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- Adjustment for Multimorbidity in Estimations of the Burden of Diseases Using Korean NHIS Data
- Yoonhee Shin, Eun Jeong Choi, Bomi Park, Hye Ah Lee, Eun-Kyung Lee, Hyesook Park
- J Prev Med Public Health. 2022;55(1):28-36. Published online January 31, 2022
- DOI: https://doi.org/10.3961/jpmph.21.583
- 3,121 View
- 111 Download
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Abstract
Summary
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Supplementary Material - The current multimorbidity correction method in the Global Burden of Disease studies assumes the independent occurrence of diseases. Those studies use Monte-Carlo simulations to adjust for the presence of multiple disease conditions for all diseases. The present study investigated whether the above-mentioned assumption is reasonable based on the prevalence confirmed from actual data. This study compared multimorbidity-adjusted years of lived with disability (YLD) obtained by Monte-Carlo simulations and multimorbidity-adjusted YLD using multimorbidity prevalence derived from National Health Insurance Service data. The 5 most common diseases by sex and age groups were selected as diseases of interest. No significant differences were found between YLD estimations made using actual data and Monte-Carlo simulations, even though assumptions about the independent occurrence of diseases should be carefully applied. The prevalence was not well reflected according to disease characteristics in those under the age of 30, among whom there was a difference in YLD between the 2 methods. Therefore, when calculating the burden of diseases for Koreans over the age of 30, it is possible to calculate the YLD with correction for multimorbidity through Monte-Carlo simulation, but care should be taken with under-30s. It is useful to apply the efficiency and suitability of calibration for multiplicative methods using Monte-Carlo simulations in research on the domestic disease burden, especially in adults in their 30s and older. Further research should be carried out on multimorbidity correction methodology according to the characteristics of multiple diseases by sex and age.
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SummaryKorean summary
질병부담 산출 시 몬테카를로 시뮬레이션을 통한 복합질환 보정 방법에 대해 다빈도 질환 실제 데이터 기반으로 검증해 봄으로써 30세 이상 연령에서 추정값에 큰 차이가 없음을 확인하였다. 하지만 30세 미만에서는 포함되는 질환 종류에 따라 실제 데이터 기반으로 복합질환을 보정하는 것이 불가능하거나 시뮬레이션으로 구한 값이 부정확하였다. 따라서, 질환 특성을 반영한 복합질환 보정방법론 개발이 필요함을 제안하며 본 연구 결과는 한국인 질병부담 연구에서 몬테카를로 시뮬레이션을 이용한 복합질환 보정 방법의 활용근거로 사용될 수 있을 것이다.
COVID-19: Original Article
- Association of Comorbidities With Pneumonia and Death Among COVID-19 Patients in Mexico: A Nationwide Cross-sectional Study
- Akram Hernández-Vásquez, Diego Azañedo, Rodrigo Vargas-Fernández, Guido Bendezu-Quispe
- J Prev Med Public Health. 2020;53(4):211-219. Published online May 28, 2020
- DOI: https://doi.org/10.3961/jpmph.20.186
- 8,321 View
- 2,336 Download
- 24 Crossref
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Abstract
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- Objectives
The goal of this study was to identify chronic conditions and multimorbidity patterns in patients with coronavirus disease 2019 (COVID-19) and to examine their associations with pneumonia and death.
Methods
This cross-sectional study analyzed the official data of COVID-19 patients in Mexico through May 18, 2020 (released by the Secretaría de Salud de México). Adjusted logistic regression models were applied to assess the associations of comorbidities with pneumonia and death. The marginal effects were estimated, and the probability of pneumonia or death according to the number of comorbidities was graphed for each year of age.
Results
Of the 51 053 COVID-19 patients enrolled in the final analysis, 27 667 (54.2%) had no chronic conditions, while 13 652 (26.7%), 6518 (12.8%) and 3216 (6.3%) were reported to have 1, 2, and 3 or more simultaneous conditions, respectively. Overall, a significant incremental gradient was observed for the association between multimorbidity and pneumonia (p<0.001); for 2 chronic conditions, the adjusted odds ratio (aOR) was 2.07 (95% confidence interval [CI], 1.95 to 2.20), and for ≥3 conditions, the aOR was 2.40 (95% CI, 2.22 to 2.60). A significant incremental gradient was also found for the relationship between multimorbidity and death (p<0.001); an aOR of 2.51 (95% CI, 2.30 to 2.73) was found for 2 chronic conditions and an aOR of 3.49 (95% CI, 3.15 to 3.86) for ≥3 conditions.
