Original Article
- The Relationship Between Thiamine Intake and Long Sleep Duration: Results From the Korea National Health and Nutrition Examination Survey
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Dongkyu Lee, Kwanghyun Kim, Youngrong Lee, Kyungwon Oh, Sun Jae Jung
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J Prev Med Public Health. 2022;55(6):520-528. Published online October 14, 2022
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DOI: https://doi.org/10.3961/jpmph.22.313
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13,628
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Abstract
Summary
PDF
Supplementary Material
- Objectives
Thiamine is thought to modify sleeping patterns, while alcohol use diminishes internal thiamine levels. We investigated the association between thiamine intake and sleep duration and explored possible heterogeneity in the effect according to alcohol use.
Methods
In total, 15 384 participants aged 19-64 were obtained from the Korea National Health and Nutrition Examination Survey 2012-2016. Nutrient intake, including thiamine, was measured using a food frequency questionnaire. Sleep duration was measured by a self-reported questionnaire. The highest thiamine intake quartile was set as the reference group. Participants were divided into 3 groups, with 7-8 hours of daily sleep as a reference group and those who slept more or less than that as “oversleeping” and “insufficient sleeping,” respectively. Multivariate logistic regression was used, adjusting for socioeconomic, medical, and nutritional factors. Additionally, participants were stratified according to high-risk alcohol use defined by the World Health Organization standards on alcohol use.
Results
Low thiamine intake was associated with oversleeping (Q3: odds ratio [OR], 1.06; 95% confidence interval [CI], 0.86 to 1.32; Q2: OR, 1.24; 95% CI, 0.99 to 1.55; Q1: OR, 1.49; 95% CI, 1.16 to 1.91) and showed a significant trend for higher ORs at lower intake levels (p-trend<0.001). The effect was stronger in the high-risk alcohol use group (Q1: OR, 1.78; 95% CI, 1.28 to 2.49).
Conclusions
Low thiamine intake was associated with oversleeping, and alcohol use intensified that association. These results were found in a context where overt clinical symptoms due to thiamine deficiency are considered rare. More awareness of the potential relationship of thiamine intake with oversleeping and its related risks should be considered.
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Summary
Korean summary
국민건강영양조사 자료에서 낮은 비타민 B1 섭취가 과도한 수면시간과 연관성이 있으며, 고위험 알코올 섭취군에서 더 큰 상관성을 보였다. 현저한 임상 증상이 나타나지 않는 선에서의 섭취부족도 잠재적으로 과도한 수면시간 및 이와 관련된 건강에 대한 부정적 효과들과 관련이 있을 수 있어 주의가 필요하다.
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Citations
Citations to this article as recorded by

- Sleep Disturbances and Vitamin D in Celiac Patients Under a Gluten Free Diet: A Cross-Sectional Study
Giuseppe Losurdo, Francesco Squeo, Angela Marotti, Antonio Giangaspero, Enzo Ierardi, Mariabeatrice Principi
Diseases.2026; 14(8): 279. CrossRef - Host–Gut Microbiota Interactions: Exploring the Potential Role of Vitamin B1 and B2 in the Microbiota–Gut–Brain Axis and Anxiety, Stress, and Sleep Quality
Yingxuan Tao, Murong Wu, Boyao Su, Heng Lin, Qianzi Li, Yuhong He, Tian Zhong, Ying Xiao, Xi Yu
Nutrients.2025; 17(11): 1894. CrossRef - Daytime-Dependent Effects of Thiamine on the Thiamine Pool and Pyruvate Dehydrogenase Regulation in the Brain and Heart
Vasily Aleshin, Nadejda Borisova, Artem Artiukhov, Kurban Tagirov, Olga Solovjeva, Eva Lavrenteva, Nikolay Panin, Maria Maslova, Anastasia Graf
