Journal of Preventive Medicine and Public Health

Perspective

Gender in Climate Change: Safeguarding LGBTQ+ Mental Health in the Philippine Climate Change Response From a Minority Stress Perspective: Rowalt Alibudbud; J Prev Med Public Health. 2023;56(2):196-199. Published online March 13, 2023; DOI: https://doi.org/10.3961/jpmph.22.501

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Climate-related events unevenly affect society, worsening mental health disparities among vulnerable populations. This paper highlights that lesbians, gays, bisexuals, transgender, queers, and other individuals identifying as sexual and gender minorities (LGBTQ+) could be considered a climate-vulnerable population in the Philippines, one of the most climate-vulnerable countries. As such, this paper elucidated that LGBTQ+ Filipinos can be marginalized in climate response efforts due to their sexual orientation and gender minority identities. According to the minority stress theory, discrimination against LGBTQ+ individuals may predispose them to mental health problems. Thus, there is a need to institute an LGBTQ+ inclusive mental health response for climate-related events to address discrimination against LGBTQ+ individuals and uphold their mental health.

Summary

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Original Article

Educational Intervention Based on the Health Belief Model to Modify Risk Factors of Cardiovascular Disease in Police Officers in Iran: A Quasi-experimental Study: Mohsen Saffari, Hormoz Sanaeinasab, Hassan Jafarzadeh, Mojtaba Sepandi, Keisha-Gaye N. O'Garo, Harold G. Koenig, Amir H. Pakpour; J Prev Med Public Health. 2020;53(4):275-284. Published online June 18, 2020; DOI: https://doi.org/10.3961/jpmph.20.095

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Abstract PDF Supplementary Material

Objectives
Police officers may be at a greater risk for cardiovascular disease (CVD) than the general population due to their highstress occupation. This study evaluated how an educational program based on the health belief model (HBM) may protect police officers from developing CVD.
Methods
In this single-group experimental study, 58 police officers in Iran participated in a 5-week intervention based on HBM principles. Outcomes included changes in scores on an HBM scale, time spent on moderate to vigorous physical activity (International Physical Activity Questionnaire), body mass index (BMI), blood lipid profile, blood glucose, and blood pressure. The intervention consisted of 5 HBM-based educational sessions. Follow-up was conducted at 3 months post-intervention. The paired t-test was used to examine differences between baseline and follow-up scores.
Results
All aspects of the HBM scale improved between baseline and follow-up (p<0.05), except the cues to action subscale. Self-efficacy and preventive behaviors improved the most. BMI decreased from 26.7±2.9 kg/m² at baseline to 25.8±2.4 kg/m² at follow-up. All components of the lipid profile, including triglycerides, cholesterol, high-density lipoprotein, and low-density lipoprotein, showed significant improvements post-intervention. Blood glucose and blood pressure also decreased, but not significantly. Nearly 25% of participants who were not physically active at baseline increased their physical activity above or beyond the healthy threshold.
Conclusions
A relatively brief educational intervention based on HBM principles led to a significant improvement in CVD risk factors among police officers. Further research is needed to corroborate the effectiveness of this intervention.

Summary

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Climate Change: Review

Research Trends in Agenda-setting for Climate Change Adaptation Policy in the Public Health Sector in Korea: Su-Mi Chae, Daeeun Kim; J Prev Med Public Health. 2020;53(1):3-14. Published online January 31, 2020; DOI: https://doi.org/10.3961/jpmph.19.326

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Abstract Summary PDF Supplementary Material

Many studies have been conducted to assess the health effects of climate change in Korea. However, there has been a lack of consideration regarding how the results of these studies can be applied to relevant policies. The current study aims to examine research trends at the agenda-setting stage and to review future ways in which health-related adaptation to climate change can be addressed within national public health policy. A systematic review of previous studies of the health effects of climate change in Korea was conducted. Many studies have evaluated the effect of ambient temperature on health. A large number of studies have examined the effects on deaths and cardio-cerebrovascular diseases, but a limitation of these studies is that it is difficult to apply their findings to climate change adaptation policy in the health sector. Many infectious disease studies were also identified, but these mainly focused on malaria. Regarding climate change-related factors other than ambient temperature, studies of the health effects of these factors (with the exception of air pollution) are limited. In Korea, it can be concluded that studies conducted as part of the agenda-setting stage are insufficient, both because studies on the health effects of climate change have not ventured beyond defining the problem and because health adaptation to climate change has not been set as an important agenda item. In the future, the sharing and development of relevant databases is necessary. In addition, the priority of agenda items should be determined as part of a government initiative.

Summary

Korean summary
이 연구는 한국에서 수행된 기후변화에 따른 건강영향 연구의 동향을 살펴봄으써, 기후변화 건강 적응이 보건 정책의 어젠다로 자리 잡기 위한 연구 방향을 검토했다. 향후 국가는 기후변화 적응을 위한 우선순위 건강 문제를 검토해야 하며, 관련된 연구의 양과 질을 확보해 국가 전략의 기초가 될 수 있도록 해야 한다.