Conclusions
Underlying chronic conditions and multimorbidity are associated with pneumonia and death in Mexican COVID-19 patients. Future investigation is necessary to clarify the pathophysiological processes behind this association, given the high burden of chronic diseases in various countries, including Mexico. -
Summary
Citations
Citations to this article as recorded by
- A network-based model to assess vaccination strategies for the COVID-19 pandemic by using Bayesian optimization
Gilberto González-Parra, Javier Villanueva-Oller, F.J. Navarro-González, Josu Ceberio, Giulia Luebben
Chaos, Solitons & Fractals.2024; 181: 114695. CrossRef - Impact of COVID-19 on ‘Start Smart, Then Focus’ Antimicrobial Stewardship at One NHS Foundation Trust in England Prior to and during the Pandemic
Rasha Abdelsalam Elshenawy, Nkiruka Umaru, Zoe Aslanpour
COVID.2024; 4(1): 102. CrossRef - Multimorbidity and frailty are associated with poorer SARS-CoV-2-related outcomes: systematic review of population-based studies
Tatjana T. Makovski, Jinane Ghattas, Stéphanie Monnier-Besnard, Lisa Cavillot, Monika Ambrožová, Barbora Vašinová, Rodrigo Feteira-Santos, Peter Bezzegh, Felipe Ponce Bollmann, James Cottam, Romana Haneef, Brecht Devleesschauwer, Niko Speybroeck, Paulo Jo
Aging Clinical and Experimental Research.2024;[Epub] CrossRef - Mortalidad en adultos mexicanos de 50 a 80 años de edad con multimorbilidad en un período de observación de 18 años
Beatriz Novak, Daniel Lozano Keymolen
Estudios Demográficos y Urbanos.2023; 38(1): 9. CrossRef - Age and Comorbidities as Risk Factors for Severe COVID-19 in Mexico, before, during and after Massive Vaccination
Lenin Domínguez-Ramírez, Francisca Sosa-Jurado, Guadalupe Díaz-Sampayo, Itzel Solis-Tejeda, Francisco Rodríguez-Pérez, Rosana Pelayo, Gerardo Santos-López, Paulina Cortes-Hernandez
Vaccines.2023; 11(11): 1676. CrossRef - Study of optimal vaccination strategies for early COVID-19 pandemic using an age-structured mathematical model: A case study of the USA
Giulia Luebben, Gilberto González-Parra, Bishop Cervantes
Mathematical Biosciences and Engineering.2023; 20(6): 10828. CrossRef - HEMOGRAM INDICATORS IN PATIENTS WITH COMMUNITY-ACQUIRED PNEUMONIA CAUSED BY COVID-19 DEPENDING ON THE CHARLSON COMORBIDITY INDEX
T. M. Homeliuk, M. I. Marushchak
Bulletin of Problems Biology and Medicine.2023; 1(1): 161. CrossRef - Correlates of In-Hospital COVID-19 Deaths: A Competing Risks Survival Time Analysis of Retrospective Mortality Data
Ashish Goel, Alpana Raizada, Ananya Agrawal, Kamakshi Bansal, Saurabh Uniyal, Pratima Prasad, Anil Yadav, Asha Tyagi, RS Rautela
Disaster Medicine and Public Health Preparedness.2022; 16(5): 1889. CrossRef - Inference on the Beta Type I Generalized Half Logistic Distribution under Right-Censored Observation with Application to COVID-19
Phillip Oluwatobi Awodutire, Ethelbert Chinaka Nduka, Maxwell Azubike Ijomah, Oluwatosin Ruth Ilori, Oluwafemi Samson Balogun, Niansheng Tang
International Journal of Mathematics and Mathematical Sciences.2022; 2022: 1. CrossRef - Association between chronic kidney disease and mortality in patients with a confirmed COVID-19 diagnosis
Jacqueline Betsabe Puicón-Suárez, Sandra Zeña-Ñañez, Virgilio E. Failoc-Rojas
PeerJ.2022; 10: e13437. CrossRef - The effects of hypertension on the prognosis of coronavirus disease 2019: a systematic review and meta-analysis on the interactions with age and antihypertensive treatment
Alimamy Umaru Kabia, Ping Li, Zhichao Jin, Xiaojie Tan, Yilong Liu, Yuqi Feng, Keyao Yu, Ming Hu, Dongming Jiang, Guangwen Cao
Journal of Hypertension.2022; 40(12): 2323. CrossRef - Associations of symptom combinations with in-hospital mortality of coronavirus disease-2019 patients using South Korean National data
Suyoung Jo, Hee-kyoung Nam, Heewon Kang, Sung-il Cho, Russell Kabir
PLOS ONE.2022; 17(8): e0273654. CrossRef - Epidemiological Profile and Social Welfare Index as Factors Associated with COVID-19 Hospitalization and Severity in Mexico City: A Retrospective Analysis
