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Original Articles
The Diabetogenic Effect of Statin Use May Interact With Polygenic Risk Scores for Type 2 Diabetes: Evidence From the UK Biobank
Jong Hyun Park, Kyu-Taek Lim, Jooyeon Lee, Yongjin Gil, Joohon Sung
J Prev Med Public Health. 2025;58(1):92-102.   Published online December 11, 2024
DOI: https://doi.org/10.3961/jpmph.24.671
  • 1,340 View
  • 214 Download
AbstractAbstract AbstractSummary PDFSupplementary Material
Objectives
Statins are essential in the prevention of cardiovascular disease; however, their association with type 2 diabetes mellitus (T2DM) risk is concerning. We examined whether genetic susceptibility to T2DM modifies the association between regular statin use and T2DM risk.
Methods
This study included 447 176 individuals from the UK Biobank without baseline diabetes or major cardiovascular disease. Statin use was recorded at baseline, and T2DM incidence was determined using clinical records. Polygenic risk scores (PRS) for T2DM risk were provided by the UK Biobank. Using propensity scores adjusted for age, sex, body mass index, and comorbidities, 14 831 statin users were matched with 37 060 non-users. Cox proportional hazards models were used to estimate the interaction effect of statin use and PRS on T2DM incidence, adjusting for key confounders.
Results
In the propensity-matched cohort, 3675 of 51 891 participants developed T2DM over a mean follow-up period of 13.7 years. Within the top 5% of the PRS distribution, per 1000 person-years, the incidence of T2DM was 15.42 for statin users versus 12.18 for non-users. Among the lowest 5%, the incidence was 1.90 for statin users and 1.65 for non-users. Based on the Cox proportional hazards model, regular statin use was associated with a 1.24-fold increased T2DM risk (95% confidence interval [CI], 1.15 to 1.33). Furthermore, PRS exhibited a significant multiplicative interaction with regular statin use (odds ratio, 1.10; 95% CI, 1.02 to 1.19).
Conclusions
PRS may help identify individuals particularly susceptible to the diabetogenic effects of statins, providing a potential path for personalized cardiovascular disease management.
Summary
Korean summary
스타틴은 심혈관 질환 예방에 필수적이지만, 제2형 당뇨병 발생 위험을 높인다고 알려져 있습니다. 본 연구는 영국 바이오뱅크 데이터를 활용하여, 스타틴 사용과 제2형 당뇨병 다유전자 위험 점수(Polygenic Risk Score, PRS)의 상호작용이 당뇨병 발생 위험에 미치는 영향을 분석했습니다. 연구 결과, PRS가 높은 집단에서는 스타틴 사용이 제2형 당뇨병 발생 위험을 유의하게 증가시켰으나, PRS가 낮은 집단에서는 스타틴 사용이 오히려 당뇨병 위험을 낮추는 경향을 보였습니다. 이러한 결과는 유전적 요인을 고려한 맞춤형 심혈관 질환 예방 전략의 중요성을 시사합니다.
Key Message
This study highlights that the diabetogenic effect of statins interacts significantly with genetic predisposition, as quantified by polygenic risk scores (PRS) for type 2 diabetes mellitus (T2DM). Individuals with high PRS are at a significantly increased risk of developing T2DM with statin use, while those with low PRS may experience a reduced risk. These findings underscore the potential of integrating genetic risk stratification into clinical decision-making to optimize the balance between cardiovascular benefits and T2DM risk in statin therapy.
The Impact of Student-led Community Health Screenings on Clients’ Health Knowledge and Outcomes: A Qualitative Study in New Zealand
JiaRong Yap, Wendy Wenming Zhai, Cindy Seunghee Pak, Sharon Brownie
J Prev Med Public Health. 2025;58(2):167-176.   Published online November 28, 2024
DOI: https://doi.org/10.3961/jpmph.24.366
  • 773 View
  • 123 Download
AbstractAbstract AbstractSummary PDF
Objectives
This study investigated the impact of community health screenings (CHS) on the Asian community, focussing on the role of a student-led health and wellness centre in promoting and improving health outcomes. The CHS is a collaboration between Te Kotahi Oranga | Health and Wellness Centre and The Asian Network Incorporated, offering free health screenings to Asian migrants in the Waikato region, New Zealand.
Methods
Employing a qualitative approach, we interviewed clients who participated in the CHS to determine their perceptions regarding the effectiveness of the programme, its influence on their health knowledge and actions, and their overall satisfaction with the service. The Consolidated Criteria for Reporting Qualitative Research (COREQ) checklist was used to report the study.
Results
Data analysis utilising reflexive thematic analysis yielded 5 themes: satisfaction and appreciation for the free health screening; strengthened commitment to better personal health; barriers and challenges in accessing public healthcare services; improved knowledge and awareness of health risks; and provision of more health screening tests and health seminars. The findings highlight the significance of culturally tailored health initiatives in addressing healthcare disparities, emphasising the need for innovative strategies to ensure continuity of care and support for underserved populations.
Conclusions
This research contributes to the understanding of how student-led health interventions can enhance public health efforts and improve health outcomes in Asian and migrant communities.
Summary
Key Message
This study explores the impact of a student-led community health screening (CHS) programme on Asian migrants in New Zealand, focusing on its effects on health knowledge and outcomes. Through qualitative interviews, five key themes emerged: participant satisfaction, commitment to personal health, barriers to healthcare access, increased awareness of health risks, and the need for expanded screening services. The findings underscore the value of culturally tailored health initiatives in reducing healthcare disparities and highlight the role of student-led interventions in enhancing preventative care and promoting health equity in underserved populations.
Scoping Review
Is Farming a Risk Occupation for Cardio-cerebrovascular Diseases? A Scoping Review on Cardio-cerebrovascular Disease Risk in Farmers
Hyeonjun Kim, Wongeon Jung, Sunjin Jung, Seunghyeon Cho, Inho Jung, Hansoo Song, Ki-Soo Park, Seong-Yong Yoon, Joo Hyun Sung, Seok-Ju Yoo, Won-Ju Park
J Prev Med Public Health. 2024;57(6):521-529.   Published online August 23, 2024
DOI: https://doi.org/10.3961/jpmph.24.302
  • 1,691 View
  • 214 Download
  • 1 Web of Science
  • 1 Crossref
AbstractAbstract AbstractSummary PDFSupplementary Material
Objectives
In Korea, cardio-cerebrovascular disease (CCVD) is recognized as an occupational disease when sufficient evidence of a work-related burden exists. In 2021, approximately 26.8% of the payments from occupational disease insurance under the Industrial Accident Compensation Insurance Act were allocated to CCVDs. However, due to the specific nature of insurance policies for farmers, CCVD is not acknowledged as an occupational disease in their case.
Methods
We reviewed studies on the differences in the incidence, prevalence, and mortality rates of CCVDs between farmers and the general population or other occupations and described the exposure of farmers to risk factors for CCVDs.
Results
Several studies showed that farming is a high-risk occupation for CCVDs, with the following risk factors: long working hours, night work, lack of holidays, and strenuous physical labor; physical factors (noise, cold, heat, humidity, and vibration); exposure to hazardous gases (diesel exhaust, carbon monoxide, hydrogen sulfide, carbon disulfide, nitrogen oxides, and polycyclic aromatic hydrocarbons), pesticides, and dust (particulate matter, silica, and organic dust); exposure to a hypoxic environment; and job-related stress. Social isolation and lack of accessible medical facilities also function as additional risk factors by preventing farmers from receiving early interventions.
Conclusions
Farmers are exposed to various risk factors for CCVDs and are an occupation at risk for CCVDs. More studies are needed in the future to elucidate this relationship. This study lays the groundwork for future research to develop guidelines for approving CCVDs as occupational diseases among farmers.
Summary
Korean summary
이 연구는 농업이 뇌심혈관질환과 연관된 고위험 직업임을 입증하는 근거를 검토하였습니다. 농업인은 긴 근무 시간, 격렬한 신체 노동, 유해 가스 및 살충제 노출 등 다양한 위험 요인과 더불어 의료 접근성 부족과 같은 문제에 직면해 있습니다. 이는 뇌심혈관질환을 농업인의 업무 관련 질병으로 인정하기 위한 가이드라인 개발에 중요한 기초를 제공합니다.
Key Message
This study reviewed evidence supporting that farming is a high-risk occupation associated with cardio-cerebrovascular diseases. Farmers face various risk factors, including long working hours, strenuous physical labor, exposure to hazardous gases and pesticides, and challenges such as limited access to medical care. This provides an essential foundation for developing guidelines to recognize cardio-cerebrovascular diseases as work-related illnesses among farmers.