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Climate Change: Perspective

Characteristics of Heat Waves From a Disaster Perspective: Do-Woo Kim, Chaeyoung Kwon, Jineun Kim, Jong-Seol Lee; J Prev Med Public Health. 2020;53(1):26-28. Published online January 31, 2020; DOI: https://doi.org/10.3961/jpmph.19.315

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Abstract Summary PDF

In September 2018, heat waves were declared to be a type of natural disaster by the Framework Act on the Management of Disasters and Safety. The present study examined the characteristics of heat waves from the perspectives of meteorological phenomena and health damage. The government’s efforts to minimize the damages incurred by heat waves are summarized chronologically. Furthermore, various issues pertaining to heat waves that are being raised in our society despite the government’s efforts are summarized by analyzing big data derived from reported news and academic articles.

Summary

Korean summary
2018년 9월, 폭염이 재난 및 안전 관리 기본법 상 자연재난의 한 유형으로 명시되었다. 본 연구는 다른 자연재난들과 구별되는 폭염 재난의 특징들을 기상학적과 보건학적 측면으로 나누어 제시하였다. 또한 폭염 피해를 줄이기 위한 그간 정부의 각종 노력들을 시간순서대로 정리하였으며, 뉴스와 논문 빅데이터 분석을 통해 최근에 우리사회에서 폭염과 관련된 어떤 이슈들이 떠오르고 있는지도 살펴보았다.

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Original Article

Socio-demographic Characteristics and Leading Causes of Death Among the Casualties of Meteorological Events Compared With All-cause Deaths in Korea, 2000-2011: Kyung Eun Lee, Hyung-Nam Myung, Wonwoong Na, Jae-Yeon Jang; J Prev Med Public Health. 2013;46(5):261-270. Published online September 30, 2013; DOI: https://doi.org/10.3961/jpmph.2013.46.5.261

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Abstract PDF

Objectives

This study investigated the socio-demographic characteristics and medical causes of death among meteorological disaster casualties and compared them with deaths from all causes.

Methods

Based on the death data provided by the National Statistical Office from 2000 to 2011, the authors analyzed the gender, age, and region of 709 casualties whose external causes were recorded as natural events (X330-X389). Exact matching was applied to compare between deaths from meteorological disasters and all deaths.

Results

The total number of deaths for last 12 years was 2 728 505. After exact matching, 642 casualties of meteorological disasters were matched to 6815 all-cause deaths, which were defined as general deaths. The mean age of the meteorological disaster casualties was 51.56, which was lower than that of the general deaths by 17.02 (p<0.001). As for the gender ratio, 62.34% of the meteorological event casualties were male. While 54.09% of the matched all-cause deaths occurred at a medical institution, only 7.6% of casualties from meteorological events did. As for occupation, the rate of those working in agriculture, forestry, and fishery jobs was twice as high in the casualties from meteorological disasters as that in the general deaths (p<0.001). Meteorological disaster-related injuries like drowning were more prevalent in the casualties of meteorological events (57.48%). The rate of amputation and crushing injury in deaths from meteorological disasters was three times as high as in the general deaths.

Conclusions

The new information gained on the particular characteristics contributing to casualties from meteorological events will be useful for developing prevention policies.

Summary

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Brief Report

Trends in Reports on Climate Change in 2009-2011 in the Korean Press Based on Daily Newspapers' Ownership Structure: Jihye Lee, Yeon-pyo Hong, Hyunsook Kim, Youngtak Hong, Weonyoung Lee; J Prev Med Public Health. 2013;46(2):105-110. Published online March 28, 2013; DOI: https://doi.org/10.3961/jpmph.2013.46.2.105; Correction in: J Prev Med Public Health 2013;46(5):291

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Abstract PDF

Objectives

The mass media play a crucial role in risk communication regarding climate change. The aim of this study was to investigate the trend in journalistic reports on climate change in the daily newspapers of Korea.

Methods

We selected 9 daily newspapers in Korea, which according to the ABC Association, represented 77% of newspaper circulation, out of a total of 44 Korean daily newspapers. The collected articles were from 2009 to 2011. All of the articles were sorted into the following 8 categories: greenhouse gas, climate change conventions, sea level rise, Intergovernmental Panel on Climate Change synthesis reports, expected damage and effect, use of fossil fuels, global warming, and mitigation or adaptation. A chi-squared test was done on the articles, which were counted and classified into cause, effect, and measurement of climate change according to the newspaper's majority or minority ownership structure.

Results

From the 9 selected newspapers, the number of articles on climate change by month was greatest in December 2009. Generally, the articles vague about climate change (lack of precise data, negative or skeptical tone, and improper use of terminology) were much more common than the articles presenting accurate knowledge. A statistical difference was found based on ownership structure: the majority-owned newspapers addressed the cause of climate change, while the minority-owned newspapers referred more to climate change measurement.

Conclusions

Our investigation revealed that generally Korean daily newspapers did not deliver accurate information about climate change. The coverage of the newspapers showed significant differences according to the ownership structure.

Summary

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Original Article

Trends in Gender-based Health Inequality in a Transitional Society: A Historical Analysis of South Korea: Heeran Chun, Sung-Il Cho, Young-Ho Khang, Minah Kang, Il-Ho Kim; J Prev Med Public Health. 2012;45(2):113-121. Published online March 31, 2012; DOI: https://doi.org/10.3961/jpmph.2012.45.2.113

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Abstract PDF

Objectives

This study examined the trends in gender disparity in the self-rated health of people aged 25 to 64 in South Korea, a rapidly changing society, with specific attention to socio-structural inequality.

