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Young Woo Jin 3 Articles
The Association Between Apolipoprotein E Genotype and Lipid Profiles in Healthy Woman Workers.
Kieun Moon, Sook Hee Sung, Youn Koun Chang, Il Keun Park, Yun Mi Paek, Soo Geun Kim, Tae In Choi, Young Woo Jin
J Prev Med Public Health. 2010;43(3):213-221.
DOI: https://doi.org/10.3961/jpmph.2010.43.3.213
  • 5,147 View
  • 58 Download
  • 10 Crossref
AbstractAbstract PDF
OBJECTIVES
Plasma lipid profiles and Apolipoprotein E (ApoE) are established risk factors for cardiovascular disease (CVD). The knowledge of lipid profile may estimate the potential victims of cardiovascular disease before its initiation and progression and offers the opportunity for primary prevention. The most common ApoE polymorphism has been found to influence plasma lipid concentrations and its correlation with CVD has been extensively investigated in the last decade. METHODS: The ApoE polymorphism and its influence on plasma lipid were investigated in healthy woman workers. The information on confounding factors was obtained through a self-administered questionnaire and ApoE polymorphism was investigated using PCR. RESULTS: The relative frequencies of alleles E2, E3 and E4 for the study population (n=305) were 0.127, 0.750 and 0.121, respectively. ApoE polymorphism was associated with variations in plasma HDL-cholesterol lipid profile. In order to estimate the independent effects of alleles E2 and E4, as compared with E3, on lipid profile, multiple regression was performed after adjustment for confounding variables such as age, BMI, blood pressure, education status, insulin, fasting glucose, HOMA-IR, menopause. ApoE2 had a negative association with HDL cholesterol and ApoE4 had a positive association with LDL cholesterol. CONCLUSIONS: This study identified that the ApoE and CVD risk factors contribute to the lipid profiles, similar to other studies. The analysis including dietary intake and other gene in further studies may help to identify clear effects on lipid profiles as risk factor for CVD.
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Citations

Citations to this article as recorded by  
  • Visceral Adiposity Index and Lipid Accumulation Product as Effective Markers of Different Obesity Phenotypes in Korean Adults: A Cross-Sectional Analysis
    Sung Ryul Yu, Kyung-A Shin
    Diabetes, Metabolic Syndrome and Obesity.2023; Volume 16: 495.     CrossRef
  • Association between Hypertriglyceridemic-Waist Phenotype and Metabolic Abnormalities in Hypertensive Adults
    Kyung-A SHIN, Myung Shin KANG
    Korean Journal of Clinical Laboratory Science.2023; 55(2): 113.     CrossRef
  • Association Between Four Anthropometric Indexes and Metabolic Syndrome in US Adults
    Yaling Li, Rui Zheng, Shuting Li, Ruyi Cai, Feihua Ni, Huiyan Zheng, Ruying Hu, Ting Sun
    Frontiers in Endocrinology.2022;[Epub]     CrossRef
  • Shared genetic risk factors for depression and stroke
    Fuying Zhao, Yingying Yue, Haitang Jiang, Yonggui Yuan
    Progress in Neuro-Psychopharmacology and Biological Psychiatry.2019; 93: 55.     CrossRef
  • Assessing a Body Shape Index and Waist to Height Ratio as a Risk Predictor for Insulin Resistance and Metabolic Syndrome among Korean Adults
    Kyung-A Shin
    The Korean Journal of Clinical Laboratory Science.2018; 50(1): 44.     CrossRef
  • Clinical Usefulness of Serum Uric Acid and Resting Heart Rate in the Diagnosis of Metabolic Syndrome in Korean Adults
    Kyung-A Shin
    Biomedical Science Letters.2017; 23(2): 118.     CrossRef
  • The Association of Pulse Pressure and Pre-Metabolic Syndrome in Korean Middle Aged Men
    Kyung-A Shin
    Biomedical Science Letters.2017; 23(2): 73.     CrossRef
  • The Clinical Implications of Hepatic Enzymes in Metabolically Healthy Obese Men
    Kyung-A Shin
    The Korean Journal of Clinical Laboratory Science.2017; 49(3): 248.     CrossRef
  • Relationship between the Lipid Accumulation Product Index and Alanine Aminotransferase in Korean Adult Men
    Kyung-A Shin
    The Korean Journal of Clinical Laboratory Science.2017; 49(4): 374.     CrossRef
  • The Differences of Metabolic Syndrome Risk Factors according to Obesity and Abdominal Obesity in Elderly Korean Women
    Kyung-A Shin
    The Korean Journal of Clinical Laboratory Science.2016; 48(4): 304.     CrossRef
Radiation Exposure and Cancer Mortality Among Nuclear Power Plant Workers: a Meta-analysis.