Citations

Citations to this article as recorded by  
  • Leveraging Administrative Health Databases to Address Health Challenges in Farming Populations: Scoping Review and Bibliometric Analysis (1975-2024)
    Pascal Petit, Nicolas Vuillerme
    JMIR Public Health and Surveillance.2025; 11: e62939.     CrossRef
Original Article
Workstation Risk Factors for Work-related Musculoskeletal Disorders Among IT Professionals in Indonesia
Tofan Agung Eka Prasetya, Nurul Izzah Abdul Samad, Aisy Rahmania, Dian Afif Arifah, Ratih Andhika Akbar Rahma, Abdullah Al Mamun
J Prev Med Public Health. 2024;57(5):451-460.   Published online July 25, 2024
DOI: https://doi.org/10.3961/jpmph.24.214
  • 3,391 View
  • 364 Download
AbstractAbstract AbstractSummary PDF
Objectives
This study aimed to identify workstation factors influencing work-related musculoskeletal disorders (WMSDs) among information technology (IT) professionals in Indonesia.
Methods
A cross-sectional study was conducted among 150 IT workers at small-enterprise companies who were randomly selected across East Java, Indonesia. The data were modeled using multiple linear regression, with a 95% level of confidence for determining statistical significance.
Results
The respondents reported that the neck had the highest level of discomfort and was the most at risk of WMSDs, followed by the lower back, right shoulder, and upper back. Screen use duration (p=0.040) was associated with whole-body WMSDs, along with seat width (p=0.059), armrest (p=0.027), monitor (p=0.046), and a combined telephone and monitor score (p=0.028). Meanwhile, the factors significantly related to the risk of WMSDs in the hands and wrist were working period (p=0.039), night shift (p=0.024), backrest (p=0.008), and mouse score (p=0.032).
Conclusions
Occupational safety authorities, standards-setting departments, and policymakers should prioritize addressing the risk factors for WMSDs among IT professionals.
Summary
Key Message
This study investigates workstation risk factors contributing to work-related musculoskeletal disorders (WMSDs) among IT professionals in Indonesia. Findings indicate that neck discomfort is the most prevalent, with significant associations identified between WMSDs and factors such as screen use duration, seating arrangements, and work conditions. The results underscore the need for ergonomic improvements and targeted preventive measures to enhance occupational health and safety for IT workers.
Systematic Review
Adjusting for Confounders in Outcome Studies Using the Korea National Health Insurance Claim Database: A Review of Methods and Applications
Seung Jin Han, Kyoung Hoon Kim
J Prev Med Public Health. 2024;57(1):1-7.   Published online November 16, 2023
DOI: https://doi.org/10.3961/jpmph.23.250
  • 3,556 View
  • 477 Download
  • 6 Web of Science
  • 6 Crossref
AbstractAbstract AbstractSummary PDF
Objectives
Adjusting for potential confounders is crucial for producing valuable evidence in outcome studies. Although numerous studies have been published using the Korea National Health Insurance Claim Database, no study has critically reviewed the methods used to adjust for confounders. This study aimed to review these studies and suggest methods and applications to adjust for confounders.
Methods
We conducted a literature search of electronic databases, including PubMed and Embase, from January 1, 2021 to December 31, 2022. In total, 278 studies were retrieved. Eligibility criteria were published in English and outcome studies. A literature search and article screening were independently performed by 2 authors and finally, 173 of 278 studies were included.
Results
Thirty-nine studies used matching at the study design stage, and 171 adjusted for confounders using regression analysis or propensity scores at the analysis stage. Of these, 125 conducted regression analyses based on the study questions. Propensity score matching was the most common method involving propensity scores. A total of 171 studies included age and/or sex as confounders. Comorbidities and healthcare utilization, including medications and procedures, were used as confounders in 146 and 82 studies, respectively.
Conclusions
This is the first review to address the methods and applications used to adjust for confounders in recently published studies. Our results indicate that all studies adjusted for confounders with appropriate study designs and statistical methodologies; however, a thorough understanding and careful application of confounding variables are required to avoid erroneous results.
Summary
Korean summary
건강보험청구자료를 사용한 성과연구에서는 교란요인 통제가 중요하다. 최근 발표된 연구들은 연구설계와 통계 분석 과정에 적절하게 교란요인을 통제하였다. 연구의 질을 높이기 위해서는 건강보험청구자료에서 수집 가능한 교란 요인에 대한 이해와 방법론적 가이드라인이 요구된다.
Key Message
All recently published studies using Health Insurance Claims Database adjusted for confounders with appropriate study designs and statistical methodologies. The review suggests the need for careful application of confounding variables and the methodological guidance to improve the quality of outcome studies.