Methods

Representative sample data were obtained from six successive, nationwide Social Statistics Surveys of the Korean National Statistical Office performed during 1992 to 2010.

Results

The results showed a convergent trend in poor self-rated health between genders since 1992, with a sharper decline in gender disparity observed in younger adults (aged 25 to 44) than in older adults (aged 45 to 64). The diminishing gender gap seemed to be attributable to an increase in women's educational attainment levels and to their higher status in the labor market.

Conclusions

The study indicated the importance of equitable social opportunities for both genders for understanding the historical trends in the gender gap in the self-reported health data from South Korea.

Summary

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Research Support, Non-U.S. Gov't

Changes in Labor Regulations During Economic Crises: Does Deregulation Favor Health and Safety?.: Won Gi Jhang; J Prev Med Public Health. 2011;44(1):14-21.; DOI: https://doi.org/10.3961/jpmph.2011.44.1.14

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OBJECTIVES
The regulatory changes in Korea during the national economic crisis 10 years ago and in the current global recession were analyzed to understand the characteristics of deregulation in labor policies. METHODS: Data for this study were derived from the Korean government's official database for administrative regulations and a government document reporting deregulation. RESULTS: A great deal of business-friendly deregulation took place during both economic crises. Occupational health and safety were the main targets of deregulation in both periods, and the regulation of employment promotion and vocational training was preserved relatively intact. The sector having to do with working conditions and the on-site welfare of workers was also deregulated greatly during the former economic crisis, but not in the current global recession. CONCLUSIONS: Among the three main areas of labor policy, occupational health and safety was most vulnerable to the deregulation in economic crisis of Korea. A probable reason for this is that the impact of deregulation on the health and safety of workers would not be immediately disclosed after the policy change.

Summary

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The Vulnerability of Occupational Health and Safety to Deregulation: The Weakening of Information Regulations during the Economic Crisis in Korea
Won Gi Jhang
NEW SOLUTIONS: A Journal of Environmental and Occupational Health Policy.2018; 28(1): 151. CrossRef
The association between nonstandard work and occupational injury in Korea
Hyoung‐June Im, Dae‐gyu Oh, Young‐Su Ju, Young‐Jun Kwon, Tae‐Won Jang, Jun Yim
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English Abstract

Correlations Between Climate Change-Related Infectious Diseases and Meteorological Factors in Korea.: Si Heon Kim, Jae Yeon Jang; J Prev Med Public Health. 2010;43(5):436-444.; DOI: https://doi.org/10.3961/jpmph.2010.43.5.436

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Abstract PDF

OBJECTIVES
Infectious diseases are known to be affected by climate change. We investigated if the infectious diseases were related to meteorological factors in Korea. METHODS: Scrub typhus, hemorrhagic fever with renal syndrome (HFRS), leptospirosis, malaria and Vibrio vulnificus sepsis among the National Notifiable Infectious Diseases were selected as the climate change-related infectious diseases. Temperature, relative humidity and precipitation were used as meteorological factors. The study period was from 2001 through 2008. We examined the seasonality of the diseases and those correlations with meteorological factors. We also analyzed the correlations between the incidences of the diseases during the outbreak periods and monthly meteorological factors in the hyper-endemic regions. RESULTS: All of the investigated diseases showed strong seasonality; malaria and V. vulnificus sepsis were prevalent in summer and scrub typhus, HFRS and leptospirosis were prevalent in the autumn. There were significant correlations between the monthly numbers of cases and all the meteorological factors for malaria and V. vulnificus sepsis, but there were no correlation for the other diseases. However, the incidence of scrub typhus in hyper-endemic region during the outbreak period was positively correlated with temperature and humidity during the summer. The incidences of HFRS and leptospirosis had positive correlations with precipitation in November and temperature and humidity in February, respectively. V. vulnificus sepsis showed positive correlations with precipitation in April/May/July. CONCLUSIONS: In Korea, the incidences of the infectious diseases were correlated with meteorological factors, and this implies that the incidences could be influenced by climate change.

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Comparative Study

Body Weight at Birth and at Age Three and Respiratory Illness in Preschool Children.: Yoolwon Jeong, Kyunghee Jung-Choi, Jin Hwa Lee, Hwa Young Lee, Eun Ae Park, Young Ju Kim, Eunhee Ha, Se Young Oh, Hyesook Park; J Prev Med Public Health. 2010;43(5):369-376.; DOI: https://doi.org/10.3961/jpmph.2010.43.5.369

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OBJECTIVES
The purpose of this study was to examine the associations of current body weight and body mass index (BMI) at age three and birth weight in developing chronic respiratory illness in childhood and identify possible interaction underlying its mechanism. METHODS: The study was carried out with 422 children who were enrolled in a hospital-based birth cohort. Birth related anthropometric data were collected at birth. At age 3 years, the presence of respiratory symptoms was evaluated by using the Korean version of core questionnaire for wheezing and asthma from the International Study of Asthma and Allergies in Childhood (ISAAC). Physical examination was carried out to measure the child's weight and height. RESULTS: Children in the lowest birth weight tertile (aOR = 3.97, 95% CI = 0.94-16.68) or highest BMI tertile (aOR = 3.68, 95% CI = 1.24-10.95) at three years of age were at an increased risk of chronic respiratory illness. Children who were initially in the lowest birth weight tertile but now belong in the highest weight tertile had higher risk of chronic respiratory illness compared to those who had remained in the middle tertile (OR=16.35, 95% CI=1.66-160.57). CONCLUSIONS: Children with lower birth weight or higher BMI were at an increased risk of chronic respiratory illness. In addition, children who were initially in the lowest birth weight tertile but are now in the highest weight tertile had higher risk of chronic respiratory illness compared to those who remained in the middle tertile.

