Skip Navigation
Skip to contents

JPMPH : Journal of Preventive Medicine and Public Health


Author index

Page Path
HOME > Browse Articles > Author index
Kyoo Duck Lee 1 Article
Association Between Prophylactic Antibiotic Use and Surgical Site Infection Based on Quality Assessment Data in Korea.
Kyoung Hoon Kim, Choon Seon Park, Jin Hee Chang, Nam Soon Kim, Jin Seo Lee, Bo Ram Choi, Byung Ran Lee, Kyoo Duck Lee, Sun Min Kim, Seon A Yeom
J Prev Med Public Health. 2010;43(3):235-244.
  • 5,603 View
  • 84 Download
  • 10 Crossref
AbstractAbstract PDF
To examine the prophylactic antibiotic use in reducing surgical site infection. METHODS: This was a retrospective study for patients aged 18 years and older who underwent gastrectomy, cholecystectomy, colectomy, cesarean section and hysterectomy. The data source was quality assessment data of the Health Insurance Review & Assessment Service gathered from medical records of 302 national hospitals. Prophylactic antibiotic use was defined as: timely antibiotic administration or inappropriate antibiotic selection. We performed hierarchical logistic regression to examine the association between prophylactic antibiotic use and surgical site infection with adjustment for covariates. RESULTS: The study population consisted of 16 348 patients (1588 gastrectomies, 2327 cholecystectomies, 1,384 colectomies, 3977 hysterectomies and 7072 cesarean sections) and surgical site infection was identified in 351 (2.1%) patients. The rates of timely antibiotic administration and inappropriate antibiotic selection varied according to procedures. Cholecystectomy patients who received timely prophylactic antibiotic had a significantly reduced risk of surgical site infection compared with those who did not receive a timely prophylactic antibiotics (OR 0.64, 95% CI=0.50-0.83), but no significant reduction was observed for other procedures. When inappropriate prophylactic antibiotics were given, the risk of surgical site infection significantly increased: 8.26-fold (95% CI=4.34-15.7) for gastrectomy, 4.73-fold (95% CI=2.09-10.7) for colectomy, 2.34-fold (95% CI=1.14-4.80) for cesarean section, 4.03-fold (95% CI=1.93-8.42) for hysterectomy. CONCLUSIONS: This study examines the association among timely antibiotic administration, inappropriate antibiotic selection and surgical site infection. Patients who received timely and appropriate antibiotics had a decreased risk of surgical site infection. Efforts to improve the timing of antibiotic administration and use of appropriate antibiotic are needed to lower the risk of surgical site infection.


Citations to this article as recorded by  
  • The effect of first- and third-generation prophylactic antibiotics on hospitalization and medical expenditures for cardiac surgery
    Sung-Jin Bae, Inah Kim, Jaechul Song, Euy-Suk Chung
    Journal of Cardiothoracic Surgery.2022;[Epub]     CrossRef
  • Incidence and Risk Factors of Wound Infection in Women Who Underwent Cesarean Section in 2014 at King Abdulaziz Medical City, Jeddah
    Roaa Gadeer , Nada Y Baatiah, Nourah Alageel, Mohammed Khaled
    Cureus.2020;[Epub]     CrossRef
  • Pay-for-performance reduces healthcare spending and improves quality of care: Analysis of target and non-target obstetrics and gynecology surgeries
    Seung Ju Kim, Kyu-Tae Han, Sun Jung Kim, Eun-Cheol Park
    International Journal for Quality in Health Care.2017; 29(2): 222.     CrossRef
  • Comparing the Postoperative Complications, Hospitalization Days and Treatment Expenses Depending on the Administration of Postoperative Prophylactic Antibiotics to Hysterectomy
    Mi Young Jung, Kyung-Yeon Park
    Korean Journal of Women Health Nursing.2017; 23(1): 42.     CrossRef
  • Risk Factors for Surgical Site Infections According to Electronic Medical Records Data
    Young Hee Kim, Young-Hee Yom
    Journal of Korean Academy of Fundamentals of Nursing.2014; 21(2): 151.     CrossRef
  • Morbidity and risk factors for surgical site infection following cesarean section in Guangdong Province, China
    Shi‐Peng Gong, Hong‐Xia Guo, Hong‐Zhen Zhou, Li Chen, Yan‐Hong Yu
    Journal of Obstetrics and Gynaecology Research.2012; 38(3): 509.     CrossRef
  • Overview of Antibiotic Use in Korea
    Baek-Nam Kim
    Infection & Chemotherapy.2012; 44(4): 250.     CrossRef
  • The effect of surgical site infection on the length of stay and health care costs
    Jin-Hee Chang, Kyoung-Hoon Kim, Soon-Man Kwon, Seon-A Yeom, Choon-Seon Park
    Korean Journal of Health Policy and Administration.2011; 21(1): 44.     CrossRef
  • Risk factors for surgical site infection in children at the teaching hospital Gabriel Touré, Bamako
    A. Togo, Y. Coulibaly, B.T. Dembélé, B. Togo, M. Keita, L. Kanté, A. Traoré, I. Diakité, H. Ouologuem, G. Diallo
    Journal of Hospital Infection.2011; 79(4): 371.     CrossRef
  • The Feasibility of Short Term Prophylactic Antibiotics in Gastric Cancer Surgery
    Jun Suh Lee, Han Hong Lee, Kyo Young Song, Cho Hyun Park, Hae Myung Jeon
    Journal of Gastric Cancer.2010; 10(4): 206.     CrossRef

JPMPH : Journal of Preventive Medicine and Public Health