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Kazuo Aoki 1 Article
Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China
Xiang-Quan Xie, Kui-Cheng Zheng, Bing-Shan Wu, Tie-Hui Chen, Shan-Rong Lai, Zai-Sheng Lin, Kazuo Aoki
J Prev Med Public Health. 2014;47(5):281-287.   Published online September 12, 2014
DOI: https://doi.org/10.3961/jpmph.14.018
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AbstractAbstract PDF
Objectives
In Fujian Province, China, gastric cancer is one of the leading causes of mortality among all malignant tumors. Nanjing county and Minqing county are located in inland Fujian and have similar general demographics. However, the adjusted mortality rate of gastric cancer in Minqing was found to be much higher than that in Nanjing. We sought to explore factors associated with this increased risk of gastric cancer between the two counties. Methods: We recruited 231 and 224 residents from Nanjing and Minqing, respectively, and analyzed differences between their dietary habits, Helicobacter pylori infection rates, and concentrations of serum pepsinogen I, pepsinogen II, gastrin-17, and ratio of pepsinogen I:II. Results: Subjects in Minqing had more first-degree relatives who had been diagnosed with upper gastrointestinal tumor, more unhealthy dietary habits, a higher Helicobacter pylori positive rate, and greater proportion of abnormal serum gastrin-17 than those in Nanjing did. Conclusions: The factors that differed between these two counties might indicate that residents in Minqing have a higher risk for developing gastric cancer than those in Nanjing do.
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  • HLA‐DQB1*03 genotype and perioperative blood transfusion are not conducive to the prognosis of patients with gastric cancer
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    Journal of Clinical Laboratory Analysis.2018;[Epub]     CrossRef

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