- The Effect of Breastfeeding Duration and Parity on the Risk of Epithelial Ovarian Cancer: A Systematic Review and Meta-analysis
-
Ho Kyung Sung, Seung Hyun Ma, Ji-Yeob Choi, Yunji Hwang, Choonghyun Ahn, Byoung-Gie Kim, Yong-Man Kim, Jae Weon Kim, Sokbom Kang, Jaehoon Kim, Tae Jin Kim, Keun-Young Yoo, Daehee Kang, Suekyung Park
-
J Prev Med Public Health. 2016;49(6):349-366. Published online September 8, 2016
-
DOI: https://doi.org/10.3961/jpmph.16.066
-
-
15,588
View
-
302
Download
-
52
Crossref
-
Abstract
PDFSupplementary Material
- Objectives
We conducted a systematic review and meta-analysis to summarize current evidence regarding the association of parity and duration of breastfeeding with the risk of epithelial ovarian cancer (EOC).
Methods A systematic search of relevant studies published by December 31, 2015 was performed in PubMed and EMBASE. A random-effect model was used to obtain the summary relative risks (RRs) and 95% confidence intervals (CIs).
Results Thirty-two studies had parity categories of 1, 2, and ≥3. The summary RRs for EOC were 0.72 (95% CI, 0.65 to 0.79), 0.57 (95% CI, 0.49 to 0.65), and 0.46 (95% CI, 0.41 to 0.52), respectively. Small to moderate heterogeneity was observed for one birth (p<0.01; Q=59.46; I2=47.9%). Fifteen studies had breastfeeding categories of <6 months, 6-12 months, and >13 months. The summary RRs were 0.79 (95% CI, 0.72 to 0.87), 0.72 (95% CI, 0.64 to 0.81), and 0.67 (95% CI, 0.56 to 0.79), respectively. Only small heterogeneity was observed for <6 months of breastfeeding (p=0.17; Q=18.79, I2=25.5%). Compared to nulliparous women with no history of breastfeeding, the joint effects of two births and <6 months of breastfeeding resulted in a 0.5-fold reduced risk for EOC.
Conclusions The first birth and breastfeeding for <6 months were associated with significant reductions in EOC risk.
-
Summary
-
Citations
Citations to this article as recorded by
- Pelvic inflammatory disease and risk of epithelial ovarian cancer: a national population-based case-control study in Sweden
Sarah Jonsson, Håkan Jonsson, Eva Lundin, Christel Häggström, Annika Idahl American Journal of Obstetrics and Gynecology.2024; 230(1): 75.e1. CrossRef - Agricultural exposure and risk of ovarian cancer in the AGRIculture and CANcer (AGRICAN) cohort
Marine Renier, Juliette Hippert, Louis-Bastien Weiswald, Séverine Tual, Matthieu Meryet-Figuiere, Nicolas Vigneron, Elisabeth Marcotullio, Isabelle Baldi, Pierre Lebailly Occupational and Environmental Medicine.2024; 81(2): 75. CrossRef - Prenatal Counseling on the Maternal Health Benefits of Lactation: A Randomized Trial
Eleanor B. Schwarz, Adrienne Hoyt-Austin, Margaret Fix, Laura R. Kair, Caidon Iwuagwu, Melissa J. Chen Breastfeeding Medicine.2024; 19(1): 52. CrossRef - Awareness of the Maternal Health Benefits of Lactation Among U.S. Pregnant Individuals