Summary

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English Abstracts

The Association Between Public Social Expenditure and Suicides: Evidence from OECD Countries.: Yoojin Park, Myoung hee Kim, Soonman Kown, Young jeon Shin; J Prev Med Public Health. 2009;42(2):123-129.; DOI: https://doi.org/10.3961/jpmph.2009.42.2.123

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Abstract PDF

OBJECTIVES
This study aimed to examine the association between public social expenditure (PSE) and suicides in the 27 countries of the Organization for Economic Cooperation and Development (OECD) from 1980 to 2003. METHODS: The age-standardized suicide rates and their annual change (%) were obtained from the OECD Health Data 2007. As a measure of social protection, the PSE (% GDP) was used. The covariates included the annual divorce rate (/100,000 population), fertility rate (number of children/woman aged 15 to 49 years), GDP per capita (US$PPP), male unemployment rate (%), life expectancy (years) and alcohol consumption (liter/capita) for each country, which were all obtained from the OECD Health Data 2007 and the OECD Social Indicators 2006. Using hierarchical linear models that included these covariates, the effects of PSE on suicides (Model 1) and the annual percent change (Model 2) were examined (Model 3). Also, sub-sample analyses were done for six countries that experienced political/economic transition. RESULTS: We could not find significant effects of PSE on suicides (Model 1), but we observed significantly negative effects on the annual percent change for men and women (Model 2). Such findings were replicated in the sub-sample analysis, and moreover, the effect size was much larger (Model 3). CONCLUSIONS: Our finding suggests that social welfare protection can be a pivotal factor for suicide epidemiology, and especially in countries experiencing a social crisis or transition.

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Mert Akyuz
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Changsook Lee, Sun-Young Heo
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Epidemiology and Psychiatric Sciences.2018; 27(1): 62. CrossRef
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Therese Saltkjel, Mari Holm Ingelsrud, Espen Dahl, Knut Halvorsen
Scandinavian Journal of Public Health.2017; 45(18_suppl): 48. CrossRef
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Chiara Piovani, Nursel Aydiner-Avsar
Forum for Social Economics.2015; 44(1): 18. CrossRef
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Eun-Won Seo, Jin-Mi Kwak, Da-Yang Kim, Kwang-Soo Lee
Health Policy and Management.2015; 25(4): 285. CrossRef
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Journal of Preventive Medicine and Public Health.2012; 45(2): 70. CrossRef
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Experience of Parent-related Negative Life Events, Mental Health, and Delinquent Behavior among Korean Adolescents.: Dong Sik Kim; J Prev Med Public Health. 2007;40(3):218-226.; DOI: https://doi.org/10.3961/jpmph.2007.40.3.218

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Abstract PDF

OBJECTIVES
This study examined the relationship of parent-related negative life events with mental health and delinquent behaviors among Korean adolescents. METHODS: A total of 2,976 high school first-grade pupils (1,498 boys & 1,478 girls) taking part in the third wave of Korean Youth Panel Survey completed a self-administered questionnaire regarding parent-related life events, depressive feelings, suicidal ideation, delinquent behaviors, demographic characteristics, parental socioeconomic status, social support, and social capital. Data analyses were conducted using multivariate logistic regression. RESULTS: After adjusting for all covariates, the more parent-related negative life events adolescents experienced throughout their whole life, the more likely adolescent were to have mental and behavioral problems. A significant dose-response relationship between them was more clearly observed in girls than in boys. The experience of parentrelated negative events during childhood was significantly associated with suicidal ideation and delinquent behaviors for boys, and with depressive feelings for girls during adolescence. Indeed, parental social support, social capital, and having a close friend with delinquent behaviors, especially for girls, partially mediated the relationship between parent-related negative life events and both outcomes. CONCLUSIONS: The study showed a clear dose-response relationship of frequency of parent-related negative life events with poor mental and behavioral health for both genders. The residual effect of being exposed to parentrelated events during childhood on mental health and delinquent behaviors during adolescence still remained.

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Se-Hwan Jung, Myoung-Hee Kim, Jae-In Ryu
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The effects of negative life events in pre-adulthood on adulthood depression: Mediator effect of interpersonal maladjustment
Joo Won Jung
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Parenting and Youth Psychosocial Well- Being in South Korea using Fixed-Effects Models
Yoonsun Han, Andrew Grogan-Kaylor
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Jun Sung Hong, Na Youn Lee, Andrew Grogan-Kaylor, Hui Huang
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Elza Maria de Souza
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Dong-Sik Kim, Hyun-Sun Kim
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Original Articles

Neurobehavioral Change on the Lead Exposure Workersq.: In Geun Park, Duk Hee Lee, Yong Hwan Lee, Jin Ha Kim, She Han Jang; Korean J Prev Med. 1995;28(1):175-186.