Citations

Citations to this article as recorded by  
  • Factors Associated With Receiving Early Post-Discharge Follow-up Care in Patients With Schizophrenia
    Song Ee Che, Kyoung-Hoon Kim
    Journal of Korean Medical Science.2025;[Epub]     CrossRef
  • The Diabetogenic Effect of Statin Use May Interact With Polygenic Risk Scores for Type 2 Diabetes: Evidence From the UK Biobank
    Jong Hyun Park, Kyu-Taek Lim, Jooyeon Lee, Yongjin Gil, Joohon Sung
    Journal of Preventive Medicine and Public Health.2025; 58(1): 92.     CrossRef
  • Worsening of health disparities across COVID-19 pandemic stages in Korea
    Hyejin Lee, Hyunwoo Nam, Jae-ryun Lee, Hyemin Jung, Jin Yong Lee
    Epidemiology and Health.2024; 46: e2024038.     CrossRef
  • Trends in Regional Disparities in Cardiovascular Surgery and Mortality in Korea: A National Cross-sectional Study
    Dal-Lae Jin, Kyoung-Hoon Kim, Euy Suk Chung, Seok-Jun Yoon
    Journal of Preventive Medicine and Public Health.2024; 57(3): 260.     CrossRef
  • Low household income increases risks for chronic obstructive pulmonary disease in young population: a nationwide retrospective cohort study in South Korea
    Chiwook Chung, Kyu Na Lee, Dong Wook Shin, Sei Won Lee, Kyungdo Han
    BMJ Open Respiratory Research.2024; 11(1): e002444.     CrossRef
  • An epidemic of cataract surgery in Korea: the effects of private health insurance on the National Health Insurance Service
    Hyejin Lee, Soo-Hee Hwang, Choon-Seon Park, Seol-Hee Chung, Catherine L. Chen, Jin Yong Lee, Jin Soo Lee
    Epidemiology and Health.2024; 46: e2024015.     CrossRef
Perspective
A Lifestyle Communication Tool: Association of E-cigarette Use and Pre-diabetes
Nilanga Aki Bandara, Tanisha Vallani, Xuan Randy Zhou, Senara Hansini Palihawadane, Rochelle Gamage, Miles Mannas, Jay Herath
J Prev Med Public Health. 2023;56(4):384-387.   Published online July 31, 2023
DOI: https://doi.org/10.3961/jpmph.23.086
  • 2,697 View
  • 110 Download
AbstractAbstract PDF
The aim of this study was to present a framework for clinicians to use when discussing electronic cigarette (e-cigarette) use and its association with pre-diabetes. A communication tool was designed using evidence-based strategies from the academic literature. A four-step framework is presented, which includes: step (1) helping patients to understand the association between e-cigarette use and pre-diabetes; step (2) the synergistic health impacts of e-cigarette use and pre-diabetes; step (3) management of diabetes-related lifestyle factors; and step (4) stages of change assessment related to e-cigarette reduction. This communication tool provides support for clinicians to discuss the risk of pre-diabetes associated with e-cigarette use. Moving forward, implementation and evaluation of this model are needed.
Summary
Special Article
Examining the Role of Psychosocial Stressors in Hypertension
Komal Marwaha
J Prev Med Public Health. 2022;55(6):499-505.   Published online November 30, 2022
DOI: https://doi.org/10.3961/jpmph.21.266
  • 10,588 View
  • 353 Download
  • 11 Crossref
AbstractAbstract PDF
Despite advances in medicine and preventive strategies, fewer than 1 in 5 people with hypertension have the problem under control. This could partly be due to gaps in fully elucidating the etiology of hypertension. Genetics and conventional lifestyle risk factors, such as the lack of exercise, unhealthy diet, excess salt intake, and alcohol consumption, do not fully explain the pathogenesis of hypertension. Thus, it is necessary to revisit other suggested risk factors that have not been paid due attention. One such factor is psychosocial stress. This paper explores the evidence for the association of psychosocial stressors with hypertension and shows that robust evidence supports the role of a chronic stressful environment at work or in marriage, low socioeconomic status, lack of social support, depression, anxiety, post-traumatic stress, childhood psychological trauma, and racial discrimination in the development or progression of hypertension. Furthermore, the potential pathophysiological mechanisms that link psychosocial stress to hypertension are explained to address the ambiguity in this area and set the stage for further research.
Summary

