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Sang Rok Lee 1 Article
Effects of Personal Exposure to Nitrogen Dioxide on Peak Expiratory Flow in Asthmatic Patients.
Ho Jang Kwon, Sang Gyu Lee, Young Koo Jee, Sang Rok Lee, Seung Sik Hwang
J Prev Med Public Health. 2007;40(1):59-63.
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AbstractAbstract PDF
Nitrogen dioxide (NO2) has been inconsistently associated with gradual decreases in lung function. Here, we studied the effects of NO2 exposure in asthmatics by examining the association between changes in lung function and concentrations of NO2 which were personally measured. METHODS: Peak expiratory flow (PEF) and daily personal exposures to NO2 were recorded on 28 patients with asthma (confirmed by methacholine provocation test) over 4 weeks. We used generalized estimating equations to assess the relationship between personal NO2 exposure and PEF, adjusting for potential confounders such as age, gender, outdoor particulate matter, temperature, humidity, and exposure to environmental tobacco smoke. RESULTS: The personal NO2 exposures were higher than the corresponding ambient levels. The mean personal: ambient ratio for NO2 was 1.48. The personal NO2 exposures were not associated with the morning PEF, evening PEF, or the diurnal PEF variability. However, environmental tobacco smoke was negatively associated with both the morning and evening PEF. CONCLUSIONS: Among the asthmatic adults who participated in this study, we found no apparent impact of personal NO2 exposures on the peak expiratory flow.


Citations to this article as recorded by  
  • The statistical evaluation and comparison of ADMS-Urban model for the prediction of nitrogen dioxide with air quality monitoring network
    Audrius Dėdelė, Auksė Miškinytė
    Environmental Monitoring and Assessment.2015;[Epub]     CrossRef
  • Acute effects of air pollution on peak expiratory flow rates and symptoms among asthmatic patients in Chiang Mai, Thailand
    Phongtape Wiwatanadate, Chalerm Liwsrisakun
    International Journal of Hygiene and Environmental Health.2011; 214(3): 251.     CrossRef

JPMPH : Journal of Preventive Medicine and Public Health