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Original Article
- Excess Deaths During the COVID-19 Pandemic in Southern Iran: Estimating the Absolute Count and Relative Risk Using Ecological Data
- Mohammadreza Zakeri, Alireza Mirahmadizadeh, Habibollah Azarbakhsh, Seyed Sina Dehghani, Maryam Janfada, Mohammad Javad Moradian, Leila Moftakhar, Mehdi Sharafi, Alireza Heiran
- J Prev Med Public Health. 2024;57(2):120-127. Published online February 7, 2024
- DOI: https://doi.org/10.3961/jpmph.23.198
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- 303 Download
- 4 Web of Science
- 3 Crossref
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Abstract
Summary
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Supplementary Material - Objectives
The coronavirus disease 2019 (COVID-19) pandemic led to increased mortality rates. To assess this impact, this ecological study aimed to estimate the excess death counts in southern Iran.
Methods
The study obtained weekly death counts by linking the National Death Registry and Medical Care Monitoring Center repositories. The P-score was initially estimated using a simple method that involved calculating the difference between the observed and expected death counts. The interrupted time series analysis was then used to calculate the mean relative risk (RR) of death during the first year of the pandemic.
Results
Our study found that there were 5571 excess deaths from all causes (P-score=33.29%) during the first year of the COVID-19 pandemic, with 48.03% of these deaths directly related to COVID-19. The pandemic was found to increase the risk of death from all causes (RR, 1.26; 95% confidence interval [CI], 1.19 to 1.33), as well as in specific age groups such as those aged 35-49 (RR, 1.21; 95% CI, 1.12 to 1.32), 50-64 (RR, 1.38; 95% CI, 1.28 to 1.49), and ≥65 (RR, 1.29; 95% CI, 1.12 to 1.32) years old. Furthermore, there was an increased risk of death from cardiovascular diseases (RR, 1.17; 95% CI, 1.11 to 1.22).
Conclusions
There was a 26% increase in the death count in southern Iran during the COVID-19 pandemic. More than half of these excess deaths were not directly related to COVID-19, but rather other causes, with cardiovascular diseases being a major contributor. -
SummaryKey Message
During the first year of the COVID-19 pandemic in southern Iran, there was a notable increase in excess deaths, representing a 33.29% rise compared to expected figures. Approximately half of these excess deaths were directly attributed to COVID-19. Moreover, the pandemic heightened the risk of death across all causes by 26%, with specific age groups, notably those aged 50-64, experiencing heightened vulnerability. Notably, cardiovascular diseases emerged as a significant contributor to excess mortality during this period, while decreases were observed in deaths related to chronic respiratory diseases and cancers.Citations
Citations to this article as recorded by
- High incidence of post-discharge cardiovascular mortality after COVID-19 hospitalization: a data-linkage study in Southern Iran
Alireza Heiran, Amir Askarinejad, Sarvin Sasannia, Mana Moghadami, Foozhan Vaziri, Armin Naderi, Amirhossein Akbari Dahuee, Aida Bazrgar, Mahnaz Jafari, Leila Jamali, Mohammad Keshavarz, Fateme Hooman, Arash Shekari, Mahboubeh Aliakbarian Haveshki, Omid K
BMC Cardiovascular Disorders.2026;[Epub] CrossRef - Utilization of Acid Suppressants After Withdrawal of Ranitidine in Korea: An Interrupted Time Series Analysis
Jeong Pil Choi, Sangwan Kim, Jung Su Park, Mi-Sook Kim, Nam-Kyong Choi, Cheol Min Shin, Joongyub Lee
Journal of Preventive Medicine and Public Health.2025; 58(1): 21. CrossRef - Lived experiences of COVID-19 survivors admitted to the respiratory intensive care unit (RICU): phenomenological study in Southern Iran
Esmaeil Barkhori Mehni, Foozieh Rafati, Mohsen Abbasi, Shideh Rafati, Sudabeh Ahmadidarrehsima
BMC Psychology.2025;[Epub] CrossRef
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