Caidon Iwuagwu, Melissa J. Chen, Adrienne E. Hoyt-Austin, Laura Kair, Margaret Fix, Eleanor Bimla Schwarz Women's Health Issues.2024; 34(3): 283. CrossRef - Breastfeeding’s protective role in alleviating breast cancer burden: A comprehensive review
Emmanuel Ifeanyi Obeagu, Getrude Uzoma Obeagu Annals of Medicine & Surgery.2024;[Epub] CrossRef - Fraction of cancers attributable to and prevented by reproductive factors and exogenous hormones use in Italy
Federica Turati, Giulia Collatuzzo, Matteo Di Maso, Eva Negri, Giovanna Esposito, Gianfranco Alicandro, Matteo Malvezzi, Claudio Pelucchi, Paolo Boffetta, Carlo La Vecchia, Fabio Parazzini European Journal of Obstetrics & Gynecology and Reproductive Biology.2024; 301: 49. CrossRef - A dose–response meta-analysis of the relationship between number of pregnancies and risk of gynecological cancers
Jalal Poorolajal, Amin Doosti-Irani, Ali Mohammad Karami, Marzieh Fattahi-Darghlou Archives of Gynecology and Obstetrics.2024;[Epub] CrossRef - Ovulation induction drug and ovarian cancer: an updated systematic review and meta-analysis
Liang Yu, Jiafan Sun, Qiqin Wang, Wennian Yu, Anqi Wang, Shu Zhu, Wei Xu, Xiuli Wang Journal of Ovarian Research.2023;[Epub] CrossRef - La Salpingo-oforectomía o Salpingectomía como estrategia para prevenir el cáncer de ovario
Scarlet Hochstatter Irarrázabal, Erwin Hochstatter Arduz Revista Medica.2023; 27(1): 26. CrossRef - Stratifying the risk of ovarian cancer incidence by histologic subtypes in the Korean Epithelial Ovarian Cancer Study (Ko‐EVE)
Soseul Sung, Youjin Hong, Byoung‐Gie Kim, Ji‐Yeob Choi, Jae Weon Kim, Sang‐Yoon Park, Jae‐Hoon Kim, Yong‐man Kim, Jong‐Min Lee, Tae Jin Kim, Sue K. Park Cancer Medicine.2023; 12(7): 8742. CrossRef - Abortion and Female Cancer Risks among Women Aged 20 to 45 Years: A 10-Year Longitudinal Population-Based Cohort Study in Taiwan
Cheng-Ting Shen, Shu-Yu Tai, Yu-Hsiang Tsao, Fang-Ming Chen, Hui-Min Hsieh International Journal of Environmental Research and Public Health.2023; 20(4): 3682. CrossRef - Lifetime ovulatory years and risk of epithelial ovarian cancer: a multinational pooled analysis
Zhuxuan Fu, Maria Mori Brooks, Sarah Irvin, Susan Jordan, Katja K H Aben, Hoda Anton-Culver, Elisa V Bandera, Matthias W Beckmann, Andrew Berchuck, Angela Brooks-Wilson, Jenny Chang-Claude, Linda S Cook, Daniel W Cramer, Kara L Cushing-Haugen, Jennifer A JNCI: Journal of the National Cancer Institute.2023; 115(5): 539. CrossRef - Role of breastfeeding on maternal and childhood cancers: An umbrella review of meta-analyses
Dazhi Fan, Qing Xia, Dongxin Lin, Yubo Ma, Jiaming Rao, Li Liu, Hai Tang, Tingting Xu, Pengsheng Li, Gengdong Chen, Zixing Zhou, Xiaoling Guo, Zhifang Zhang, Zhengping Liu Journal of Global Health.2023;[Epub] CrossRef - What does a doctor need to know about breastfeeding and adolescent health and pregnancy?