Citations

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  • Exploring the complex relationship between psychosocial stress and the gut microbiome: implications for inflammation and immune modulation
    Komal Marwaha, Ryan Cain, Katherine Asmis, Katya Czaplinski, Nathan Holland, Darly C. Ghislaine Mayer, Jessica Chacon
    Journal of Applied Physiology.2025; 138(2): 518.     CrossRef
  • Anxiety and hypertension in young and middle-aged adults: a longitudinal cohort study
    Leah Jones, Jamie L Romeiser
    Journal of Public Health.2025;[Epub]     CrossRef
  • Masked hypertension in irritable bowel syndrome: A cause for concern?
    Gurpreet Singh Wander, Akash Batta
    Indian Journal of Gastroenterology.2025;[Epub]     CrossRef
  • Lifestyle Factors, Sociodemographic Characteristics and Incident Hypertension: A Prospective Analysis of the Korean National Health Insurance Service Sample Cohort
    Jung-Eun Lee, Anthony Kityo, Sang-Ah Lee
    Journal of Personalized Medicine.2024; 14(9): 959.     CrossRef
  • Psychological stress among hypertensive male patients in Jordan: prevalence and associated factors
    Ali Aldirawi, Fadwa Alhalaiqa, Abdallah Alwawi, Samer Abuzerr
    BMC Public Health.2024;[Epub]     CrossRef
  • Health-related factors and dysregulation of epigenetic related genes in metabolic syndrome trigger finger patients and smoker trigger finger patients: preliminary analysis of patient-derived sample
    Abdulaziz M. F. Shayea, Amna A. Alshatti, Danah H. Alfadhli, Almutairi Fatimah Ibrahim, Mariam Kh. Almutairi, Mohammed Sh. Nadar
    Journal of Orthopaedic Surgery and Research.2023;[Epub]     CrossRef
  • Adjustment disorders, hypertension and type 2 diabetes: a cardiologist’s view (literature review)
    D.K. Miloslavsky, S.M. Koval
    INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine).2023; 19(5): 383.     CrossRef
  • Letter to the Editor: Insights on Health, Religion/Spirituality, and Vulnerable Populations
    Fides A. del Castillo
    Journal of Preventive Medicine and Public Health.2023; 56(1): 97.     CrossRef
  • Moderating effect of mindfulness on the relationship between anxiety and somatization symptoms in middle‐aged and elderly female patients with hypertension
    Haifei Shen, Ri Zhang, XiuJie Zhang, Ying Zhang, Yan Liu, Wei Song, Yunpeng Cheng, Minghui Yang, Yinong Jiang, Yan Lu
    The Journal of Clinical Hypertension.2023; 25(7): 647.     CrossRef
  • Investigating the Mediating Role of Attachment Styles in the Relationship between Perceived Stress and Hypertension
    M Molaei, F Shahabizadeh
    Journal of Health and Care.2023; 25(2): 135.     CrossRef
  • Exploring the health of child protection workers: A call to action
    Javier F. Boyas, Debra Moore, Maritza Y. Duran, Jacqueline Fuentes, Jana Woodiwiss, Leah McCoy, Antonella Cirino
    Health Promotion Perspectives.2022; 12(4): 381.     CrossRef
Original Article
Effects of Marital Status and Income on Hypertension: The Korean Genome and Epidemiology Study (KoGES)
Mia Son, Yeon Jeong Heo, Hye-Jin Hyun, Ho Jong Kwak
J Prev Med Public Health. 2022;55(6):506-519.   Published online October 7, 2022
DOI: https://doi.org/10.3961/jpmph.22.264
  • 8,544 View
  • 272 Download
  • 8 Web of Science
  • 7 Crossref
AbstractAbstract AbstractSummary PDF
Objectives
This study aimed to analyze the associations of income, marital status, and health behaviors with hypertension in male and female over 40 years of age in the Korea.
Methods
The data were derived from the Korean Genome and Epidemiology Study (KoGES; 4851-302) which included 211 576 participants. To analyze the relationships of income, marital status, and health behaviors with hypertension in male and female over 40 years of age, multiple logistic regression was conducted with adjustments for these variables.
Results
The prevalence of hypertension increased linearly as income decreased. The odds ratio for developing hypertension in people with an income of <0.5 million Korean won (KRW) compared to ≥6.0 million KRW was 1.55 (95% confidence interval [CI], 1.25 to 1.93) in the total population, 1.58 (95% CI, 1.27 to 1.98) in male, and 1.07 (95% CI, 0.35 to 3.28) in female. The combined effect of income level and marital status on hypertension was significant. According to income level and marital status, in male, low income and divorce were most associated with hypertension (1.76 times; 95% CI, 1.01 to 3.08). However, in female, the low-income, married group was most associated with hypertension (1.83 times; 95% CI, 1.71 to 1.97).
Conclusions
The results of this study show that it is necessary to approach male and female marital status separately according to income in health policies to address inequalities in the prevalence of hypertension.
Summary
Korean summary
이 연구는 한국의 40세 이상 성인 남녀를 대상으로 소득수준, 결혼, 건강행태요인이 고혈압에 미치는 영향을 분석하였다. 이 연구는 한국인유전체역학조사사업조사(KoGES; 4851-302, 2001-2011)에서 구축한 211576명을 대상으로 다중 로지스틱회귀모델을 이용하여 분석했다. 소득이 고혈압에 미치는 영향은 역의 선형으로 소득이 적을수록 고혈압이 증가하는 경향이 뚜렷하게 나타났다. 소득수준과 혼인상태, 고혈압과의 연관성은 여성보다 남성이 더 강하게 나타났다. 소득수준과 혼인상태가 상호작용하여 고혈압에 미치는 영향에서, 저소득층에서 별거 상태가 고혈압에 미치는 전반적인 영향이 가장 강하게 나타났으며, 남성의 경우 이혼 상태, 여성의 경우 결혼을 유지하고 있는 상태가 고혈압과 가장 강하게 연관되어, 남녀사이에 차이가 존재함을 보여주었다. 이 연구는 소득, 결혼이 고혈압에 중요하게 영향을 미치는 것으로 나타나, 고혈압예방대책에 저소득과 별거 이혼등의 결혼상태를 고려하는것이 필요하다는 것을 제안한다.