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Abstract PDF: No abstract available.; Summary

Twelve-year Study on Body Mass Index Changes of Obese Adolescents.: Yun Ju Kang, Il Suh, Chang Ho Hong, Jong Ku Park; Korean J Prev Med. 1994;27(4):665-676.

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Abstract PDF: The purpose of this study is to observe the longitudinal changes in BMI (Body Mass Index) of obese and non-obese 3rd. grade high school students in Seoul for 12 years and to see the trends of overt weight gain in obese adolescents. The results are as follows; 1. The average annual increasing rates of body mass indices in male students were 1.14kg/m2 in obese group and 0.59 in non-obese group. In female students, the average annual increasing rates of body mass indices were 0.93kg/m2 in obese group and 0.53kg/m2 in non-obese group. 2. The change rate of BMI for 12 years was significantly higher in obese group than non-obese group. 3. Puberty had less influence on the change rate of BMI in obese group compared to non-obese group. 4. In obese group, 71.8% of the variance in BMI at 17 can be predicted by BMI at 16 years in male students. In female students 44.4% can be predicted by BMI at age 16. 5. Among the 17-year-old obese students, 58.8% of the males and 56.2% of females were found not to have been obese at 7 years of age. 6. Among the 17-year-old obese students, those who were obese at 7 years of age were found to have higher BMI at later ages than those who were in the non-obese group. Obese adolescents were more likely to be obese in their childhood than non-obese group. There was no optimal age for the significant weight gain and the increasing rate of BMI was constantly higher in obese group than in non-obese group. Due to the fact that child obesity in early age contributes to obesity in adolescence, close observation is advised on the other hand, a large proportion of obese adolescents can be preventable by early interventions, because about 50% of obese adolescents were not obese in early elementary school age.; Summary

Chromosome Aberrations and Sister Chromatid Exchanges of Hospital Workers Exposed to Radiation.: Ae Ri Cha, Mi Sun Kim, In Kyung Hwang, Su Ill Lee, Byung Mann Cho, Don Kyoun Kim; Korean J Prev Med. 1998;31(4):616-627.

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Abstract PDF: In order to evaluate the cytogenetic hazard among hospital workers potentially exposed to low dose of radiation, the analysis of chromosome aberrations(CA) and sister chromatid exchanges(SCE) in lymphocytes were performed in 79 hospital workers and 79 non-exposed workers. The mean frequency of chromosomal exchange and deletion(respectively, 0.20X10-2/cell and 0.39X10(-2)/cell) in the exposed group were significantly higher than those(0.07X10(-2)/cell and 0.23X10-2/cell) in control group. The frequency of sister chromatid exchanges was 5.04/cell in the control vs. 6.57/cell in the exposed group. There were also significant differences in the mean frequencies of CA and SCE adjusted for age, sex, smoking, drinking between two groups. There were no evidence of significant increase of CA and SCE according to the department or duration of employment. But the frequency of cells having chromosome aberration was significantly higher in the exposed group than in the control group related to duration of employment. There was no dose-effect relationship between the cumulative doses and the frequency of CA and SCE. But in the case of last 1 yr cumulative dose, there were evidence of significant dose-dependant increase of chromosome type CA and percentage of cells with aberration. The result suggest that there is cytogenetic hazard in risk group like hospital workers handling low dose radiation. And the analysis CA and SCE are useful biological indicators for the exposure of low dose level of radiation.; Summary

A study to the workers exposed to organic solvents by neurobehavioral tests.: Seong Kyu Kang, Ho Keun Chung, Jeong Pyo Hong, Ki Woong Kim, Young Sook Cho; Korean J Prev Med. 1993;26(2):210-221.

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Abstract PDF: In order to evaluate the confounding factors of neurobehavioral tests and the neurobehavioral effects in the workers exposed to organic solvents, NCTB was carried out on 100 workers. 46 workers had never been exposed to neurotoxic substances, and the others were being exposed to the solvents, mainly toluene. Simple reaction time, digit symbol, Santa Ana dexterity test and persuit aiming were different with age in non exposure group. Simple reaction time was carried out well in males, and digit symbol and persuit aiming were in females. There was no difference at educational level when the subject was educated over 12 years. Santa Ana dexterity and Benton visual test differed according to exposure level to toluene, however simple reaction time didn't. The acute neurotoxic effect was not excluded in this study. But, NCTB could be used to evaluate and prevent neurobehavioral changes in workers exposed to neurotoxic solvents in Korea.; Summary

Concentration of Urinary Cotinine and Frequency of Sister Chromatid Exchange in Lymphocytes among Male Adolescents.: Dong Ki Paek, Seong Sil Chang, Tae Yong Lee, Young Man Roh, Yeonkyeng Lee, Young Chae Cho, Dong Bae Lee; Korean J Prev Med. 2001;34(3):269-276.