Leandro Meirelles Nunes, Rossiclei de Souza Pinheiro, Izailza Matos Dantas Lopes, Darci Vieira da Silva Bonetto, Alda Elizabeth Boehler Iglesias Azevedo Revista da Associação Médica Brasileira.2023;[Epub] CrossRef - Deficiencies in the Intentions, Attitudes, and Knowledge of Future Healthcare Professionals Regarding Breastfeeding
Marija Čatipović, Štefica Mikšić, Rajko Fureš, Zrinka Puharić, Dragica Pavlović Children.2023; 10(7): 1256. CrossRef - Examining psychometric properties of the Iranian version of exclusive breastfeeding social support scale (EBFSS)
Sepideh Mashayekh-Amiri, Mina Hosseinzadeh, Mohammad Asghari Jafarabadi, Sepideh Soltani, Mojgan Mirghafourvand BMC Psychology.2023;[Epub] CrossRef - Are pregnancy and parity associated with telomere length? A systematic review
Nourit Houminer-Klepar, Shiran Bord, Elissa Epel, Orna Baron-Epel BMC Pregnancy and Childbirth.2023;[Epub] CrossRef - Global patterns and temporal trends in ovarian cancer morbidity, mortality, and burden from 1990 to 2019
Afrooz Mazidimoradi, Zohre Momenimovahed, Yousef Khani, Armin Rezaei Shahrabi, Leila Allahqoli, Hamid Salehiniya Oncologie.2023; 25(6): 641. CrossRef - Pregnancy, preeclampsia and maternal aging: From epidemiology to functional genomics
Eliza C. Miller, Ashley Wilczek, Natalie A. Bello, Sarah Tom, Ronald Wapner, Yousin Suh Ageing Research Reviews.2022; 73: 101535. CrossRef - Lifetime ovulations and epithelial ovarian cancer risk and survival: A systematic review and meta-analysis
Zhuxuan Fu, Sarah Taylor, Francesmary Modugno Gynecologic Oncology.2022; 165(3): 650. CrossRef - The Effects of Breastfeeding on Maternal Mental Health: A Systematic Review
Megan Yuen, Olivia J. Hall, Grace A. Masters, Benjamin C. Nephew, Catherine Carr, Katherine Leung, Adrienne Griffen, Lynne McIntyre, Nancy Byatt, Tiffany A. Moore Simas Journal of Women's Health.2022; 31(6): 787. CrossRef - Breastfeeding Among Pediatric Emergency Physicians
Marissa Hendrickson, Cynthia S. Davey, Brian A. Harvey, Kari Schneider Pediatric Emergency Care.2022; 38(7): e1372. CrossRef - A Follow-Up Study of Ovarian Cancer (OOPS): A Study Protocol
Ting-Ting Gong, Fang-Hua Liu, Ya-Shu Liu, Shi Yan, He-Li Xu, Xin-Hui He, Yi-Fan Wei, Xue Qin, Song Gao, Yu-Hong Zhao, Qi-Jun Wu Frontiers in Nutrition.2022;[Epub] CrossRef - Extraterrestrial Gynecology: Could Spaceflight Increase the Risk of Developing Cancer in Female Astronauts? An Updated Review
Rosa Drago-Ferrante, Riccardo Di Fiore, Fathi Karouia, Yashwanth Subbannayya, Saswati Das, Begum Aydogan Mathyk, Shehbeel Arif, Ana Paula Guevara-Cerdán, Allen Seylani, Aman Singh Galsinh, Weronika Kukulska, Joseph Borg, Sherif Suleiman, David Marshall Po International Journal of Molecular Sciences.2022; 23(13): 7465. CrossRef - Behaviour, Attitudes and Knowledge of Healthcare Workers on Breastfeeding
Marija Čatipović, Zrinka Puharić, Drita Puharić, Paula Čatipović, Josip Grgurić Children.2022; 9(8): 1173. CrossRef - Lactancia materna
E. Raimond, N. Leloux, R. Gabriel EMC - Ginecología-Obstetricia.2022; 58(4): 1. CrossRef - Human Milk Microbiota and Oligosaccharides: A Glimpse into Benefits, Diversity, and Correlations
