Key Message
Patients undergoing hemodialysis encounter a wide range of complex challenges, underscoring the essential role of self-care in disease management. The findings underscore the effectiveness of an educational program based on Orem’s self-care model in significantly improving self-care behaviors, treatment adherence, and quality of life among hemodialysis patients. The results of this trial carry implications for clinical practice and health policy. It is recommended that contemporary educational methodologies—particularly those grounded in well-established nursing theories such as Orem’s model—be systematically integrated into nursing curricula. Additionally, structured training workshops emphasizing the clinical utility and outcomes of Orem-based self-care education should be incorporated into hospital-based educational programs.