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Abstract PDF: OBJECTIVES
To evaluate the internal burden and hazardous effects associated with smoking in middle and high school students. METHODS: We analysed urinary cotinine (U-cotinine) concentrations and the frequency of Sister Chromatid Exchanges (SCE). A comparison was done of U-cotinine concentrations and the frequency of SCE in peripheral lymphocytes across school levels (middle vs. high) and smoking types (direct: daily & occasional smoking, indirect: usual indirect & non-smoking), in 122 males. RESULTS: The middle school student group comprised 6.8% daily smokers, 15.9% occasional smokers, 40.9% daily indirect smokers, and 35.4% nonsmokers, while the high school student group comprised 18.0%, 20.5%,39.7%, and 21.8%, respectively. The U-cotinine concentration and the frequency of SCE among the middle school students were 79.11 microgram/literand 2.0 per cell, respectively, which were significantly lower than the 146.85 microgram/liter (p=0.078) and 2.6 per cell (p=0.005) of the high school students. Among the 40 direct smokers, these two biomarkers were 235.66 microgram/literand 2.59 per cell, significantly higher than the 67.33 microgram/liter (p=0.0001) and2.1 per cell (p=0.003) among indirect smoking groups. The variation in individual U-cotinine concentration ranged widely in both the indirect and direct smoking groups. CONCLUSION: Urinary cotinine concentrations and the frequency of Sister Chromatid Exchange seem to objectively and effectively evaluate student exposure whether it was direct or indirect smoking. Consequently, these biomarkers may be useful in monitoring the objective efficacy of anti-smoking programs in adolescent populations.; Summary

Four-year change and tracking of serum lipids in Korean adolescents.: Kang Hee Lee, Il Suh, Sun Ha Jee, Chung Mo Nam, Sung Soon Kim, Won Heum Shim, Jong Won Ha, Suk Il Kim, Hyung Gon Kang; Korean J Prev Med. 1997;30(1):45-60.

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Abstract PDF: It has been known that there is a tracking phenomenon in the level of serum lipids. However, no study has been performed to examine the change and tracking of serum lipids in Korean adolescents. The purpose of this study is to examine the changes of serum lipids in Korean adolescents from 12 to 16 years of age, and to examine whether or not there is a tracking phenomenon in serum lipids level during the period. In 1992 serum lipids(total cholesterol(TC), triglyceride(TG), LDL cholesterol(LDL-C), HDL cholesterol(HDL-C)) were measured in 318 males, 365 females who were 12 years of age in Kangwha county, Korea. These participants have been followed up to 1996 and serum lipids level were examined in 1994 and 1996. Among the participants 162 males and 147 females completed all three examinations in fasting state. To examine the effect of eliminating adolescents with incomplete data, we compared serum lipids, blood pressure and anthropometric measures at baseline between adolescents with complete follow-up and adolescents who were withdrawn. To examine the change of serum lipids we compared mean values of serum lipids according to age in males and females. Repeated analysis of variance was used to test the change according to age. We used three methods to examine the existence of tracking. First, we analyzed the trends in serum lipids over 4-year period within quartile groups formed on the basis of the first-year serum lipids level to see whether or not the relative ranking of the mean serum lipids among the quartile groups remained in the same group for 4-year period. Second, we quantified the degree of tracking by calculating Spearman's rank correlation coefficient between every tests. Third, the persistence extreme quartile method was used. This method divides the population into quartile groups according to the initial level of blood lipids and then calculates the percent of the subjects who stayed in the same group at follow-up measurement. The decreases in levels were noted during 4 years for TC, LDL-C, primarily for boys. The level of HDL-C decreased between baseline and first follow-up for both sexes and girls. Tracking, as measured by both correlation coefficients and persistence extreme quartiles, was evident for all of the lipids. The correlation coefficients of TC between baseline and 4 years later in boys and girls were 0.55 and 0.68, respectively. And the corresponding values for HDL-C were 0.58 and 0.69. More than 50% of adolescents who belonged to the highest quartile group in TC, HDL-C and LDL-C at the baseline were remained at the same group at the examination performed 2 years later for both sexes. The probability of remaining at the same group was more than 35% when examined 4 years later. The tracking phenomenon of TG was less evident compared with the other lipids. Percents of girls who stayed at the same group 2 years later and 4 years later were 42.9% and 25.7%, respectively. It was evident that serum lipid levels tracked in Korean adolescents. Researches with longer follow-up would be needed in he future to investigate the long-term change of lipids from adolescents to adults.; Summary

Impacts of DRG Payment System on Behavior of Medical Insurance Claimants.: Beom Man Ha, Gilwon Kang, Hyoung Keun Park, Chang Yup Kim, Yong Ik Kim; Korean J Prev Med. 2000;33(4):393-401.

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Abstract PDF: OBJECTIVES
To evaluate the impacts of the DRG payment system on the behavior of medical insurance claimants. Specifically, we evaluated the case-mix index, the numbers of diagnosis and procedure codes utilized, and the corresponding rate of diagnosis codes before, during and after implementation of the DRG payment system. METHODS: In order to evaluate the case-mix index, the number of diagnosis and procedure codes utilized, we used medical insurance claim data from all medical facilities that participated in the DRG-based Prospective Payment Demonstration Program. This medical insurance claim data consisted of both pre-demonstration program data (fee-for-service, from November, 1998 to January, 1999) and post-demonstration program data (DRG-based Prospective Payment, from February, 1999 to April, 1999). And in order to evaluate the corresponding rate of diagnosis codes utilized, we reviewed 820 medical records from 20 medical institutes that were selected by random sampling methods. RESULTS: The case-mix index rate decreased after the DRG-based Prospective Payment Demonstration Program was introduced. The average numbers of different claim diagnosis codes used decreased (new DRGs from 2.22 to 1.24, and previous DRGs from 1.69 to 1.21), as did the average number of claim procedure codes used (new DRGs from 3.02 to 2.16, and previous DRGs from 2.97 to 2.43). With respect to the time of participation in the program, the change in number of claim procedure codes was significant, but the change in number of claim diagnosis codes was not. The corresponding rate of claim diagnosis codes increased (from 57.9% to 82.6%), as did the exclusion rate of claim diagnosis codes (from 16.5% to 25.1%). CONCLUSIONS: After the implementation of the DRG payment system, the corresponding rate of insurance claim codes and the corresponding exclusion rate of claim diagnosis codes both increased, because the inducement system for entering the codes for claim review was changed.; Summary