International Journal of Molecular Sciences.2025; 26(17): 8296. CrossRef - The Therapeutic Potential of Vitamins B1, B3 and B6 in Charcot–Marie–Tooth Disease with the Compromised Status of Vitamin-Dependent Processes
Victoria Bunik
Biology.2023; 12(7): 897. CrossRef - Enhancing Sleep Quality: Assessing the Efficacy of a Fixed Combination of Linden, Hawthorn, Vitamin B1, and Melatonin
Matteo De Simone, Rosario De Feo, Anis Choucha, Elena Ciaglia, Francis Fezeu
Medical Sciences.2023; 12(1): 2. CrossRef
COVID-19: Original Article
- Associations Between General Perceptions of COVID-19 and Posttraumatic Stress Disorder in Korean Hospital Workers: Effect Modification by Previous Middle East Respiratory Syndrome Coronavirus Experience and Occupational Type
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Youngrong Lee, Kwanghyun Kim, Sungjin Park, Sun Jae Jung
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J Prev Med Public Health. 2021;54(2):86-95. Published online January 19, 2021
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DOI: https://doi.org/10.3961/jpmph.20.540
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9,756
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228
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6
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Abstract
Summary
PDF
Supplementary Material
- Objectives
This study investigated associations between perceptions of coronavirus disease 2019 (COVID-19) and the prevalence of posttraumatic stress disorder (PTSD) in workers at hospitals designated to treat COVID-19, as well as the difference in the magnitude of these associations by occupational type and previous Middle East respiratory syndrome coronavirus (MERS-CoV) experience.
Methods
The participants were workers at hospitals designated to treat COVID-19 who completed a questionnaire about their perceptions related to COVID-19, work experience during the previous MERS-CoV outbreak, and symptoms of PTSD ascertained by the PTSD Checklist for the Diagnostic and Statistical Manual of Mental Disorders. Participants’ characteristics were compared using the chi-square test. Multivariable logistic regression was performed to evaluate the associations between perceptions and the prevalence of PTSD, stratified by occupational type and previous MERS-CoV experience.
Results
Non-medical personnel showed stronger associations with PTSD than medical personnel according to general fear (odds ratio [OR], 6.67; 95% confidence interval [CI], 1.92 to 23.20), shortages of supplies (OR, 1.29; 95% CI, 1.07 to 1.56), and issue-specific fear (OR, 1.29; 95% CI, 1.05 to 1.59). Those with prior MERS-CoV quarantine experience were more prone to PTSD than those without such experience in terms of general fear (OR, 1.70; 95% CI, 1.22 to 2.37), shortages of supplies (OR, 1.24; 95% CI, 1.10 to 1.40), and issue-specific fear (OR, 1.21; 95% CI, 1.06 to 1.38).
Conclusions
During the COVID-19 pandemic, non-medical personnel tended to have higher odds of being categorized as having PTSD. Workers with prior MERS-CoV experience were more susceptible than those without such experience. These findings suggest the need for timely interventions to manage human resources for a sustainable quarantine system.
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Summary
Korean summary
본 연구는 COVID-19관련 인식과 COVID-19 안심 병원 근로자들의 외상 후 스트레스 장애 (PTSD) 유병률 사이의 연관성에서 직업 유형과 이전 중동 호흡기 증후군 (MERS-CoV) 방역 경험 여부로 인한 연관성의 크기 차이를 조사하였다. 비의료인이 의료인보다 PTSD유병에 더 강한 연관성을 보였고, 이전 메르스 방역 경험이 있는 근로자들이 COVID-19에 대한 "일반적 공포", "물품 부족 공포" 및 "특정 문제에 따른 공포"로 구분한 인식의 크기가 클 수록 방역 경험이 없는 근로자들보다 PTSD유병과의 관련성이 더 컸다. 결론적으로 COVID-19 대유행 기간 중 비의료 인력은 PTSD유병 확률이 더 높은 경향이 있었다. 이전 MERS-CoV 경험이 있는 근로자는 그러한 경험이 없는 근로자보다 더 취약했다.