Mario Antonio Téllez-González, Juan Antonio Pineda-Juárez, Juan Antonio Suárez-Cuenca, Mónica Escamilla-Tilch, Daniel Santillán-Cortez, Silvia García, Sofía Lizeth Alcaraz-Estrada, Juan Carlos Pérez-Razo, Carlos Alberto Delgado-Quintana, Joel Vargas-Herná
International Journal of Environmental Research and Public Health.2022; 19(22): 14803. CrossRef - Trends of COVID-19 Admissions in an Italian Hub during the Pandemic Peak: Large Retrospective Study Focused on Older Subjects
Andrea Ticinesi, Antonio Nouvenne, Nicoletta Cerundolo, Alberto Parise, Beatrice Prati, Angela Guerra, Tiziana Meschi
Journal of Clinical Medicine.2021; 10(5): 1115. CrossRef - Ethnic disparities in COVID-19 mortality in Mexico: A cross-sectional study based on national data
Ismael Ibarra-Nava, Kathia G. Flores-Rodriguez, Violeta Ruiz-Herrera, Hilda C. Ochoa-Bayona, Alfonso Salinas-Zertuche, Magaly Padilla-Orozco, Raul G. Salazar-Montalvo, Mary Hamer Hodges
PLOS ONE.2021; 16(3): e0239168. CrossRef - Association of Kidney Disease With Outcomes in COVID‐19: Results From the American Heart Association COVID‐19 Cardiovascular Disease Registry
Anjali Rao, Sagar Ranka, Colby Ayers, Nicholas Hendren, Anna Rosenblatt, Heather M. Alger, Christine Rutan, Wally Omar, Rohan Khera, Kamal Gupta, Purav Mody, Christopher DeFilippi, Sandeep R. Das, S. Susan Hedayati, James A. de Lemos
Journal of the American Heart Association.2021;[Epub] CrossRef - Risk Factors and Clinical Phenotypes Associated with Severity in Patients with COVID-19 in Northeast Mexico
Francisco Javier García-Alvarado, Melisa Alejandra Muñoz-Hernández, Elida Moran Guel, Marisela del Rocío González-Martínez, Maritza Argelia Macías Corral, Héctor Alberto Delgado-Aguirre
Vector-Borne and Zoonotic Diseases.2021; 21(9): 720. CrossRef - COVID‐19‐related deaths among women of reproductive age in Brazil: The burden of postpartum
Roxana Knobel, Maíra L. S. Takemoto, Marcos Nakamura‐Pereira, Mariane O. Menezes, Vicente K. Borges, Leila Katz, Melania M. R. Amorim, Carla B. Andreucci
International Journal of Gynecology & Obstetrics.2021; 155(1): 101. CrossRef - Autosomal Dominant Polycystic Kidney Disease Does Not Significantly Alter Major COVID-19 Outcomes among Veterans
Xiangqin Cui, Julia W. Gallini, Christine L. Jasien, Michal Mrug
Kidney360.2021; 2(6): 983. CrossRef - The Association of Asthma With COVID-19 Mortality: An Updated Meta-Analysis Based on Adjusted Effect Estimates
Hongjie Hou, Jie Xu, Yang Li, Yadong Wang, Haiyan Yang
The Journal of Allergy and Clinical Immunology: In Practice.2021; 9(11): 3944. CrossRef - Factors Associated With Severe COVID-19 Infection Among Persons of Different Ages Living in a Defined Midwestern US Population
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Mayo Clinic Proceedings.2021; 96(10): 2528. CrossRef - Diabetes, hypertension, body mass index, smoking and COVID-19-related mortality: a systematic review and meta-analysis of observational studies
Yahya Mahamat-Saleh, Thibault Fiolet, Mathieu Edouard Rebeaud, Matthieu Mulot, Anthony Guihur, Douae El Fatouhi, Nasser Laouali, Nathan Peiffer-Smadja, Dagfinn Aune, Gianluca Severi
BMJ Open.2021; 11(10): e052777. CrossRef - Stability, Bifurcation, and a Pair of Conserved Quantities in a Simple Epidemic System with Reinfection for the Spread of Diseases Caused by Coronaviruses
Jorge Fernando Camacho, Cruz Vargas-De-León, Hassan A. El Morshedy
Discrete Dynamics in Nature and Society.2021; 2021: 1. CrossRef - Evaluation of Treatment Outcome for Pneumonia among Pre-Vaccinated COVID-19 Patients with/without Comorbidity in a Public Hospital in Bengkulu, Indonesia
Diana Laila Ramatillah, Siew Hua Gan, Syed Azhar Syed Sulaiman, Dama Puja, Usman Abubakar, Ammar Ali Saleh Jaber, Stefanus Lukas, Nina Jusnita
Vaccines.2021; 9(12): 1411. CrossRef
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