Eun Sook Park, Kieun Moon, Han Na Kim, Won Jin Lee, Young Woo Jin
J Prev Med Public Health. 2010;43(2):185-192.
DOI: https://doi.org/10.3961/jpmph.2010.43.2.185
  • 5,901 View
  • 287 Download
  • 4 Crossref
AbstractAbstract PDF
OBJECTIVES
We conducted a meta-analysis to investigate the relationship between low external doses of ionizing radiation exposure and the risk of cancer mortality among nuclear power plant workers. METHODS: We searched MEDLINE using key words related to low dose and cancer risk. The selected articles were restricted to those written in English from 1990 to January 2009. We excluded those studies with no fit to the selection criteria and we included the cited references in published articles to minimize publication bias. Through this process, a total of 11 epidemiologic studies were finally included. RESULTS: We found significant decreased deaths from all cancers (SMR = 0.75, 95% CI = 0.62 - 0.90), all cancers excluding leukemia, solid cancer, mouth and pharynx, esophagus, stomach, rectum, liver and gallbladder, pancreas, lung, prostate, lymphopoietic and hematopoitic cancer. The findings of this meta-analysis were similar with those of the 15 Country Collaborative Study conducted by the International Agency for Research on Cancer. A publication bias was found only for liver and gallbladder cancer (p = 0.015). Heterogeneity was observed for all cancers, all cancers excluding leukemia, solid cancer, esophagus, colon and lung cancer. CONCLUSIONS: Our findings of low mortality for stomach, rectum, liver and gallbladder cancers may explained by the health worker effect. Yet further studies are needed to clarify the low SMR of cancers, for which there is no useful screening tool, in nuclear power plant workers.
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Citations

Citations to this article as recorded by  
  • Average Accumulated Radiation Doses for Global Nuclear Workers: Low Doses, Low Effects, and Comparison with Doses for Medical Radiologists
    A. N. Koterov, A. R. Tukov, L. N. Ushenkova, M. V. Kalinina, A. P. Biryukov
    Biology Bulletin.2022; 49(12): 2475.     CrossRef
  • Fiber-optic humidity sensor system for the monitoring and detection of coolant leakage in nuclear power plants
    Hye Jin Kim, Hyun Young Shin, Cheol Ho Pyeon, Sin Kim, Bongsoo Lee
    Nuclear Engineering and Technology.2020; 52(8): 1689.     CrossRef
  • Occupational Risk Factors for Prostate Cancer: A Meta-analysis
    Srmena Krstev, Anders Knutsson
    Journal of Cancer Prevention.2019; 24(2): 91.     CrossRef
  • An Update on Occupation and Prostate Cancer
    Glenn Doolan, Geza Benke, Graham Giles
    Asian Pacific Journal of Cancer Prevention.2014; 15(2): 501.     CrossRef
Change on Lens Accomodation and Pupil Light Reflex in VDT works.
Euna Kim, Yang Ho Kim, Young Woo Jin, Chang Ho Chai, Yong Hyu Choi, Young Hahan Moon
Korean J Prev Med. 1997;30(3):599-608.
  • 2,129 View
  • 26 Download
AbstractAbstract PDF
We studied on change of lens accommodation and pupil light reflex caused by VDT work in six women and compared them with those of other office works. The results were as follows. 1. In VDT work group, the accommodation contraction velocity decreased during the first 2-hr VDT task, then recovered markedly by the end of the one-hour lunch break, and then decreased again by the end of the 2nd 2-hr VDT task. Changes of relaxation velocity showed similar pattern although it was less typical than that of contraction velocity. 2. There was no marked change in accommodation contraction velocity and amplitude of accommodation in general office work group and near-distance office work group, and in the near-distance office work accommodation relaxation velocity decreased according to work load without recovery after lunch break. 3. Initial pupil diameter, initial pupil area of light reflex decreased significantly during VDT task only in VDT work group, and didn't recover after lunch break. These results suggest possibility that changes of accommodation contraction velocity, accommodation relaxation velocity, near point distance, and pupil diameter and area are useful in evaluating characteristics of VDT work. For this, more research adjusted individual differences, circadian rhythm, emotional stress needs.
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