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Citations
Citations to this article as recorded by

- Prevalence of post-traumatic stress disorder in healthcare workers before and during COVID-19: a systematic review and meta-analysis
Claire Frodsham, Samuel B. Harvey, Daniel Collins, Karen Krakue, Vita Ligaya Dalgaard, Rosie Lipscomb, Matthew Hotopf, Mark Deady, Richard Bryant, Aimee Gayed
Frontiers in Public Health.2026;[Epub] CrossRef - Perception of response governance and collaborative attitude of hospital infection outbreak and their association with perceived stress among healthcare workers: a cross-sectional study in North-Eastern China
Weixin Zhang, Cunling Yan, Man Li, Bingyan Yu, Longfei Ma, Jiaqing Xiao, Ning Ning
BMJ Open.2026; 16(8): e120080. CrossRef - Prevalence of post-traumatic stress disorder in Peruvian military: a cross-sectional study
Mario J. Valladares-Garrido, Cinthia Karina Picón-Reátegui, J. Pierre Zila-Velasque, Virgilio E. Failoc-Rojas, César Johan Pereira Victorio, Danai Valladares-Garrido, Víctor J. Vera-Ponce
Frontiers in Psychiatry.2025;[Epub] CrossRef - Association between social networks and symptoms of post-traumatic stress during the pandemic: Cohort study in South Korea
Ji Su Yang, Yu Jin Lee, Hyeon Chang Kim, Chul-Hyun Cho, Alexander C. Tsai, Sun Jae Jung
Comprehensive Psychiatry.2023; 127: 152432. CrossRef - Development and Validation of COVID-19 Stress Scale (CSS) in an Iranian Non-clinical Population
Roghieh Nooripour, Nikzad Ghanbari, Laurel E. Radwin, Simin Hosseinian, Peyman Hassani-Abharian, Mohsen Hosseinbor, Keyvan Kakabraee, Mojtaba Amiri Majd, Serge Brand, Esmaeil Soleimani, Hossein Ilanloo
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Original Article
- Perceived Discrimination, Depression, and the Role of Perceived Social Support as an Effect Modifier in Korean Young Adults
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Kwanghyun Kim, Sun Jae Jung, So Mi Jemma Cho, Ji Hye Park, Hyeon Chang Kim
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J Prev Med Public Health. 2019;52(6):366-376. Published online October 24, 2019
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DOI: https://doi.org/10.3961/jpmph.19.114
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12,417
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206
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13
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Abstract
Summary
PDF
Supplementary Material
- Objectives
The relationships among discrimination, social support, and mental health have mostly been studied in minorities, and relevant studies in the general population are lacking. We aimed to investigate associations between discrimination and depressive symptoms in Korean non-minority young adults, considering the role of social support.
Methods
In total, 372 participants who completed the psychological examinations conducted in the third wave of the Jangseong High School Cohort study were included. We used the Everyday Discrimination Scale to evaluate perceived discrimination and the Beck Depression Inventory-II to measure depressive symptoms. Social support was measured by the Multidimensional Scale of Perceived Social Support. Multivariate linear regression was conducted to investigate associations between discrimination and depression, along with the effect modification of social support. We stratified the population by gender to investigate gender differences.
Results
Perceived discrimination was significantly associated with depressive symptoms (β=0.736, p<0.001), and social support was negatively associated with depression (β=-0.245, p<0.001). In men, support from friends was the most influential factor (β=-0.631, p=0.011), but no significant effect modification was found. In women, support from family was the most influential factor (β=-0.440, p=0.010), and women with higher familial support showed a significantly diminished association between discrimination and depression, unlike those with lower family support.
Conclusions
Discrimination perceived by individuals can lead to depressive symptoms in Korean young adults, and this relationship can may differ by gender and social support status.
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Summary
Korean summary
본 연구에서는 한국인에서 차별이 우울 증상에 미치는 영향을 평가하고 사회적 지지가 차별의 건강영향을 조절하는지 확인하고자 하였다. 인지된 차별은 우울 증상과 양의 상관관계를 보였으며, 높은 사회적 지지는 차별의 부정적 건강 영향을 경감시키는 효과를 보였다. 남성에서는 친구로부터의 사회적 지지가 가장 강한 영향력을 나타냈으며, 여성에서는 가족으로부터의 사회적 지지가 가장 강한 효과를 보였다.
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Citations
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