Citations

Citations to this article as recorded by  
  • Marital status and risk of type 2 diabetes among middle-aged and elderly population: a systematic review and meta-analysis
    Mohammad Amin Karimi, Sara Binaei, Seyed Hadi Hashemi, Pegah Refahi, Ensiyeh Olama, Elnaz Olama, Aydin Mohammadpour, Reza Mostafaei Yonjali, Mohadeseh Poudineh, Niloofar Deravi
    Frontiers in Medicine.2025;[Epub]     CrossRef
  • Geo-behavioural predictors of diagnosed hypertension in Igbo Ora Area, Oyo State, Nigeria
    Olalekan J. Taiwo, Joshua O. Akinyemi, Ayodeji Adebayo, Oluwafemi A. Popoola, Rufus O. Akinyemi, Onoja M. Akpa, Paul Olowoyo, Akinkunmi P. Okekunle, Ezinne O. Uvere, Omotolani Titilayo Ajala, Chukwuemeka Nwimo, Olayinka J. Adebajo, Adewale E. Ayodele, Ayo
    BMC Public Health.2025;[Epub]     CrossRef
  • Interpersonal Factors Influencing Hypertension Control: A Cross‐Sectional Study Among Hypertensive Patients in the Ashanti Region, Ghana
    Francis Sambah, Kristin McBain‐Rigg, Abdul‐Aziz Seidu, Theophilus I. Emeto
    Health Science Reports.2025;[Epub]     CrossRef
  • The impact of retirement on blood pressure: evidence from a nationwide survey in China
    Jiarun Mi, Xueyan Han, Man Cao, Hanchao Cheng, Zhaoyang Pan, Jian Guo, Wei Sun, Yuanli Liu, Congyi Zheng, Xin Wang, Xue Cao, Zhen Hu, Yixin Tian, Zengwu Wang, Tianjia Guan
    BMC Public Health.2024;[Epub]     CrossRef
  • Knowledge, Attitude, and Practice of Stroke Among Hypertensive Patients in Selected Hospitals, Mogadishu: A Cross‐Sectional Study
    Walid Abdulkadir Osman, Hassan Muse Ahmed, Maryan Mukhtar Abdullahi, Amal Adam Kuule, Qaali Barre Hassan
    Health Science Reports.2024;[Epub]     CrossRef
  • Psychological stress among hypertensive male patients in Jordan: prevalence and associated factors
    Ali Aldirawi, Fadwa Alhalaiqa, Abdallah Alwawi, Samer Abuzerr
    BMC Public Health.2024;[Epub]     CrossRef
  • Shapely additive values can effectively visualize pertinent covariates in machine learning when predicting hypertension
    Alexander A. Huang, Samuel Y. Huang
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Systematic Review
Vitamin D Deficiency and Comorbidities as Risk Factors of COVID-19 Infection: A Systematic Review and Meta-analysis
Pinki Mishra, Rizwana Parveen, Ram Bajpai, Nidhi Agarwal
J Prev Med Public Health. 2022;55(4):321-333.   Published online June 13, 2022
DOI: https://doi.org/10.3961/jpmph.21.640
  • 6,989 View
  • 215 Download
  • 9 Web of Science
  • 12 Crossref
AbstractAbstract PDFSupplementary Material
Objectives
Extensive evidence links low vitamin D status and comorbidities with coronavirus disease 2019 (COVID-19) outcomes, but the results of published studies are contradictory. Therefore, we investigated the association of lower levels of vitamin D and comorbidities with the risk of COVID-19 infection.
Methods
We searched MEDLINE (via PubMed), Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov for articles published until August 20, 2021. Sixteen eligible studies were identified (386 631 patients, of whom 181 114 were male). We included observational cohort and case-control studies that evaluated serum levels of vitamin D in COVID-19-positive and COVID-19-negative patients. Mean differences (MDs) with 95% confidence intervals (CIs) were calculated.
Results
Significantly lower vitamin D levels were found in COVID-19-positive patients (MD, -1.70; 95% CI, -2.74 to -0.66; p=0.001), but with variation by study design (case-control: -4.04; 95% CI, -5.98 to -2.10; p<0.001; cohort: -0.39; 95% CI, -1.62 to 0.84; p=0.538). This relationship was more prominent in female patients (MD, -2.18; 95% CI, -4.08 to -0.28; p=0.024) than in male patients (MD, -1.74; 95% CI, -3.79 to 0.31; p=0.096). Male patients showed higher odds of having low vitamin D levels (odds ratio [OR], 2.09; 95% CI, 1.38 to 3.17; p<0.001) than female patients (OR, 1.17; 95% CI, 0.74 to 1.86; p=0.477). Comorbidities showed inconsistent, but generally non-significant, associations with COVID-19 infection.
Conclusions
Low serum vitamin-D levels were significantly associated with the risk of COVID-19 infection. This relationship was stronger in female than in male COVID-19 patients. Limited evidence was found for the relationships between comorbidities and COVID-19 infection, warranting large population-based studies to clarify these associations.
Summary

