Skip Navigation
Skip to contents

JPMPH : Journal of Preventive Medicine and Public Health


Author index

Page Path
HOME > Browse Articles > Author index
Eun-Ha Lee 1 Article
Alcohol Consumption and Mortality in the Korean Multi-center Cancer Cohort Study
En-Joo Jung, Aesun Shin, Sue K. Park, Seung-Hyun Ma, In-Seong Cho, Boyoung Park, Eun-Ha Lee, Soung-Hoon Chang, Hai-Rim Shin, Daehee Kang, Keun-Young Yoo
J Prev Med Public Health. 2012;45(5):301-308.   Published online September 28, 2012
  • 12,020 View
  • 106 Download
  • 16 Crossref
AbstractAbstract PDF

To examine the association between alcohol consumption habit, types of beverages, alcohol consumption quantity, and overall and cancer-specific mortality among Korean adults.


The alcohol consumption information of a total of 16 320 participants who were 20 years or older from the Korean Multi-center Cancer Cohort were analyzed to examine the association between alcohol consumption habit and mortality (median follow-up of 9.3 years). The Cox proportional hazard model was used to estimate the hazard ratio (HR) of alcohol consumption to mortality adjusting for age, sex, geographic areas, education, smoking status, and body mass index.


Alcohol drinkers showed an increased risk for total mortality compared with never drinkers (HR, 1.72; 95% confidence interval [CI], 1.38 to 2.14 for past drinkers; HR, 1.21; 95% CI, 1.06 to 1.39 for current drinkers), while past drinkers only were associated with higher risk for cancer deaths (HR, 1.84; 95% CI, 1.34 to 2.53). The quantity of alcohol consumed per week showed a J-shaped association with risk of mortality. Relative to light drinkers (0.01 to 90 g/wk), never drinkers and heavy drinkers (>504 g/wk) had an increased risk for all-cause and cancer deaths: (HR, 1.18; 95% CI, 0.96 to 1.45) and (HR, 1.39; 95% CI, 1.05 to 1.83) for all-cause mortality; and (HR, 1.55; 95% CI, 1.15 to 2.11) and (HR, 2.07; 95% CI, 1.39 to 3.09) for all cancer mortality, respectively. Heavy drinkers (>504 g/wk) showed an elevated risk for death from stomach and liver cancers.


The present study supports the existence of a J-shaped association between alcohol consumption quantity and the risk of all-cause and cancer deaths. Heavy drinkers had an increased risk of death from cancer overall and liver and stomach cancer.



Citations to this article as recorded by  
  • Alcohol consumption messages in Korean dramas: the globalization of South Korean drinking norms
    Rubini Pasupathy, Jaesook Gho, Brittany Duhart, Courtney Queen
    Global Health Promotion.2022; 29(3): 57.     CrossRef
  • Effect of preoperative psychiatric morbidity on postoperative outcomes of lung cancer surgery: A nationwide cohort study in South Korea
    In-Ae Song, Hye Yoon Park, Tak Kyu Oh
    Journal of Psychosomatic Research.2022; 161: 111002.     CrossRef
  • Alcohol, salud y enfermedad cardiovascular
    J. Masip, J.R. Germà Lluch
    Revista Clínica Española.2021; 221(6): 359.     CrossRef
  • Alcohol, health and cardiovascular disease
    J. Masip, J.R. Germà Lluch
    Revista Clínica Española (English Edition).2021; 221(6): 359.     CrossRef
  • Systematic Review with Meta-Analysis: Low-Level Alcohol Consumption and the Risk of Liver Cancer
    Hana Park, Seung Kak Shin, Ijin Joo, Do Seon Song, Jeong Won Jang, Joong-Won Park
    Gut and Liver.2020; 14(6): 792.     CrossRef
  • Alcohol consumption and gastric cancer risk in Korea: a case-control study
    Mi Hui Kim, Shin Ah Kim, Chan Hyuk Park, Chang Soo Eun, Dong Soo Han, Yong Sung Kim, Kyu Sang Song, Bo Youl Choi, Hyun Ja Kim
    Nutrition Research and Practice.2019; 13(5): 425.     CrossRef
  • Alcoholic Liver Disease Is Associated with an Increased Risk of Gastric Cancer
    Tae Hoon Ha, Byeong Gwan Kim, Donghyong Jeong, Sohee Oh, Won Kim, Yong Jin Jung, Dong Won Ahn, Ji Bong Jeong, Ji Won Kim, Kook Lae Lee, Seong-Joon Koh
    Digestive Diseases and Sciences.2017; 62(1): 273.     CrossRef
  • Alcohol Abuse Decreases Pelvic Control and Survival in Cervical Cancer
    Jyoti Mayadev, Chin-Shang Li, Jihoon Lim, Richard Valicenti, Edwin A. Alvarez
    American Journal of Clinical Oncology.2017; 40(5): 451.     CrossRef
  • Alcohol consumption and gastric cancer risk: a meta-analysis of prospective cohort studies
    Xue Han, Li Xiao, Yao Yu, Yu Chen, Hai-Hua Shu
    Oncotarget.2017; 8(47): 83237.     CrossRef
  • Association between alcohol consumption and the risk of gastric cancer: a meta-analysis of prospective cohort studies
    Zheng He, Ting-Ting Zhao, Hui-Mian Xu, Zhen-Ning Wang, Ying-Ying Xu, Yong-Xi Song, Zhong-Ran Ni, Hao Xu, Song-Cheng Yin, Xing-Yu Liu, Zhi-Feng Miao
    Oncotarget.2017; 8(48): 84459.     CrossRef
  • Alcohol consumption and liver cancer risk: a meta-analysis
    Shu-Chun Chuang, Yuan-Chin Amy Lee, Guo-Jie Wu, Kurt Straif, Mia Hashibe
    Cancer Causes & Control.2015; 26(9): 1205.     CrossRef
  • The relationship between mild alcohol consumption and mortality in Koreans: a systematic review and meta-analysis
    Ji-Eun Park, Tae-young Choi, Yeonhee Ryu, Sung-Il Cho
    BMC Public Health.2015;[Epub]     CrossRef
  • Association Between Alcohol Consumption and Risk of Cardiovascular Disease and All-Cause Mortality in Patients With Hypertension: A Meta-Analysis of Prospective Cohort Studies
    Chao Huang, Jian Zhan, Yu-Jian Liu, De-Jia Li, Su-Qing Wang, Qi-Qiang He
    Mayo Clinic Proceedings.2014; 89(9): 1201.     CrossRef
  • Attributable fraction of alcohol consumption on cancer using population-based nationwide cancer incidence and mortality data in the Republic of Korea
    Sohee Park, Hai-Rim Shin, Boram Lee, Aesun Shin, Kyu-Won Jung, Duk-Hee Lee, Sun Ha Jee, Sung-Il Cho, Sue Kyung Park, Mathieu Boniol, Paolo Boffetta, Elisabete Weiderpass
    BMC Cancer.2014;[Epub]     CrossRef
  • Alcohol and liver cancer: a systematic review and meta-analysis of prospective studies
    F. Turati, C. Galeone, M. Rota, C. Pelucchi, E. Negri, V. Bagnardi, G. Corrao, P. Boffetta, C. La Vecchia
    Annals of Oncology.2014; 25(8): 1526.     CrossRef
  • Alcohol Consumption and Viral Load Are Synergistically Associated with CIN1
    Kyung-Jin Min, Jae-Kwan Lee, Sanghoon Lee, Mi Kyung Kim, Rui Medeiros
    PLoS ONE.2013; 8(8): e72142.     CrossRef

JPMPH : Journal of Preventive Medicine and Public Health