quantitative and qualitative information should be considered.
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Summary
- Neurobehavioral Changes according to Cumulative Exposure of Complex Organic Solvents.
- Duk Hee Lee, In Geun Park, Jin Ha Kim, Young Hawn Lee, Sung Gye Kang, Doo Hie Kim
- Korean J Prev Med. 1995;28(2):386-397.
- 1,851 View
- 21 Download
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Abstract
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- A cross sectional study was performed to evaluate the neurobehavioral effects of chronic exposure of complex organic solvents, using NCTB(Neurobehavioral Core Test Battery) recommended by WHO(World Health organization). Forty female shoe factory workers and twenty-two controls matched with age were participated. The tests were performed in the morning before start of work, to exclude the effects of acute exposure. Workers were exposed mainly to toluene, methyl ethyl ketone, n-hexane, cyclo-hexane, dichloroethylene, trichloroethylene, benzene, xylenes etc. The ranges of present solvent exposure of hygienic effect were 0.46~0.71 in the process using adhesives indirectly, and 1.83-2.39 in the process using it directly. We reclassified the subjects, according to cumulative exposure. It showed significantly poorer performances in high exposed group on Santa Ana Dexterity and Benton visual Retention, compared with control group. After controlling confounder, the significances were still remained. But, further cohort studies, having the information of personal exposure dose from entering a factory, are required to clarify the effects of chronic exposure of complex organic solvents in relation to dose and duration of exposure.
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Summary
- A study of succiny trialanine p-nitroanilide hydrolytic activity in workers exposed to organic solvents.
- Hae Ju Oh, Jae Hoon Roh
- Korean J Prev Med. 1993;26(1):74-85.
- 1,979 View
- 18 Download
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Abstract
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- To measure the serum succinyl trialanine p-nitroanilide hydrolytic activity as new index of liver function in workers exposed to organic solvents, this study conducted 114 workers in department of shoe-making of shoes factories. The results obtained from this study were as follows: 1. The mean values of serum GOT, GPT, gamma GT in whole workers were 22+/-12.32, 20+/-9.65, 28+/-21.35IU/l, respectively and the mean value of serum STN hydrolytic activity was 0.08 0.05. 2. The serum STN hydrolytic activity was significantly higher for male(p<0.05) and there was no difference among the groups of age. 3. There was no difference in the groups by working hours but significant difference in persons who worked over 3 years or were exposed to toluene over 100ppm(p<0.05). 4. The correlation of the exposed dose of toluene and serum GOT, GPT, gamma GT and serum STN hydrolytic activity were statistically significant(r=0.027-0.518). 5. The exposed dose of toluene was most explainable variable and statistically significant among the factors affecting serum STN hydrolytic activity(p<0.05).
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Summary
- Hematologic Findings and Urinarysis of Workers Exposed to Mixed Organic Solvents.
- K W Jeong, D H Kim, S H Ohm, S J Kim, J H Kim, S S Moon, J H Chun, Y W Kim
- Korean J Prev Med. 1991;24(3):314-337.
- 2,066 View
- 20 Download
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Abstract
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- To evaluate the effects on health by exposure to mixed organic solvents, the author analyzed some labortory findings of blood(hemoglobin, hematocrit, RBC, WBC, SGOT, SGPT) and urine(protein, blood, sugar) that were obtained from 722 workers (male: 446, female: 276) who worked in plywood, painting and shoes factories in Pusan area from January to December, 1990. The result were as follows; 1. The mean values of each hematologic finding were all within normal limit but there were significant differences at hematocrit, RBC, WBC, SGOT, in male and at WBC, SGPT in female at the comparison of the mean values and the distribution according to the normal criteria by type of work. 2. There were no differences in urinalysis (protein, blood, sugar) by type of work. 3. In stepwise multiple regression, analysis of hematologic findings on age, working duration and type of work, regression coefficients on age and type of work were relatively high in male and female subject, respectively. As a result of this study, it is considered that the measurement of WBC with morphology is significant in hematologic findings and instead of spot urine and urinstix, 24 hours urine and quantitative analysis is required in urinalysis in screening test for healthy status of workers who deal with the organic solvents.
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Summary
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