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  • Association Between Vitamin D and COVID-19–Related Outcomes: An Umbrella Review of Meta-Analyses
    Jia-ming Yang, Ze-qin Li, Yan-biao Zhong, Hui-yong Xie, Yun Luo, Li Xiao, Jing-hai Liao, Mao-yuan Wang
    Nutrition Reviews.2025;[Epub]     CrossRef
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    Carolina Teles, Ana Borges, Ana Magalhães, Cátia Barra, Isabel Silva, Patrícia Tomé, Jorge Crespo, Artur Paiva, Lèlita Santos
    Medicina Clínica.2025; 164(12): 106920.     CrossRef
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    V. V. Krivosheev, L. Yu. Nikitina, I. V. Kozlovskiy, A. V. Fedorov
    Sanitarnyj vrač (Sanitary Doctor).2024; (1): 27.     CrossRef
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    Nataliia Grygorieva, Mykola Tronko, Volodymir Kovalenko, Serhiy Komisarenko, Tetiana Tatarchuk, Ninel Dedukh, Mykola Veliky, Serhiy Strafun, Yulia Komisarenko, Andrii Kalashnikov, Valeria Orlenko, Volodymyr Pankiv, Oleg Shvets, Inna Gogunska, Svitlana Reg
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    Marharyta Sobczak, Rafał Pawliczak
    Nutrients.2024; 16(10): 1402.     CrossRef
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    R Bajpai
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    Petra Rust, Cem Ekmekcioglu
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Original Articles
Decomposition of Socioeconomic Inequality in Cardiovascular Disease Prevalence in the Adult Population: A Cohort-based Cross-sectional Study in Northwest Iran
Farhad Pourfarzi, Telma Zahirian Moghadam, Hamed Zandian
J Prev Med Public Health. 2022;55(3):297-306.   Published online May 3, 2022
DOI: https://doi.org/10.3961/jpmph.22.051
  • 5,011 View
  • 114 Download
  • 2 Web of Science
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AbstractAbstract PDFSupplementary Material
Objectives
The incidence of cardiovascular disease (CVD) mortality is increasing in developing countries. This study aimed to decompose the socioeconomic inequality of CVD in Iran.
Methods
This cross-sectional population-based study was conducted on 20 519 adults who enrolled in the Ardabil Non-Communicable Disease cohort study. Principal component analysis and multivariable logistic regression were used, respectively, to estimate socioeconomic status and to describe the relationships between CVD prevalence and the explanatory variables. The relative concentration index, concentration curve, and Blinder-Oaxaca decomposition model were used to measure and decompose the socioeconomic inequality.
Results
The overall age-adjusted prevalence of CVD was 8.4% in northwest Iran. Multivariable logistic regression showed that older adults, overweight or obese adults, and people with hypertension and diabetes were more likely to have CVD. Moreover, people with low economic status were 38% more likely to have CVD than people with high economic status. The prevalence of CVD was mainly concentrated among the poor (concentration index, -0.077: 95% confidence interval, -0.103 to -0.060), and 78.66% of the gap between the poorest and richest groups was attributed to differences in the distribution of the explanatory variables included in the model.
Conclusions
The most important factors affecting inequality in CVD were old age, chronic illness (hypertension and diabetes), marital status, and socioeconomic status. This study documented stark inequality in the prevalence of CVD, wherein the poor were more affected than the rich. Therefore, it is necessary to implement policies to monitor, screen, and control CVD in poor people living in northwest Iran.
Summary

