KSPM
Search
- Page Path
- HOME > Search
Original Articles
- Incidence Density of Antibody against Hepatitis C Virus in Seoul and Gyeonggi Area; A Retrospective Cohort Study: Based on Medical Screening Data from a General Hospital.
- Seung Ho Ryu, Dong Il Kim, Byung Seong Suh, Woon Sool Kim, Yoo Soo Chang, Sung Ho Beck, Soo Jin Lee, Jaechul Song, Yong Kyu Kim
- J Prev Med Public Health. 2004;37(4):337-344. Published online November 30, 2004
- 2,348 View
- 28 Download
-
Abstract
PDF - OBJECTIVES
This study was performed to determine the incidence density and the prevalence of sero-positive hepatitis C from 1999 to 2002 among adults aged 20 and over residing in Seoul and the Gyeonggi province. METHOD: The data for period was obtained from 114, 635 adults, residing in Seoul or the Gyeonggi province, who had undertaken comprehensive health screening tests from Jan 1999 to Dec 2002 in a University hospital in Seoul. Among them, subjects with sero-negative status against hepatitis C were selected (21, 408 in 1999, 28, 830 in 2000) and then followed up until Dec 2002 to determine the incidence of hepatitis C during this period. The serum was tested with the immunoradiometric assay (IRMA) which uses third generation HCV antibody. Age adjusted rates were estimated by direct standardization using a reference population of 2000 aged from 20 to 80 years. RESULTS: The prevalence of anti-HCV from 1999 to 2002 was 2.1 per 1000 persons (95% CI 1.8~2.4). Male showed 1.7 per 1000 persons (95% CI 1.4~2.1), while female showed 2.7 per 1000 persons (95% CI 2.2~3.2). Age?sex adjusted rate showed 2.8 per 1000 persons (95% CI 2.64~2.96), which is lower than the results of some previous study. The prevalence showed a significantly increasing pattern with age both in males and females (p< 0.05). The incidence density of anti-HCV among the population aged 20 and over was 1.1 per 104 person-years at risk (95% CI 0.6~2.4) ; 1.2 (95% CI 0.6~2.7) for males and 0.8 (95% CI 0.6~4.2) for females. Age adjusted incidence density was 2.91 per 104 person-years at risk (95% CI 2.43~3.38) for those aged 20 and over. It showed an increasing pattern with age (p< 0.05), especially for those age over 50 years. CONCLUSION: The study subjects for this study were supposedly healthier than the general population so the prevalence and incidence for the general population are thought to be higher than the results of the present study. -
Summary
- A Study on Serum Zinc Concentration in some Methamphetamine Abusers.
- Hyung Il Moon, Hoo Rak Lee, Soo Il Lee
- Korean J Prev Med. 1992;25(2):172-179.
- 2,030 View
- 20 Download
-
Abstract
PDF
- The author investigated the zinc concentrations in sera of 110 methamphetaimine abusers (male 87, female 23) and of 41 healthy official workers(male 29, female 12) using inductively coupled plasma emission spectrometer. The serum zinc concentrations were analysed according to hepatitis C virus antibody(Anti HCV), hepatitis B surface antigen(HBsAg) and alanine aminotransferase (ALT) value in both groups. The analytical results were obtained as follows; 1. The mean zinc concentration of MAP abuser group(298.5+/-246.9 microgram/100 microliter) was 2.5 times higher than that of control group(118.8+/-25.4 microgram/100 microliter). 2. The distribution of zinc concentration in both groups were skewed pattern. 3. The zinc concentration were higher in Anti HCV-positive group and abnormal ALT value group than Anti HCV-negative group and normal ALT value group. But HBs-Ag positive group had lower zinc concentration than HBs-Ag negative group. 4. The number of anti HCV-positive subjects was increased and the zinc concentration were decreased in proportion to the abusing duration of MAP.
-
Summary
- Seroprevalence of antibody to the hepatitis C virus in methamphetamine abusers.
- Jin Kyoo Kim, Ji Ho Lee, Byung Mann Cho, Soo Il Lee
- Korean J Prev Med. 1991;24(4):465-472.
- 1,896 View
- 21 Download
-
Abstract
PDF
- This study was designed to estimate the prevalence of hepatitis C virus(HCV) infection in drug abusers. The subjects were 141 inpatients who had been admitted to a general hospital with the symptoms and signs of methamphetamine intoxication. Seroprevalence of antibody to the hepatitis C virus(anti-HCV) was 60.3%,(85/141) and it was higher in the group with increased frequency and duration of drug abuse, but such a relationship was not found in the seroprevalence of hepatitis B surface antigen(HBsAg). These findings suggested the possibility of high prevalence of HCV infection in methamphetamine abusers, and the importance of repetitive percutaneous injection in the transmission of HCV infection.
-
Summary
First
Prev