Carole Ayoub Moubareck Nutrients.2021; 13(4): 1123. CrossRef - Couples talk about breastfeeding: Interviews with parents about decision-making, challenges, and the role of fathers and professional support
Erin J Henshaw, Maria Mayer, Sarina Balraj, Elsie Parmar, Kristine Durkin, Rita Snell Health Psychology Open.2021;[Epub] CrossRef - Influence of lactation and nutrition on health of nursing woman
S. V. Orlova, E. A. Nikitina, A. N. Vodolazkaya, L. Yu. Volkova, E. V. Prokopenko Medical alphabet.2021; (21): 75. CrossRef - Supporting Exclusive Breastfeeding Among Factory Workers and Their Unemployed Neighbors: Peer Counseling in Bangladesh
Rukhsana Haider, Virginia Thorley Journal of Human Lactation.2020; 36(3): 414. CrossRef - The Ketogenic Diet Including Breast Milk for Treatment of Infants with Severe Childhood Epilepsy: Feasibility, Safety, and Effectiveness
Anastasia Dressler, Chiara Häfele, Vito Giordano, Franz Benninger, Petra Trimmel-Schwahofer, Gudrun Gröppel, Sharon Samueli, Martha Feucht, Christoph Male, Andreas Repa Breastfeeding Medicine.2020; 15(2): 72. CrossRef - Gender of offspring and risk of ovarian cancer: The HOPE study
Zhuxuan Fu, Kirsten Moysich, Roberta B. Ness, Francesmary Modugno Cancer Epidemiology.2020; 64: 101646. CrossRef - Ovarian cancer screening: Current status and future directions
Zachary Nash, Usha Menon Best Practice & Research Clinical Obstetrics & Gynaecology.2020; 65: 32. CrossRef - “I was determined to breastfeed, and I always found a solution”: successful experiences of exclusive breastfeeding among Chinese mothers in Ireland
Qianling Zhou, Haoyue Chen, Katherine M. Younger, Tanya M. Cassidy, John M. Kearney International Breastfeeding Journal.2020;[Epub] CrossRef - An Update on Screening and Prevention for Breast and Gynecological Cancers in Average and High Risk Individuals
Anahid M Pahlawanian, Vanessa A Norris, Amelia M Jernigan, Brooke Morrell, Mignonne Morrell, Navya Nair, Amber M Karamanis, Erin M Dauchy, Michelle M Loch, Agustin A Garcia The American Journal of the Medical Sciences.2020; 360(5): 489. CrossRef - Association of Social and Community Factors with U.S. Breastfeeding Outcomes
Leslie Kummer, Naomi Duke, Laurel Davis, Iris Borowsky Breastfeeding Medicine.2020; 15(10): 646. CrossRef - Breastfeeding Among Mothers Who Have Experienced Childhood Maltreatment: A Review
Amara Channell Doig, Michelle Jasczynski, Jamie L. Fleishman, Elizabeth M. Aparicio Journal of Human Lactation.2020; 36(4): 710. CrossRef - Offspring sex and risk of epithelial ovarian cancer: a multinational pooled analysis of 12 case–control studies
Francesmary Modugno, Zhuxuan Fu, Susan J. Jordan, AOCS Group, Jenny Chang-Claude, Renée T. Fortner, Marc T. Goodman, Kirsten B. Moysich, Joellen M. Schildkraut, Andrew Berchuck, Elisa V. Bandera, Bo Qin, Rebecca Sutphen, John R. McLaughlin, Usha Menon, Su European Journal of Epidemiology.2020; 35(11): 1025. CrossRef - Translational Theragnosis of Ovarian Cancer: where do we stand?