The Relationship between Change in Obesity Indices and Change in Serum Lipids in Adult Male Workers.: Young Ae Ha, Byung Yeol Chun, Sin Kam, Sung Kook Lee, Min Hae Yeh; Korean J Prev Med. 1996;29(3):439-450.

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Abstract PDF: This study was conducted to evaluate the relationship between change in obesity indices and change in serum lipids in adult male workers. Two-hundred-eight adult male workers of an industry in Taegu city were followed-up from 1991 to 1995. Height, weight, circumferences of hip and waist, blood pressure were measured and serum lipids were analysed. Data on life style were obtained using self-administered questionnaires. Mean differences of anthropometric measurements between 1991 and 1995 were as follows; 1.63kg in weight, 3.61cm in waist circumferences, 4.23cm in hip circumferences, 0.52kg/m2 in BMI and -0.021 in WHR. Those of lipids were as follows; 15.09mg/dl in total cholesterol, 20.43mg/dl in triglyceride, 9.40mg/dl in HDL-cholesterol, 2.87 in MI-index(p<0.01) and 350mg/dl in LDL-cholesterol. The changed value of BMI and Katsura index were strongly correlated with that of total cholesterol(r=0.174, p<0.05), the changed value of BMI correlated with that of triglyceride(r=0.374, p<0.01) and the changed value of weight correlated with that of MI index(r=-0.173, p<0.05). The changed value of WHR was significantly correlated with that of total cholesterol(r=0.162, p<0.05), however, was not significantly correlated with HDL-cholesterol, LDL-cholesterol, triglyceride and MI index. The changed value of weight, BMI and Katsura index were correlated with that of triglyceride(r=0.262, p<0.01; r=0.267, p<0.01; r=0.258, p<0.01) and the changed value of MI index(r=-0.143, p<0.05; r=-0.158; r=-0.144, p<0.01), adjusting the pattern of change in life style. The changed values of HDL-cholesterol and MI index between 1991 and 1995 in low WHR group were significantly higher than those in high WHR group(p<0.05, p<0.01), adjusting the baseline value of them. Similar pattern was observed when considering Katsura index. When stratifying by BMI value of 1991, in low BMI group, the changed value of HDL-cholesterol and MI index showed the same pattern as above, however the of triglyceride was statistically higher in obese group than in non obese group(p<0.05). In conclusion BMI might be a better indicator to predict serum lipids change than other obesity indices.; Summary

Sister Chromatid Exchanges in Lymphocytes of Some Workers Exposed to Hexavalent Chromium.: Dong Hoon Shin, Nung Ki Yoon, Suk Kwan Suh, Min Hae Yeh; Korean J Prev Med. 1990;23(3):358-368.

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Abstract PDF: To investigate the possibility of utilizing of sister chromatid exchange(SCE) analysis in lymphocytes as an indicator which could evaluate the effects of mutagenicity after in vivo exposure to hexavalent chromium, this study was conducted using some of chromium plating workers occupationally exposed to hexavalent chromium, chromium trioxide (CrO3) in Taegu city. The study population was 12 Cr platers with perforation of nasal septum, 12 Cr platers without perforation of nasal septum and 20 controls. The SCE in peripheral blood lymphocytes of the subjects was analyzed and blood chromium concentration was estimated using the atomic absorption spectrophotometer (IL 551) equipped with furnace atomizer (IL 755). The mean SCE frequencies for Cr platers with and without perforation of nasal septum were statistically higher than those for control. The difference in SCE frequencies by age, smoking habits were not statistically significant both in Cr platers and controls. There was no difference in SCE frequencies by career of Cr platers workers. In Cr platers, the correlation between the mean SCE frequencies and chromium concentration in blood was not statistically significant. Using the transformation y=(sum SCE)1/2+(sum SCE+1)1/2, when the data was studied by multiple regression, it appeared that the influence of the occupation was the most important. Age, smoking, occupation and CrB(blood chromium concentration) together explain only 32.3% of interpersonal variation on SCE. The results in this study suggest that a genetic risk due to occupationally exposure to hexavalent chromium is clearly inferable and thus, SCE analysis in human lymphocytes may be used indicator of biological toxic effects of chromium. Further, populatio analysis studies are required before SCE frequency can be used as a mutagenic indicator in human population.; Summary

A Study on the Induction of Sister-Chromadd Exchanges in Chinese Hamster Ovary Kl Cells by Exposure to Cadmium.: In Kyung Hwang, Don Kyoun Kim; Korean J Prev Med. 1990;23(2):178-184.

