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English Abstract
- High Throughput Genotyping for Genomic Cohort Study.
- Woong Yang Park
- J Prev Med Public Health. 2007;40(2):102-107.
- DOI: https://doi.org/10.3961/jpmph.2007.40.2.102
- 4,524 View
- 25 Download
- 2 Crossref
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Abstract
PDF - Human Genome Project (HGP) could unveil the secrets of human being by a long script of genetic codes, which enabled us to get access to mine the cause of diseases more efficiently. Two wheels for HGP, bioinformatics and high throughput technology are essential techniques for the genomic medicine. While microarray platforms are still evolving, we can screen more than 500,000 genotypes at once. Even we can sequence the whole genome of an organism within a day. Because the future medicne will focus on the genetic susceptibility of individuals, we need to find genetic variations of each person by efficient genotyping methods.
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- A novel protein chip for simultaneous detection of antibodies against four epidemic swine viruses in China
Yue Wu, Xudan Wu, Jing Chen, Jingfei Hu, Xiaobo Huang, Bin Zhou
BMC Veterinary Research.2020;[Epub] CrossRef - Detection and Differentiation of Four Poultry Diseases Using Asymmetric Reverse Transcription Polymerase Chain Reaction in Combination with Oligonucleotide Microarrays
Qimeng Tao, Xiurong Wang, Hongmei Bao, Jianan Wu, Lin Shi, Yanbing Li, Chuanling Qiao, Samuilenko Anatolij Yakovlevich, Poukhova Nina Mikhaylovna, Hualan Chen
Journal of Veterinary Diagnostic Investigation.2009; 21(5): 623. CrossRef
Original Article- Specimen Storage and Analysis for Genomic Epidemiology.
- Yun Chul Hong, Kwan Hee Lee
- Korean J Prev Med. 2003;36(3):209-212.
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- Because of advances of technologies in the field of genomic epidemiology in the recent years, specimen collection, storage and analysis became an essential part of research methodologies. DNA is now being used in epidemiologic studies to evaluate genetic risk factors and specimens other than the fresh whole blood can be used for PCR. Therefore, All nucleated cells, such as buccal swabs and urine specimens, are suitable for DNA analysis. For an unlimited source of genomic DNA, EBV transformation of lymphocytes can be used for immortalization. However, the type of specimen collected in genomic epidemiologic studies will depend on the study where the epidemiologist play a leading role for the design. We also briefly described various kinds of analysis for SNP that is an essential part of the genomic epidemiology.
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