Maria Grazia Perrone, Oreste Luisi, Anna De Grassi, Savina Ferorelli, Gennaro Cormio, Antonio Scilimati Current Medicinal Chemistry.2020; 27(34): 5675. CrossRef - Breastfeeding factors and risk of epithelial ovarian cancer
Francesmary Modugno, Sharon L. Goughnour, Danielle Wallack, Robert P. Edwards, Kunle Odunsi, Joseph L. Kelley, Kirsten Moysich, Roberta B. Ness, Maria Mori Brooks Gynecologic Oncology.2019; 153(1): 116. CrossRef - Flexible piecewise linear model for investigating dose‐response relationship in meta‐analysis: Methodology, examples, and comparison
Chang Xu, Lehana Thabane, Tongzu Liu, ASM Borhan, Xin Sun Journal of Evidence-Based Medicine.2019; 12(1): 63. CrossRef - Critical questions in ovarian cancer research and treatment: Report of an American Association for Cancer Research Special Conference
Robert C. Bast, Ursula A. Matulonis, Anil K. Sood, Ahmed A. Ahmed, Adaobi E. Amobi, Frances R. Balkwill, Monicka Wielgos‐Bonvallet, David D. L. Bowtell, James D. Brenton, Joan S. Brugge, Robert L. Coleman, Giulio F. Draetta, Kai Doberstein, Ronny I. Drapk Cancer.2019; 125(12): 1963. CrossRef - Novel Approaches to Ovarian Cancer Screening
Denise R. Nebgen, Karen H. Lu, Robert C. Bast Current Oncology Reports.2019;[Epub] CrossRef - Age at last birth and risk of developing epithelial ovarian cancer: a meta-analysis
Yanjun Wu, Wenjun Sun, Xueling Xin, Weijing Wang, Dongfeng Zhang Bioscience Reports.2019;[Epub] CrossRef - The impact of historical breastfeeding practices on the incidence of cancer in France in 2015
Kevin D. Shield, Laure Dossus, Agnès Fournier, Claire Marant Micallef, Sabina Rinaldi, Agnès Rogel, Isabelle Heard, Sophie Pilleron, Freddie Bray, Isabelle Soerjomataram Cancer Causes & Control.2018; 29(3): 325. CrossRef - The role of pregnancy, perinatal factors and hormones in maternal cancer risk: a review of the evidence
R. Troisi, T. Bjørge, M. Gissler, T. Grotmol, C. M. Kitahara, S. M. Myrtveit Sæther, A. G. Ording, C. Sköld, H. T. Sørensen, B. Trabert, I. Glimelius Journal of Internal Medicine.2018; 283(5): 430. CrossRef - Ovarian Cancer Prevention and Screening
Usha Menon, Chloe Karpinskyj, Aleksandra Gentry-Maharaj Obstetrics & Gynecology.2018; 131(5): 909. CrossRef - Breastfeeding experience, challenges and service demands among Chinese mothers: A qualitative study in two cities
Yan Zhang, Yi Jin, Carel Vereijken, Bernd Stahl, Hong Jiang Appetite.2018; 128: 263. CrossRef - Postpartum Cardiomyopathy and Considerations for Breastfeeding
Laura Kearney, Paul Wright, Sadeer Fhadil, Martin Thomas Cardiac Failure Review.2018; 4(2): 112. CrossRef - Breastfeeding and the Benefits of Lactation for Women's Health
Luiz Antonio Del Ciampo, Ieda Regina Lopes Del Ciampo Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics.2018; 40(06): 354. CrossRef - Ovarian Cancer Prevention in High-risk Women
SARAH M. TEMKIN, JENNIFER BERGSTROM, GOLI SAMIMI, LORI MINASIAN Clinical Obstetrics & Gynecology.2017; 60(4): 738. CrossRef - Risk Reduction of Breast Cancer by Childbirth,
Breastfeeding, and Their Interaction in Korean Women: Heterogeneous Effects Across Menopausal Status, Hormone Receptor Status, and Pathological Subtypes
Seok Hun Jeong, Yoon Suk An, Ji-Yeob Choi, Boyoung Park, Daehee Kang, Min Hyuk Lee, Wonshik Han, Dong Young Noh, Keun-Young Yoo, Sue K. Park Journal of Preventive Medicine and Public Health.2017; 50(6): 401. CrossRef
|