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  • Impact of Social Determinants of Health on Cardiovascular Disease
    George Bazoukis, Joseph Loscalzo, Jennifer L. Hall, Sandeep Chandra Bollepalli, Jagmeet P. Singh, Antonis A. Armoundas
    Journal of the American Heart Association.2025;[Epub]     CrossRef
  • A Global Perspective on Socioeconomic Determinants of Cardiovascular Health
    Bart Wilder, Alejandro Pinedo, Salaheldin Abusin, David Ansell, Adrian Matias Bacong, James Calvin, Sung Whoy Cha, Rami Doukky, Faisal Hasan, Shengyuan Luo, Ahmet Afşin Oktay, Latha Palaniappan, Natasha Rana, Frederick Berro Rivera, Basmah Fayaz, Ahmed Al
    Canadian Journal of Cardiology.2024;[Epub]     CrossRef
Association Between Sleep Quality and Anxiety in Korean Adolescents
Hyunkyu Kim, Seung Hoon Kim, Sung-In Jang, Eun-Cheol Park
J Prev Med Public Health. 2022;55(2):173-181.   Published online February 10, 2022
DOI: https://doi.org/10.3961/jpmph.21.498
  • 7,496 View
  • 304 Download
  • 21 Web of Science
  • 28 Crossref
AbstractAbstract AbstractSummary PDF
Objectives
Anxiety disorder is among the most prevalent mental illnesses among adolescents. Early detection and proper treatment are important for preventing sequelae such as suicide and substance use disorder. Studies have suggested that sleep duration is associated with anxiety disorder in adolescents. In the present study, we investigated the association between sleep quality and anxiety in a nationally representative sample of Korean adolescents.
Methods
This cross-sectional study was conducted using data from the 2020 Korea Youth Risk Behavior Web-based Survey. The Generalized Anxiety Disorder-7 questionnaire was used to evaluate anxiety. The chi-square test was used to investigate and compare the general characteristics of the study population, and multiple logistic regression analysis was used to analyze the relationship between sleep quality and anxiety.
Results
In both sexes, anxiety was highly prevalent in participants with poor sleep quality (adjusted odds ratio [aOR], 1.56; 95% confidence interval [CI], 1.43 to 1.71 in boys; aOR, 1.30; 95% CI, 1.19 to 1.42 in girls). Regardless of sleep duration, participants with poor sleep quality showed a high aOR for anxiety.
Conclusions
This study identified a consistent relationship between sleep quality and anxiety in Korean adolescents regardless of sleep duration.
Summary
Korean summary
청소년건강행태조사를 이용하여 청소년들의 수면의 질과 불안과의 연관성을 분석하였다. 좋지 않은 수면의 질은 불안감과 연관성이 있었으며 이 연관성은 대상자들의 수면시간과 상관없이 나타났다.

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    Yonghwan Moon, Hyekyung Woo
    Frontiers in Public Health.2025;[Epub]     CrossRef
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    Sun-Hwa Kim, So-Yeon Ryu, Seong-Woo Choi, Mi-Ah Han, Jong Park
    Journal of Health Informatics and Statistics.2025; 50(1): 65.     CrossRef
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    Ya-Ting Wen, Kuan-Po Lien, Jerry Cheng-Yen Lai, Shaw-Ji Chen
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    Current Perspectives in Social Sciences.2025; 29(1): 100.     CrossRef
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    Fuzhi Liu, Dandan Zhu, Lifeng Deng, Yanyan Zhao, Yangjia Chen, Zhuote Tu, Ahmad Neyazi
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Factors Related to Regional Variation in the High-risk Drinking Rate in Korea: Using Quantile Regression
Eun Su Kim, Hae-Sung Nam
J Prev Med Public Health. 2021;54(2):145-152.   Published online March 16, 2021
DOI: https://doi.org/10.3961/jpmph.20.507
  • 4,875 View
  • 135 Download
  • 4 Web of Science
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AbstractAbstract AbstractSummary PDFSupplementary Material
Objectives
This study aimed to identify regional differences in the high-risk drinking rate among yearly alcohol users in Korea and to identify relevant regional factors for each quintile using quantile regression.
Methods
Data from 227 counties surveyed by the 2017 Korean Community Health Survey (KCHS) were analyzed. The analysis dataset included secondary data extracted from the Korean Statistical Information Service and data from the KCHS. To identify regional factors related to the high-risk drinking rate among yearly alcohol users, quantile regression was conducted by dividing the data into 10%, 30%, 50%, 70%, and 90% quantiles, and multiple linear regression was also performed.
Results
The current smoking rate, perceived stress rate, crude divorce rate, and financial independence rate, as well as one’s social network, were related to the high-risk drinking rate among yearly alcohol users. The quantile regression revealed that the perceived stress rate was related to all quantiles except for the 90% quantile, and the financial independence rate was related to the 50% to 90% quantiles. The crude divorce rate was related to the high-risk drinking rate among yearly alcohol users in all quantiles.
Conclusions
The findings of this study suggest that local health programs for high-risk drinking are needed in areas with high local stress and high crude divorce rates.
Summary
Korean summary
본 연구는 quantile regression을 이용하여 high risk drinking 의 지역간 변이 요인을 파악하였습니다. 연구결과, high risk drinking rate 의 지역간 변이가 크고, quanile별로 관련요인을 다르다는 것을 파악하였습니다. 본 연구의 결과는 높은 지역의 스트레스와 조이혼율의 관리와 함께 지역 고위험음주율의 건강프로그램이 필요하다는 것을 암시한다.

