Key Message
This study investigated mental health symptoms among medical students after being involved in combating COVID-19 in Vietnam. Out of 580 participants, depression, anxiety, and stress rates were 43.3%, 44.0%, and 24.7%, respectively. Factors significantly associated with self-reported depression and anxiety were being female and having a COVID-19 infection. Factors associated with self-reported stress included being female, having a personal or family history of mental health symptoms, working more than 8 hours per day, and having a COVID-19 infection. The study emphasizes the importance of providing psychological support for medical students and the necessity for training programs to enhance crisis management skills.