Associations of Non Alcoholic Fatty Liver with the Metabolic Syndrome and Serum Carotenoids.

Sun kyun Park; Hyun Jung Lee; Duk Hee Lee; Sung Kook Lee; Byung Yeol Chun; Sung Ae Kim; Hye Sung Lee; Hyo Kyung Son; Sung Hi Kim

doi:10.3961/jpmph.2008.41.1.39

Articles

Page Path: HOME > J Prev Med Public Health > Volume 41(1); 2008 > Article

English Abstract Associations of Non Alcoholic Fatty Liver with the Metabolic Syndrome and Serum Carotenoids.: Sun kyun Park, Hyun Jung Lee, Duk Hee Lee, Sung Kook Lee, Byung Yeol Chun, Sung Ae Kim, Hye Sung Lee, Hyo Kyung Son, Sung Hi Kim; Journal of Preventive Medicine and Public Health 2008;41(1):39-44
DOI: https://doi.org/10.3961/jpmph.2008.41.1.39

5,833 Views
69 Download
10 Crossref
8 Scopus

¹Department of Preventive Medicine, School of Medicine, Kyungpook National University, Korea. sunkyuney@hotmail.com
²Department of Food Science and Nutrition, Graduate School, Kyungpook National University, Korea.
³Health Promotion Research Center, Kyungpook National University, Korea.
⁴Department of Family Medicine, Daegu Catholic University Hospital, Korea.

prev next

Full Article

Download PDF

Abstract

OBJECTIVES
This study was conducted to investigate the associations of non alcoholic fatty liver with metabolic syndrome and the serum carotenoids. METHODS: This study was conducted in a general hospital in South Korea from November, 2004 to August, 2005. The study subjects were 350 sampled persons who were aged from 40 years and older (males: 180, females: 170). They were grouped into the normal, mild and severe groups according to fat accumulation in their livers, as determined by ultrasonography. We analyzed the association between non alcoholic fatty liver and metabolic syndrome by multiple logistic regression analysis and we analyzed the association between non alcoholic fatty liver and the serum carotenoids by a general linear model(ANCOVA). RESULTS: After adjustment for the effect of potential covariates, the prevalence of metabolic syndrome was associated with fat accumulation in the liver (p trend <0.001). If the odds ratio of normal group is 1.00, then that of the mild group is 2.80 (95% C.I=1.17-6.71) and that of the severe group is 7.29 (95% C.I=2.76-19.30). The prevalence of metabolic alterations fitting the criteria of metabolic syndrome, according to the class of fat accumulation in the liver, was significantly increased, except for criteria of high blood pressure, a large waist circumference and low HDL (high density lipoprotein) cholesterol level (p trend <0.001). The level of serum beta-carotene was decreased according to the class of fat accumulation in the liver (p trend=0.036), but the levels of serum alpha-carotene, lycopene, bata-cryptoxanthin and lutein were not decreased. CONCLSIONS: This study shows that non alcoholic fatty liver was associated with metabolic syndrome and with the serum beta-carotene level.

Keywords: Fatty liver;Metabolic syndrome X;Insulin resistance;Carotenoids;Obesity;Oxidative stress

Figure & Data

References

Citations

Citations to this article as recorded by

Estimation of Attributable Risk and Direct Medical and Non-Medical Costs of Major Mental Disorders Associated With Air Pollution Exposures Among Children and Adolescents in the Republic of Korea, 2011–2019
Yae Won Ha, Tae Hyun Kim, Dae Ryong Kang, Ki-Soo Park, Dong Chun Shin, Jaelim Cho, Changsoo Kim
Journal of Korean Medical Science.2024;[Epub] CrossRef
Therapeutic potential of bioactive phytoconstituents found in fruits in the treatment of non-alcoholic fatty liver disease: A comprehensive review
Manash Pratim Pathak, Kalyani Pathak, Riya Saikia, Urvashee Gogoi, Pompy Patowary, Pronobesh Chattopadhyay, Aparoop Das
Heliyon.2023; 9(4): e15347. CrossRef
The Protection Conferred by HSD17B13 rs72613567 Polymorphism on Risk of Steatohepatitis and Fibrosis May Be Limited to Selected Subgroups of Patients With NAFLD
Eduardo Vilar-Gomez, Carlos J. Pirola, Silvia Sookoian, Laura A. Wilson, Tiebing Liang, Naga Chalasani
Clinical and Translational Gastroenterology.2021; 12(9): e00400. CrossRef
Trends and Patterns of Burden of Disease and Injuries in Korea Using Disability-Adjusted Life Years
Young-Eun Kim, Hyesook Park, Min-Woo Jo, In-Hwan Oh, Dun-Sol Go, Jaehun Jung, Seok-Jun Yoon
Journal of Korean Medical Science.2019;[Epub] CrossRef
Dietary Carotenoids and Non-Alcoholic Fatty Liver Disease among US Adults, NHANES 2003–2014
Krista Christensen, Thomas Lawler, Julie Mares
Nutrients.2019; 11(5): 1101. CrossRef
Central obesity and nonalcoholic fatty liver disease risk after adjusting for body mass index
Qing Pang
World Journal of Gastroenterology.2015; 21(5): 1650. CrossRef
Association Between Liver Vitamin A Reserves and Severity of Nonalcoholic Fatty Liver Disease in the Class III Obese Following Bariatric Surgery
Gabriela Villaça Chaves, Sílvia Elaine Pereira, Carlos José Saboya, Daiane Spitz, Camila Santos Rodrigues, Andréa Ramalho
Obesity Surgery.2014; 24(2): 219. CrossRef
Association of oral health behaviors and status with depression: results from the Korean National Health and Nutrition Examination Survey, 2010
Se Jin Park, Ki Dong Ko, Seung-Il Shin, Yu Jeong Ha, Gy Young Kim, Hyoung Ah Kim
Journal of Public Health Dentistry.2014; 74(2): 127. CrossRef
Measuring the burden of chronic diseases in Korea in 2007
E.-J. Kim, S.-J. Yoon, M.-W. Jo, H.-J. Kim
Public Health.2013; 127(9): 806. CrossRef
The Association of Cardiovascular Risk Factors with Nonalcoholic Fatty Liver Disease in Health Checkup Examinees
Jae-Hee Yu, Kang-Sook Lee, Seon-Young Lee, A-Rum Hong, Yong-Sang Park
Journal of Preventive Medicine and Public Health.2008; 41(6): 407. CrossRef

Cite

Related articles