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Modeling Survival in Patients With Brain Stroke in the Presence of Competing Risks
Solmaz Norouzi, Mohammad Asghari Jafarabadi, Seyed Morteza Shamshirgaran, Farshid Farzipoor, Ramazan Fallah
J Prev Med Public Health. 2021;54(1):55-62.   Published online December 7, 2020
DOI: https://doi.org/10.3961/jpmph.20.463
  • 4,442 View
  • 139 Download
  • 1 Web of Science
  • 1 Crossref
AbstractAbstract PDF
Objectives
After heart disease, brain stroke (BS) is the second most common cause of death worldwide, underscoring the importance of understanding preventable and treatable risk factors for the outcomes of BS. This study aimed to model the survival of patients with BS in the presence of competing risks.
Methods
This longitudinal study was conducted on 332 patients with a definitive diagnosis of BS. Demographic characteristics and risk factors were collected by a validated checklist. Patients’ mortality status was investigated by telephone follow-up to identify deaths that may be have been caused by stroke or other factors (heart disease, diabetes, high cholesterol, etc.). Data were analyzed by the Lunn-McNeil approach at alpha=0.1.
Results
Older age at diagnosis (59-68 years: adjusted hazard ratio [aHR], 2.19; 90% confidence interval [CI], 1.38 to 3.48; 69-75 years: aHR, 5.04; 90% CI, 3.25 to 7.80; ≥76 years: aHR, 5.30; 90% CI, 3.40 to 8.44), having heart disease (aHR, 1.65; 90% CI, 1.23 to 2.23), oral contraceptive pill use (women only) (aHR, 0.44; 90% CI, 0.24 to 0.78) and ischemic stroke (aHR, 0.52; 90% CI, 0.36 to 0.74) were directly related to death from BS. Older age at diagnosis (59-68 years: aHR, 21.42; 90% CI, 3.52 to 130.39; 75-69 years: aHR, 16.48; 90% CI, 2.75 to 98.69; ≥76 years: aHR, 26.03; 90% CI, 4.06 to 166.93) and rural residence (aHR, 2.30; 90% CI, 1.15 to 4.60) were directly related to death from other causes. Significant risk factors were found for both causes of death.
Conclusions
BS-specific and non-BS-specific mortality had different risk factors. These findings could be utilized to prescribe optimal and specific treatment.
Summary

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  • Deep neural network base competing risk in predicting heart failure patient’s survival
    Solmaz Norouzi, Ebrahim Hajizadeh, Mohammad Asghari Jafarabadi, Nasim Naderi, Saeideh Mazloomzadeh
    Journal of Diabetes & Metabolic Disorders.2025;[Epub]     CrossRef
Association Between Parental Marital Status and Types of Suicidal Behavior Among Korean Adolescents: A Cross-sectional Study
Yoon Sik Park, Eun-Cheol Park
J Prev Med Public Health. 2020;53(6):419-428.   Published online September 21, 2020
DOI: https://doi.org/10.3961/jpmph.20.004
  • 5,308 View
  • 189 Download
  • 7 Crossref
AbstractAbstract PDF
Objectives
Adolescent suicide is a global problem. This study aimed to identify associations between parental marital status and suicidal behavior.
Methods
This study analyzed 118 715 middle and high school students from the 13th and 14th Korea Youth Risk Behavior Web-based Survey. The odds ratios (ORs) of suicidal ideation, planning, and attempts were calculated based on parental marital status, living situation, and socioeconomic factors. The data were analyzed using multiple logistic regression.
Results
When compared to those living with 2 married biological parents, the ORs of suicidal ideation among adolescents living with either remarried or no parents were 1.34 (95% confidence interval [CI], 1.17 to 1.53) and 1.36 (95% CI, 1.11 to 1.66), respectively. For suicidal planning, the OR of those living with 1 remarried biological parent was 1.24 (95% CI, 1.01 to 1.52), and that of those living without parents was 1.28 (95% CI, 0.95 to 1.73), when compared to adolescents living with 2 married biological parents. For suicide attempts, when compared to adolescents with 2 married biological parents, the OR of those living with 1 remarried biological parent was 1.48 (95% CI, 1.17 to 1.87) and that of those living without parents was 2.02 (95% CI, 1.44 to 2.83). For adolescents living with 1 remarried biological parent, suicidal behavior was strongly associated with having no siblings and were weakly associated with not living with grandparents.
Conclusions
Suicidal behavior among adolescents was associated with the remarriage and loss of parents. Therefore, special attention and interventions are needed for adolescents in those situations.
Summary

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Educational Intervention Based on the Health Belief Model to Modify Risk Factors of Cardiovascular Disease in Police Officers in Iran: A Quasi-experimental Study
Mohsen Saffari, Hormoz Sanaeinasab, Hassan Jafarzadeh, Mojtaba Sepandi, Keisha-Gaye N. O'Garo, Harold G. Koenig, Amir H. Pakpour
J Prev Med Public Health. 2020;53(4):275-284.   Published online June 18, 2020
DOI: https://doi.org/10.3961/jpmph.20.095
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AbstractAbstract PDFSupplementary Material
Objectives
Police officers may be at a greater risk for cardiovascular disease (CVD) than the general population due to their highstress occupation. This study evaluated how an educational program based on the health belief model (HBM) may protect police officers from developing CVD.
Methods
In this single-group experimental study, 58 police officers in Iran participated in a 5-week intervention based on HBM principles. Outcomes included changes in scores on an HBM scale, time spent on moderate to vigorous physical activity (International Physical Activity Questionnaire), body mass index (BMI), blood lipid profile, blood glucose, and blood pressure. The intervention consisted of 5 HBM-based educational sessions. Follow-up was conducted at 3 months post-intervention. The paired t-test was used to examine differences between baseline and follow-up scores.
Results
All aspects of the HBM scale improved between baseline and follow-up (p<0.05), except the cues to action subscale. Self-efficacy and preventive behaviors improved the most. BMI decreased from 26.7±2.9 kg/m2 at baseline to 25.8±2.4 kg/m2 at follow-up. All components of the lipid profile, including triglycerides, cholesterol, high-density lipoprotein, and low-density lipoprotein, showed significant improvements post-intervention. Blood glucose and blood pressure also decreased, but not significantly. Nearly 25% of participants who were not physically active at baseline increased their physical activity above or beyond the healthy threshold.
Conclusions
A relatively brief educational intervention based on HBM principles led to a significant improvement in CVD risk factors among police officers. Further research is needed to corroborate the effectiveness of this intervention.
Summary

Citations

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