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Abstract PDF: In order to exmaine the mutagenicity of cadmium dichloride the author studied the induction of sister chromatid exchanges in chinese hamster ovary K1 cells which treated with cadmium dichloride at various concentrations. The results obtained were as follows: 1. In cells treated with 10(-4) M cadmium dichloride, a small number of cells were visable but no mitosis was bound. 2. The frequencies of sister chromatid exchanges in cells treated with 10(-5) M and 10(-6) M cadmium dichloride as 10.7 +/- 1.9 and 8.3 +/- 2.1, respectively, were significantly increased for control (6.0 +/- 2.3). (p<0.05). 3. There were dose-dependent relationship between the concentration of cadmium dichloride and frequency of sister chromatid exchanges in cells treated with cadmium dichloride at concentration ranging from 10(-5) to 10(-7) M.; Summary

Selenium Effect on the Frequency of SCEs Induced by Heavy Metals in Human Lymphocytes.: Dai Ha Koh, No Suk Ki; Korean J Prev Med. 1990;23(1):1-10.

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Abstract PDF: The protective effect of sodium selenite (Na2SeO3) against the cytogenetic toxicity of heavy metals was investigated on human whole-blood cultures in relation to induction of sister chromatid exchange(SCE) in secondary metaphase chromosome. Methlmercury chloride (CH3HgCl), cadmium chloride (CdCl2), Potassium dichromate (K2Cr2O7), and sodium selenite caused to the typically dose-dependent increase in sister chromatid exchanges (SCEs) by the concentrations ranging from 0.3 micro M to 10 micro M. However, the inductions of sister chromatid exchanges by methymercury chloride or cadmium chloride were inhibited by the simultaneous addition of sodium selenite 1.2 micro M. The frequencies of SCE were decreased to the level of control in the molar ratios as 2 : 1, 1 : 1, 1 : 2, and 1 : 4 of selenium selenite vs. methylmercury chloride, and as 1 : 1 and 1 : 2 of selenium selenite vs. cadmium chloride, while the frequencies of SCE induced by potassium dichromate were not changed by the addition of sodium selenite in culture condition. Mitotic indices were decreased in the higher concentrations of chemicals and not significantly changed by the simultaneous addition of sodium selenite to the culture condition containing each chemicals.; Summary

The effects of chromium exposure on sister chromatid exchange and concentration of 8-hydroxydeoxyguanosine.: Sang Hwan Han, Soo Hun Cho, Heon Kim, Soo Min Park, Mina Ha, Young Soo Joo, Ho Jang Kwon, Yong Dae Kwon, Myung Hee Kwon; Korean J Prev Med. 1995;28(2):511-525.

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Abstract PDF: To elucidate some DNA adducts as a biological marker for workers of chromate pigment, the effects of chromium exposure on the formation of 8-hydroxydeoxyguanosine(8-OH-dG) and sister chromatid exchanges(SCEs) frequency in 38 workers of a pigment plant in Bucheon which utilized lead chromates, were examined. The chromium contents of venous blood and urine were measured as working environmental exposure level. The concentrations of 8-OH-dG in DNA isolated from lymphocytes were determined with high performance liquid chromatography and electrochemical detector and denoted as a molar ratio of 8-OH-dG to deoxyguanosine(dG). The SCEs frequency were analyzed in DNA isolated from lymphocytes. A significant correlation was found between creatinine adjusted urine chromium concentration and the molar ratio of 8-OH-dG to dG(r=0.47, p<0.01). After adjusting the current smoking habit, the correlation coefficient was increased(r=0.62, p<0.05). However, there was no significant correlation between the SCE frequency and chromium exposure. This significant results between molar ratio of 8-OH-dG to dG and chromium exposure are in good agreement with in vitro studies that support the importance of DNA adduct formation for the carcinogenic effect of chromium.; Summary

Neurobehavioral Changes according to Cumulative Exposure of Complex Organic Solvents.: Duk Hee Lee, In Geun Park, Jin Ha Kim, Young Hawn Lee, Sung Gye Kang, Doo Hie Kim; Korean J Prev Med. 1995;28(2):386-397.

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Abstract PDF: A cross sectional study was performed to evaluate the neurobehavioral effects of chronic exposure of complex organic solvents, using NCTB(Neurobehavioral Core Test Battery) recommended by WHO(World Health organization). Forty female shoe factory workers and twenty-two controls matched with age were participated. The tests were performed in the morning before start of work, to exclude the effects of acute exposure. Workers were exposed mainly to toluene, methyl ethyl ketone, n-hexane, cyclo-hexane, dichloroethylene, trichloroethylene, benzene, xylenes etc. The ranges of present solvent exposure of hygienic effect were 0.46~0.71 in the process using adhesives indirectly, and 1.83-2.39 in the process using it directly. We reclassified the subjects, according to cumulative exposure. It showed significantly poorer performances in high exposed group on Santa Ana Dexterity and Benton visual Retention, compared with control group. After controlling confounder, the significances were still remained. But, further cohort studies, having the information of personal exposure dose from entering a factory, are required to clarify the effects of chronic exposure of complex organic solvents in relation to dose and duration of exposure.; Summary

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